Jocelyn Rivera
Schering-Plough
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Publication
Featured researches published by Jocelyn Rivera.
ACS Medicinal Chemistry Letters | 2010
Kamil Paruch; Michael P. Dwyer; Carmen Alvarez; Courtney Brown; Tin-Yau Chan; Ronald J. Doll; Kerry Keertikar; Chad E. Knutson; Brian Mckittrick; Jocelyn Rivera; Randall R. Rossman; Greg Tucker; Thierry O. Fischmann; Alan Hruza; Vincent Madison; Amin A. Nomeir; Yaolin Wang; Paul Kirschmeier; Emma Lees; David Parry; Nicole Sgambellone; Wolfgang Seghezzi; Lesley Schultz; Frances Shanahan; Derek Wiswell; Xiaoying Xu; Quiao Zhou; Ray Anthony James; Vidyadhar M. Paradkar; Haengsoon Park
Inhibition of cyclin-dependent kinases (CDKs) has emerged as an attractive strategy for the development of novel oncology therapeutics. Herein is described the utilization of an in vivo screening approach with integrated efficacy and tolerability parameters to identify candidate CDK inhibitors with a suitable balance of activity and tolerability. This approach has resulted in the identification of SCH 727965, a potent and selective CDK inhibitor that is currently undergoing clinical evaluation.
Tetrahedron Letters | 2002
Jocelyn Rivera; Nilukshi Jayasuriya; Dinanath F. Rane; Kerry Keertikar; J. Albert Ferreira; Jiangping Chao; Keith P. Minor; Timothy J. Guzi
The synthesis of several 1H-imidazol-1-ylmethylpiperidines is described. A method for the regioselective isolation of 1,4-disubstituted imidazoles utilizing the selective quaternization of the 1,5-disubstituted regioisomer was developed.
Archive | 2002
Timothy J. Guzi; Kamil Paruch; Alan K. Mallams; Jocelyn Rivera; Ronald J. Doll; Viyyoor M. Girijavallabhan; Jonathan A. Pachter; Yi-Tsung Liu; Anil K. Saksena
Bioorganic & Medicinal Chemistry Letters | 2007
Kamil Paruch; Michael P. Dwyer; Carmen Alvarez; Courtney Brown; Tin-Yau Chan; Ronald J. Doll; Kerry Keertikar; Chad E. Knutson; Brian Mckittrick; Jocelyn Rivera; Randall R. Rossman; Greg Tucker; Thierry O. Fischmann; Alan Hruza; Vincent Madison; Amin A. Nomeir; Yaolin Wang; Emma Lees; David Parry; Nicole Sgambellone; Wolfgang Seghezzi; Lesley Schultz; Fran Shanahan; Derek Wiswell; Xiaoying Xu; Quiao Zhou; Ray Anthony James; Vidyadhar M. Paradkar; Haengsoon Park; Laura R. Rokosz
Archive | 2005
Timothy J. Guzi; Kamil Paruch; Michael P. Dwyer; Ronald J. Doll; Viyyoor M. Girijavallabhan; Alan K. Mallams; Carmen Alvarez; Kartik M. Keertikar; Jocelyn Rivera; Tin-Yau Chan; Vincent Madison; Thierry O. Fischmann; Lawrence W. Dillard; Vinh D. Tran; Zhen Min He; Ray Anthony James; Haengsoon Park; Vidyadhar M. Paradkar; Douglas W. Hobbs
Archive | 2006
Timothy J. Guzi; Kamil Paruch; Michael P. Dwyer; Ronald J. Doll; Viyyoor M. Girijavallabhan; Alan K. Mallams; Carmen Alvarez; Kartik M. Keertikar; Jocelyn Rivera; Tin Yau Chan; Vincent Madison; Thierry O. Fischmann; Lawrence W. Dillard; Vinh D. Tran; Zhen Min He; Ray Anthony James; Haengsoon Park; Vidyadhar M. Paradkar; Douglas W. Hobbs
Archive | 2013
Timothy J. Guzi; Madison Vincent S; Tin-Yau Chan; Vincent S. Madison; Fischmann Thierry O; Dillard Lawrence W; Tran Vinh D; Min He Zhen; Anthony James Ray; Haengsoon Park; Paradkar Vidyadhar M; Kamil Paruch; Walsh Hobbs Douglas; Dwyer Michael P; Doll Ronald J; Moopil Girijavallabhan Viyyoor; Alan K. Mallams; Alvarez Carmen S; Keertikar Kartik M; Jocelyn Rivera
Archive | 2010
Timothy J. Guzi; Kamil Paruch; Michael P. Dwyer; Ronald J. Doll; Viyyoor M. Girijavallabhan; Alan K. Mallams; Carmen Alvarez; Kartik M. Keertikar; Jocelyn Rivera; Tin-Yau Chan; Vincent S. Madison; Thierry O. Fischmann; Lawrence W. Dillard; Vinh D. Tran; Zhen Min He; Ray Anthony James; Haengsoon Park; Vidyadhar M. Paradkar; Douglas W. Hobbs
Archive | 2010
Carmen Alvarez; Tin-Yau Chan; Lawrence W. Dillard; Ronald J. Doll; Michael P. Dwyer; Thierry O. Fischmann; Viyyoor M. Girijavallabhan; Timothy J. Guzi; Zhen Min He; Douglas W. Hobbs; Ray Anthony James; Kartik M. Keertikar; Vincent S. Madison; Alan K. Mallams; Vidyadhar M. Paradkar; Haengsoon Park; Kamil Paruch; Jocelyn Rivera; Vinh D. Tran; マラムス アラン; パルチ カミル; エム． キールティカール カルティック; エス． アルバレス カルメン; リベラ ジョセリン; ウォルシュ ホッブス ダグラス; ミン ホー チェン; ティン−ヤウ チャン; オー． フィッシュマン ティエリー; ジェイ． グジ ティモシー; エム． パラドカル ビドヤドハー
Archive | 2008
Timothy J. Guzi; Kamil Paruch; Michael P. Dwyer; Ronald J. Doll; Viyyoor M. Girijavallabhan; Alan K. Mallams; Carmen Alvarez; Kartik M. Keertikar; Jocelyn Rivera; Tin-Yau Chan; Vincent S. Madison; Thierry O. Fischmann; Paul Kirschmeier; Rajat Bannerji; Lawrence W. Dillard; Vinh D. Tran; Zhenmin He; Ray Anthony James; Haengsoon Park; Vidyadhar M. Paradkar; Douglas W. Hobbs
