Joel B. Fisher

Rapid identification of congenital heart disease by transmission of echocardiograms

citation patterns in hypertrophic cardiomyopathy. Am Heart J 1981; 101:233-4. 7. Bharati S, Strassbert B, Bilitch M, Salibi H, Mandel W, Rosen MK, Lev M. Anatomic substrate for preexcitation in idiopathic myocardial hypertrophy with fibroelastosis of the left ventricle. Am J Cardiol 1981;48:47-58. 8. MacRae C, Ghaisas N, McGarry K, McKenna W, Seidman JG, Seidman CE. Familial hypertrophic cardiomyopathy with Wolff-ParkinsonWhite syndrome maps to a locus on chromosome 7q3. Circulation 1994; 90:I-25.

USE OF A BETA-AGONIST IN VENTILATED, VERY-LOW-BIRTH-WEIGHT BABIES : A LONGITUDINAL EVALUATION

To determine if there is a specific postnatal (PNA) or postconceptional age (PCA) at which ventilated preterm infants respond to beta-agonists, we evaluated 15 infants with a mean gestational age of 26.5 +/- 1.5 weeks and mean birth weight of 0.89 +/- 0.23 kg who required mechanical ventilation at 10 days of age. Weekly pulmonary function testing (PFT) was performed before and 1 h after administration of albuterol. Taking the group as a whole, as well as individual babies, regression analysis showed no relationship between positive response and either PNA or PCA. Evaluation of individual infants, however, showed that some consistently responded to beta-agonists whereas others did not. We recommend individual PFT to identify those infants who will benefit from use of beta-agonists.