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Dive into the research topics where John E. Lawson is active.

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Featured researches published by John E. Lawson.


Bioorganic & Medicinal Chemistry Letters | 1993

Preparation and in vitro biological evaluation of the enantiomers of the diydropyridine BMY 20014, a combination calcium and α1-adrenoreceptor antagonist

John E. Lawson; Graham S. Poindexter; Donald A. Owens; Robert L. Cavanagh; Gregory D. Goggins; J. George Sarmiento; Bonnie Bleiberg; Edward O. Weselcouch

Abstract The R and S enantiomers of the 1,4-dihydropyridine amide BMY 20014 (1) were prepared from the corresponding chiral carboxylic acids via carbonyldiimidazole couplings. Pharmacologically, the R-(−)-amide 5a demonstrates more potent Ca++ channel and α1-adrenoreceptor antagonist properties than the S-(+) isomer. The R-(−) and S-(+) enantiomers of the dihydropyridine amide BMY 20014 (1) were prepared from the corresponding chiral carboxylic acids via carbonyldiimidazole couplins. Pharmacologically, the R-(−)-amide 5a demonstrates more potent Ca++ and α1-adrenoreceptor antagonist properties than the S-(+)- isomer.


Archive | 1993

Nucleic acids encoding microsomal trigyceride transfer protein

R. Wetterau Ii John; Daru Young Sharp; Richard E. Gregg; Scott A. Biller; John K. Dickson; R. Michael Lawrence; John E. Lawson; Henry M. Holava; Richard Anthony Partyka


Archive | 1998

Mikrosoomse triglütseriidi transportproteiini inhibiitorid ja meetod

Daru Young Sharp; Richard E. Gregg; Scott A. Biller; John A. Dickson; R. Michael Lawrence; David R. Magnin; Michael A. Poss; Jeffrey A. Robl; Richard B. Sulsky; Joseph A. Tino; John E. Lawson; Henry M. Holava; Richard Anthony Partyka; John R. Wetterau


Archive | 1997

Microsomal triglyceride transfer protein inhibitor, and method

Ii John R. Wetterau; Daru Young Sharp; Richard E. Gregg; Scott A. Biller; John A. Dickson; R. Michael Lawrence; David R. Magnin; Michael A. Poss; Jeffrey A. Robl; Richard B. Sulsky; Joseph A. Tino; John E. Lawson; Henry M. Holava; Richard Anthony Partyka


Archive | 1996

Inhibidores de la proteina microsomal de transferencia de trigliceridos y procedimiento.

Scott A. Biller; John A. Dickson; Richard E. Gregg; Henry M. Holava; R. Michael Lawrence; John E. Lawson; David R. Magnin; Richard Anthony Partyka; Michael A. Poss; Jeffrey A. Robl; Daru Young Sharp; Richard B. Sulsky; Joseph A. Tino; John R. Wetterau


Archive | 1996

Inhibitoren von mikrosomalem triglycerid-transfer-protein und verfahren

Scott A. Biller; John A. Dickson; Richard E. Gregg; Henry M. Holava; R. Michael Lawrence; John E. Lawson; David R. Magnin; Richard Anthony Partyka; Michael A. Poss; Jeffrey A. Robl; Daru Young Sharp; Richard B. Sulsky; Joseph A. Tino; John R. Wetterau


Archive | 1996

Inhibiteurs de la proteine microsomiale de transfert des triglycerides et procede d'utilisation

Scott A. Biller; John A. Dickson; Richard E. Gregg; Henry M. Holava; R. Michael Lawrence; John E. Lawson; David R. Magnin; Richard Anthony Partyka; Michael A. Poss; Jeffrey A. Robl; Daru Young Sharp; Richard B. Sulsky; Joseph A. Tino; John R. Wetterau


Archive | 1996

Inhibitors of microsomal triglyceride transfer protein and procedure.

Scott A. Biller; John A. Dickson; Richard E. Gregg; Henry M. Holava; R. Michael Lawrence; John E. Lawson; David R. Magnin; Richard Anthony Partyka; Michael A. Poss; Jeffrey A. Robl; Daru Young Sharp; Richard B. Sulsky; Joseph A. Tino; John R. Wetterau


Archive | 1994

Inhibitoren des microsomalen Triglyceridtransferproteins

Ii John R. Wetterau; Daru Young Sharp; Richard E. Gregg; Scott A. Biller; John K. Dickson; Michael R Lawrence; John E. Lawson; Henry M. Holava; Richard Anthony Partyka


Archive | 1994

Microsomal trigyceride transfer protein inhibitor

Scott A. Biller; John K. Dickson; Richard E. Gregg; Henry M. Holava; R. Michael Lawrence; John E. Lawson; Richard Anthony Partyka; Daru Young Sharp; Ii John R. Wetterau; アール・マイケル・ローレンス; ジョン・アール・ウェッテロー・ザ・セカンド; ジョン・イー・ローソン; ジョン・ケイ・ディクソン; スコット・エイ・ビラー; ダル・ヤング・シャープ; ヘンリー・エム・ホラバ; リチャード・イー・グレッグ; リチャード・エイ・パーティカ

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