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Featured researches published by John Edward Richardson.


Green Chemistry | 2001

Green chemistry measures for process research and development

David J. C. Constable; Alan D. Curzons; Luisa M. Freitas dos Santos; Graham Richard Geen; Robert E. Hannah; John D. Hayler; John Kitteringham; Michael A. McGuire; John Edward Richardson; Paul W. Smith; R. Lee Webb; Marvin Sungwhan Yu

A set of metrics has been developed which enables a simple assessment to be made of batch processes in terms of waste, energy usage, and chemistry efficiency. It is intended to raise awareness of green chemistry by providing a tool to assist chemists in monitoring progress in the reduction of environmental impact as they design new routes and modify processes.


Archive | 1986

Anti-depressant crystalline paroxetine hydrochloride hemihydrate

Roger Duncan Barnes; Marian Wladylaw Wood-Kaczmar; Alan D. Curzons; Ian Robert Lynch; John Edward Richardson; Philip Christopher Buxton


Archive | 1986

Piperidine derivatives, their preparation, and their use as medicaments

Roger Duncan Barnes; Marian Wladylaw Wood-Kaczmar; John Edward Richardson; Ian Robert Lynch; Philip Christopher Buxton; Alan D. Curzons


Organic Process Research & Development | 1999

Multikilogram-Scale Synthesis of a Biphenyl Carboxylic Acid Derivative Using a Pd/C-Mediated Suzuki Coupling Approach

David S. Ennis; Julie McManus; ‡ Wladyslaw Wood-Kaczmar; John Edward Richardson; and Gillian E. Smith; Alexis Carstairs


Archive | 1986

Piperidine derivative, its preparation, and its use as medicament

Roger Duncan C; O Beecham Pharmaceuticals Barnes; Marian Wladylaw Wood-Kaczmar; John Edward Richardson; Ian Robert C; O Beecham Pharmaceuticals Lynch; Philip Christopher C; O Beecham Pharmaceut Buxton; Alan D. Curzons


Organic Process Research & Development | 2000

Development of a Catalytic Tributyltin Hydride Cyclisation Process

Robin P. Attrill; Mark A. Blower; Keith R. Mulholland; John K. Roberts; John Edward Richardson; and Martin J. Teasdale; Andre Wanders


Organic Process Research & Development | 2018

Development and Scale-Up of a Manufacturing Route for the Non-nucleoside Reverse Transcriptase Inhibitor GSK2248761A (IDX-899): Synthesis of an Advanced Key Chiral Intermediate

Richard K. Bellingham; Gary T. Borrett; Guillaume Bret; Bernadette Choudary; David Colclough; Jerome F. Hayes; John D. Hayler; Neil Hodnett; Alan Ironmonger; Augustine Ochen; David Pascoe; John Edward Richardson; Erica Vit; François-René Alexandre; Catherine Caillet; Agnès Amador; Stéphanie Bot; Séverine Bonaric; Daniel Da Costa; Marie-Pierre Lioure; Arlène Roland; Elodie Rosinovsky; Christophe Claude Parsy; Cyril B. Dousson


Archive | 1986

Crystalline paroxetine hcl

Roger Duncan Barnes; Marian Wladylaw Wood-Kaczmar; Alan D. Curzons; Ian Robert Lynch; John Edward Richardson; Philip Christopher Buxton


Archive | 1991

Process for the preparation of 4-Phenylpiperidine derivatives

Roger Duncan Barnes; Marian Wladylaw Wood-Kaczmar; Alan D. Curzons; Ian Robert Lynch; John Edward Richardson; Philip Christopher Buxton


Archive | 1986

Piperidinderivat, seine herstellung und seine verwendung als arzneimittel. The piperidine derivative, its preparation and its use as a medicament.

Roger Duncan Barnes; Marian Wladylaw Wood-Kaczmar; John Edward Richardson; Ian Robert Lynch; Philip Christopher Buxton; Alan D. Curzons

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