John J. Curtin

Development and validation of a brief form of the Multidimensional Personality Questionnaire.

The Multidimensional Personality Questionnaire (MPQ; A. Tellegen, 1982, in press) provides for a comprehensive analysis of personality at both the lower order trait and broader structural levels. Its higher order dimensions of Positive Emotionality, Negative Emotionality, and Constraint embody affect and temperament constructs, which have been conceptualized in psychobiological terms. The MPQ thus holds considerable potential as a structural framework for investigating personality across varying levels of analysis, and this potential would be enhanced by the availability of an abbreviated version. This article describes efforts to develop and validate a brief (155-item) form, the MPQ-BF. Success was evidenced by uniformly high correlations between the brief- and full-form trait scales and consistency of higher order structures. The MPQ-BF is recommended as a tool for investigating the genetic, neurobiological, and psychological substrates of personality.

Assessment of Psychopathy in a Population of Incarcerated Adolescent Offenders

The reliability, validity, and factor structure of a modified version of the Psychopathy ChecklistRevised (PCL-R) for adolescents was investigated, completed using file information only, in a sample of incarcerated Black and White male adolescents. Interrater reliability and internal consistency were high, and confirmatory factor analyses and coefficients of congruence showed that the factor structure in this sample resembled the 2-factor solution found in adults. No significant racial differences were found for reliability or mean PCL-R scores. In addition, relationships between PCL-R scores and psychometric measures and behavioral indicators of maladjustment were similar to those previously found in adult populations. The construct of psychopathy, as defined by the PCLR modified for use with adolescents, appears applicable to both Black and White adolescent male offenders. The study gives evidence for the structural and substantive validity of the modified PCLR in this population. The Psychopathy Checklist--Revised (PCL-R; Hare, 1991 ) has proven reliable and useful in subgrouping adult offenders who are incarcerated, White, and male. This study examined the usefulness of this instrument with a population of incarcerated Black and White male adolescent offenders.

Neural Signals for the Detection of Unintentional Race Bias

We examined the hypothesis that unintentional race-biased responses may occur despite the activation of neural systems that detect the need for control. Participants completed a sequential priming task that induced race-biased responses on certain trials while electroencephalography was recorded. The error-related negativity (ERN) wave, a component of the event-related potential with an anterior cingulate generator, was assessed to index neural signals detecting the need for control. Responses attributed to race bias produced larger ERNs than responses not attributed to race bias. Although race-biased responses were prevalent across participants, those with larger ERNs to race-biased responses showed higher levels of control throughout the task (e.g., greater accuracy and slowed responding following errors). The results indicate that race-biased responses may be made despite the activation of neural systems designed to detect bias and to recruit controlled processing.

Alcohol and cognitive control: Implications for regulation of behavior during response conflict.

Alcohol intoxication often leads to dysregulated behavior in contexts characterized by conflict between prepotent response tendencies and incompatible alternative responses. Recent research has identified 2 components of an anterior executive attention system that are essential for adaptive behavior when response conflict exists. Event-related potential (ERP) measures of evaluative and regulative cognitive control were collected to determine if impaired executive attention was responsible for observed behavior deficits when intoxicated. Intoxicated participants displayed task performance deficits on incongruent color-naming trials relative to sober controls. Alcohol did not affect P3 magnitude/latency, indicating that timing and integrity of stimulus evaluation remained intact. In contrast, alcohol did reduce frontal components of ERP that index evaluative and regulative cognitive control processes.

Psychopathy and Physiological Response to Emotionally Evocative Sounds.

Despite considerable evidence that psychopathic criminals are deviant in their emotional reactions, few studies have examined responses to both pleasurable and aversive stimuli or assessed the role of different facets of psychopathy in affective deviations. This study investigated physiological reactions to emotional sounds in prisoners selected according to scores on the 2 factors of Hares Psychopathy Checklist--Revised (PCL-R; R. D. Hare, 1991). Offenders high on the PCL-R emotional-interpersonal factor, regardless of scores on the social deviance factor, showed diminished skin conductance responses to both pleasant and unpleasant sounds, suggesting a deficit in the action mobilization component of emotional response. Offenders who scored high only on the social deviance factor showed a delay in heart rate differentiation between affective and neutral sounds. These findings indicate abnormal reactivity to both positive and negative emotional stimuli in psychopathic individuals, and suggest differing roles for the 2 facets of psychopathy in affective processing deviations.

Risk Factors in the Relationship Between Gender and Crack/Cocaine

Female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than on any other drug. Additionally, female inner-city substance users evidence greater crack/cocaine use and are more likely to be dependent on this drug than their male counterparts, despite no consistent difference demonstrated in use and dependence across other drugs. Because no published work has empirically examined the factors underlying this link between females and crack/cocaine, the current study examined the role of theoretically relevant personality and environmental variables. Among 152 (37% female) individuals in a residential substance-use treatment program, females evidenced greater use of crack/cocaine (current and lifetime heaviest) and were significantly more likely to evidence crack/cocaine dependence than their male counterparts. In contrast, no gender differences were found for any other substance across alcohol, cannabis, and hallucinogens (including PCP). Surprisingly, females were more impulsive than their male counterparts, with impulsivity serving as a risk factor in the relationship between gender and crack/cocaine dependence and lifetime heaviest use. Females also evidenced higher levels of negative emotionality and childhood abuse, but neither variable served as a risk factor in the relationship between gender and crack/cocaine dependence or use. Limitations and future directions are discussed, including the need for further exploration of impulsivity across its various dimensions as well as the inclusion of additional variables such as social context variables to account more fully for this complex link between gender and crack/cocaine.

Alcohol Affects Emotion Through Cognition

Determining how cognition and emotion interact is pivotal to an understanding of human behavior and its disorders. Available data suggest that changes in emotional reactivity and behavior associated with drinking are intertwined with alcohols effects on cognitive processing. In the study reported here, we demonstrated that alcohol dampens anticipatory fear and response inhibition in human participants not by directly suppressing subcortical emotion centers, as posited by traditional tension-reduction theories, but instead by impairing cognitive-processing capacity. During intoxication, reductions in fear response (assessed via startle potentiation) occurred only under dual-stimulus conditions, and coincided with reduced attentional processing of threat cues as evidenced by brain response (assessed via P3 event-related potentials). The results are consistent with higher cortical mediation of alcohols effects on fear, and illustrate more broadly how disruption of a cognitive process can lead to alterations in emotional reactivity and adaptive behavior.

Age and physical activity influences on action monitoring during task switching

Behavioral and neuroelectric indices of action monitoring were compared for 53 high and low physically active older (60-71 years) and younger (18-21 years) adults during a task-switching paradigm in which they performed a task repeatedly or switched between two different tasks. The error-related negativity (ERN) of a response-locked event-related brain potential (ERP) and behavioral measures of response speed and accuracy were measured during the heterogeneous condition (switching randomly between two tasks) of the switch task. Results indicated that older adults exhibited a greater relative slowing in RT during heterogeneous blocks and smaller ERN amplitude compared to younger adults. Additionally, physical activity differences revealed a relatively smaller global switch cost for physically active older adults and decreased ERN amplitude, as well as increased post-error response slowing for older and younger physically active participants, compared to their less physically active counterparts. The findings suggest that both age and physical activity participation influence behavioral and neuroelectric indices of action monitoring and provide further evidence for the beneficial effects of physical activity on executive control.

Health beliefs, health locus of control, and women's mammography behavior.

Research has shown that routine mammography screening can significantly reduce mortality from breast cancer. The use of mammography screening, however, remains well below national goals. In an effort to understand the factors that influence womens mammography behaviors, this study explored the relation between health beliefs, locus of control, and womens mammography practice. Survey instruments used were Champions health belief scales and the Multidimensional Health Locus of Control (MHLC) scales. The study used a convenience sample of 25 African Americans and 72 white women ages 35 to 84. Findings showed that women who participated in mammography screening were significantly more likely to perceive greater benefits, greater health motivation, and fewer barriers to screening than those who did not participate. These same three variables were similarly associated with greater frequency of receiving mammograms. It also was found that perceived benefits and health motivation were significantly correlated with shorter duration of time since the last mammogram. No support was found for perceived susceptibility, perceived seriousness, and health locus of control as predictors of womens mammography behavior. Implications for nursing research in further examining the MHLC and the Health Belief Model construct of susceptibility as they relate to mammography behavior are identified. Practice implications for nurses are suggested.

Specifying the Attentional Selection That Moderates the Fearlessness of Psychopathic Offenders

Our previous research demonstrated that psychopathy-related fear deficits involve abnormalities in attention that undermine sensitivity to peripheral information. In the present study, we specified this attention-mediated abnormality in a new sample of 87 prisoners assessed with Hare’s Psychopathy Checklist-Revised (Hare, 2003). We measured fear-potentiated startle (FPS) under four conditions that crossed attentional focus (threat vs. alternative) with early versus late presentation of threat cues. The psychopathic deficit in FPS was apparent only in the early-alternative-focus condition, in which threat cues were presented after the alternative goal-directed focus was established. Furthermore, psychopathy interacted with working memory capacity in the late-alternative-focus condition, which suggests that individuals high in psychopathy and working memory capacity were able to maintain a set-related alternative focus that reduced FPS. The results not only provide new evidence that attention moderates the fearlessness of psychopathic individuals, but also implicate an early attention bottleneck as a proximal mechanism for deficient response modulation in psychopathy.