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John W. Semple

Canadian Blood Services

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Publication

Featured researches published by John W. Semple.

Blood | 1995

Indirect allorecognition of platelets by T helper cells during platelet transfusions correlates with anti-major histocompatibility complex antibody and cytotoxic T lymphocyte formation.

John W. Semple; Edwin R. Speck; Youli Milev; Victor S. Blanchette; Jane E. Freedman

Blood | 2007

Epitope specificity and isotype of monoclonal anti-D antibodies dictate their ability to inhibit phagocytosis of opsonized platelets

Mimi Kjaersgaard; Rukhsana Aslam; Michael Kim; Edwin R. Speck; John Freedman; Donald I.H. Stewart; Erik J. Wiersma; John W. Semple

Blood | 1993

Downregulation of the anti-HLA alloimmune response by variable region-reactive (anti-idiotypic) antibodies in leukemic patients transfused with platelet concentrates.

E Atlas; John Freedman; Victor S. Blanchette; Kazatchkine; John W. Semple

Blood | 1996

Recipient humoral immunity against leukoreduced allogeneic platelets is suppressed by aminoguanidine, a selective inhibitor of inducible nitric oxide synthase

A Bang; Edwin R. Speck; Victor S. Blanchette; Jane E. Freedman; John W. Semple

Drug Discovery Today: Disease Mechanisms | 2006

Mechanisms underlying autoimmunity in hematology

John W. Semple; John Freedman

Archive | 2016

Naturally processed heterodimeric disulfide-linked insulin peptides bind to major histocompatibility class II molecules on thymic

Frederique Forquet; John W. Semple; Edwin R. Speck; Terry L. Delovitch

Archive | 2013

sensitive to therapy mediated responses that are differentially - T cell + antibody- and CD8 A murine model of severe immune thrombocytopenia is induced by

John W. Semple; Pingguo Chen; Kim Sahib; Heyu Ni; Alan H. Lazarus; M. Bernadette Garvey; Rukhsana Aslam; Edwin R. Speck; Michael Kim; Norman Cridland; Michelle Lee

Archive | 2013

phagocytosis of IgG opsonized platelets Platelet-bound lipopolysaccharide enhances Fc receptor-mediated

John W. Semple; Rukhsana Aslam; Michael Kim; Edwin R. Speck; John Freedman

Archive | 2012

model of immune thrombocytopenia with their peripheral deficiency and thrombocytopenia in a murine T regulatory cells is associated + FoxP3 + CD25 +

Heyu Ni; John Freedman; John W. Semple; Rukhsana Aslam; Yu Hu; Simon Gebremeskel; George B. Segel; Edwin R. Speck; Li Guo

Archive | 2010

therapeutic effects of IVIg? A role for IL-1 receptor antagonist or other cytokines in the acute

Andrew R. Crow; Seng Song; John W. Semple; John Freedman; Alan H. Lazarus

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Collaboration

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John Freedman

University of Toronto

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Edwin R. Speck

St. Michael's Hospital

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Rukhsana Aslam

St. Michael's Hospital

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Victor S. Blanchette

St. Michael's Hospital

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Alan H. Lazarus

St. Michael's Hospital

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Michael Kim

St. Michael's Hospital

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Heyu Ni

Canadian Blood Services

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Pingguo Chen

St. Michael's Hospital

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Jane E. Freedman

University of Massachusetts Medical School

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Adriana Hornstein

St. Michael's Hospital

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