Joly Seth

Systemic side-effects of topical corticosteroids

With the introduction of topical corticosteroids, a milestone has been achieved in dermatologic therapy; owing to its potent anti-inflammatory and ant proliferative effects, it became possible to treat some hitherto resistant dermatoses. But this magic drug can cause enough mischief if used inappropriately. Children are more susceptible to the systemic adverse effects because of enhanced percutaneous absorption through their tender skin. So, systemic side effects should be kept in mind while prescribing this therapeutically valuable topical medicament.

Dermatitis neglecta -- A dirty dermatosis: Report of three cases

Dermatitis neglecta is a condition that results from inadequate frictional cleansing leading to accumulation of corneocytes, sebum and sweat ultimately resulting in hyper-pigmented patch or verrucous plaque. Recognizing this condition avoids unnecessary, aggressive diagnostic and therapeutic procedures. Here we report three cases of dermatitis neglecta in whom the dermatitis developed as a result of intentional neglect of personal hygiene.

Nodulo-ulcerative Tuberculosis of the Glans Penis-A Case Report and a Discussion on Nomenclature of Genital Tuberculosis.

Lupus vulgaris is a chronic paucibacillary form of cutaneous tuberculosis occurring in a person with a moderate to high degree of immunity. It commonly occurs over the buttocks and trunk in India. Involvement of the genitalia is uncommon, and lesions involving the penis, extremely rare with few cases reported worldwide. There also exists a confusion regarding nosology of tuberculosis of the genitalia. A brief discussion and review of literature are being discussed along with the report of a case of genital tuberculosis involving the glans penis.

Subcutaneous zygomycosis: A report of one case responding excellently to potassium iodide

Subcutaneous Zygomycosis is a rare opportunistic fungal infection caused by Basidiobolus ranarum. Though this entity is endemic in South India, limited numbers of cases have been reported from this part of the country. We report a case of subcutaneous zygomycosis in a 25 year old lady who presented with a nontender, firm to hard swelling over the upper-left arm. Finger was easily inserted below the indurated edge. Histopathology revealed suppurative granuloma with aseptate hyphae. Patient responded excellently to saturated solution of potassium iodide in subsequent visits.

Penile rhinosporidiosis: An unusual presentation and review of literature

Sir, Rhinosporidiosis is a chronic granulomatous infection caused by Rhinosporidium seeberi, a protistan parasite in the class Mesomycetozoea as per its recent taxonomic destination.1 Nose and eyes being the most common sites, penis and urethra manage to secure much lower rank among the sites of occurrence. Being a disease of world‐wide distribution, this menace has managed to intrude into several states of India quite effectively with Tamil Nadu and Kerala being at the top of the list. An increasing number of reports from different parts of West Bengal should sensitize us to know more about the modes of transmission and changing trends of the ecosystem in our state, if any.

Disseminated discoid lupus erythematosus with a linear lesion on the forearm and hand: A rare presentation and review of literature

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Graham–Little–Piccardi syndrome: A lens through beyond what is known

Graham–Little–Piccardi syndrome (GLPS) is a rare form of follicular lichen planus and comprises cicatricial alopecia of the scalp, noncicatricial alopecia of the axillae, and/or pubis and spinous follicular papules involving the trunk and extremities. We herein report a classic case of GLPS in a 49-year-old female. Uniqueness of our case is due to its additional features of frontal fibrosing alopecia (FFA). Although overlap between GLPS and FFA has been mentioned in literature, such numbers are scanty. Therapeutic response with oral steroid and retinoid is also far better in contrast to what is described in the existing literature.

Annular erythema in pediatric population

The term Annular Erythema encompases a great number of entity which commonly present as annular lesions. Differention of one from another is sometimes difficult. Consideration of different aspects such as age, sex, onset, duration etc of these so called less discussed entities as well as clinic-pathological correlation is required to solve the puzzle. We brought about a concise yet lucid review of annular erythema compraising salient features of each entity. We also went through extensive literature search to highlight latest updates and scientific information of the same.

Hypomelanosis of Ito with brain abscess: An incidental association or consequence of underlying structural defect?

Routine blood investigations explored low haemoglobin (8.7 g%), markedly raised total leukocyte count (25,300) with 70% neutrophil and positive C‐reactive protein (0.8 μg/L). Tests for malarial parasites, Widal test, liver function test, renal function test, and electrolyte assessment did not reveal any abnormality. Her chest X‐ray, echocardiography, and ultrasound found reports were normal. Computer tomography (CT) scan of the brain showed dilated ventricular system, debris and enhancement of ependyma suggestive of ventriculitis [Figure 3]. Most important finding was multiple hypo dense lesions with enhancing margins and intense peripheral edema over right temporal and occipital lobes suggestive of brain abscess [Figure 4]. We planned brain magnetic resonance imaging (MRI) to delineate structural anomaly if any. But grave general condition of the patient and financial restraint of the parents forced us to postpone MRI. Parents did not allow us for skin biopsy.

Menke's kinky hair disease with visual pathway defect: An association or coincidence?

Menke′s kinky hair disease (MKHD) is a rare X-linked recessive lethal disease of multisystem involvement. The predominant clinical findings are twisted, kinky, short, sparse, coarse, whitish, silver, or gray hair, eyebrows, and eyelashes. It is a disorder of defective copper metabolism leading to progressive neurodegeneration. The prognosis is poor with most of the patients dying at the age of 3-4 years due to respiratory failure secondary to infections. It generally always affects males with no racial predilection. We hereby report a classic case of Menke′s disease with visual pathway defect but normal brain imaging. To the best of our knowledge, this type of presentation has not been reported before in the literature. Awareness amongst physicians about this rare entity is important to prevent misdiagnosis and institution of necessary supportive care. Our observation further reinforces the importance of systemic evaluation in a suspected case of MKHD.