Joris Vangeneugden

Stimulus Similarity-Contingent Neural Adaptation Can Be Time and Cortical Area Dependent

Repetition of a stimulus results in decreased responses in many cortical areas. This so-called adaptation or repetition suppression has been used in several human functional magnetic resonance imaging studies to deduce the stimulus selectivity of neuronal populations. We tested in macaque monkeys whether the degree of neural adaptation depends on the similarity between the adapter and test stimulus. To manipulate similarity, we varied stimulus size. We recorded the responses of single neurons to different-sized shapes in inferior temporal (IT) and prefrontal cortical (PFC) areas while the animals were engaged in a size or shape discrimination task. The degree of response adaptation in IT decreased with increasing size differences between the adapter and the test stimuli in both tasks, but the dependence of adaptation on the degree of similarity between the adapter and test stimuli was limited mainly to the early phase of the neural response in IT. PFC neurons showed only weak size-contingent repetition effects, despite strong size selectivity observed with the same stimuli. Thus, based on the repetition effects in PFC, one would have erroneously concluded that PFC shows weak or no size selectivity in such tasks. These findings are relevant for the interpretation of functional magnetic resonance adaptation data: they support the conjecture that the degree of adaptation scales with the similarity between adapter and test stimuli. However, they also show that the temporal evolution of adaptation during the course of the response, and differences in the way individual regions react to stimulus repetition, may complicate the inference of neuronal tuning from functional magnetic resonance adaptation.

Distinct Mechanisms for Coding of Visual Actions in Macaque Temporal Cortex

Temporal cortical neurons are known to respond to visual dynamic-action displays. Many human psychophysical and functional imaging studies examining biological motion perception have used treadmill walking, in contrast to previous macaque single-cell studies. We assessed the coding of locomotion in rhesus monkey (Macaca mulatta) temporal cortex using movies of stationary walkers, varying both form and motion (i.e., different facing directions) or varying only the frame sequence (i.e., forward vs backward walking). The majority of superior temporal sulcus and inferior temporal neurons were selective for facing direction, whereas a minority distinguished forward from backward walking. Support vector machines using the temporal cortical population responses as input classified facing direction well, but forward and backward walking less so. Classification performance for the latter improved markedly when the within-action response modulation was considered, reflecting differences in momentary body poses within the locomotion sequences. Responses to static pose presentations predicted the responses during the course of the action. Analyses of the responses to walking sequences wherein the start frame was varied across trials showed that some neurons also carried a snapshot sequence signal. Such sequence information was present in neurons that responded to static snapshot presentations and in neurons that required motion. Our data suggest that actions are analyzed by temporal cortical neurons using distinct mechanisms. Most neurons predominantly signal momentary pose. In addition, temporal cortical neurons, including those responding to static pose, are sensitive to pose sequence, which can contribute to the signaling of learned action sequences.

Discrimination of locomotion direction in impoverished displays of walkers by macaque monkeys

A vast literature exists on human biological motion perception in impoverished displays, e.g., point-light walkers. Less is known about the perception of impoverished biological motion displays in macaques. We trained 3 macaques in the discrimination of facing direction (left versus right) and forward versus backward walking using motion-capture-based locomotion displays (treadmill walking) in which the body features were represented by cylinder-like primitives. The displays did not contain translatory motion. Discriminating forward versus backward locomotion requires motion information while the facing-direction/view task can be solved using motion and/or form. All monkeys required lengthy training to learn the forward-backward task, while the view task was learned more quickly. Once acquired, the discriminations were specific to walking and stimulus format but generalized across actors. Although the view task could be solved using form cues, there was a small impact of motion. Performance in the forward-backward task was highly susceptible to degradations of spatiotemporal stimulus coherence and motion information. These results indicate that rhesus monkeys require extensive training in order to use the intrinsic motion cues related to forward versus backward locomotion and imply that extrapolation of observations concerning human perception of impoverished biological motion displays onto monkey perception needs to be made cautiously.

Similarity, typicality, and category-level matching of morphed outlines of everyday objects.

During visual object categorisation, a match must be found between the input image and stored information about basic-level categories. Graf [2002 Form, Space and Object (Berlin: Wissenschaftlicher Verlag Berlin)] suggested the involvement of analogue transformational, shape-changing processes in aligning the memory representation of the category with the perceptual representation of the current stimulus. Here we compare the predictions of alignment models with those of exemplar-based models, using morphing between four exemplar outlines within each of eleven categories. Overall, with increasing transformational distance between two exemplars of the same category, reaction times to decide whether they belong to the same category in a sequential matching paradigm increased, while rated similarity between the two exemplars decreased. However, in contrast to alignment accounts, exemplar-based accounts can correctly predict the observed dissociation between typicality and categorisation time, and allow the observed deviations from sequential additivity and nonlinear relations between transformational distance and rated similarity. Discussion of integrations of exemplar-based theories with neglected processes, such as information accumulation, response competition, response priming, and gain-modulation leads to a view of the recognition process from input to response, which increases the validity and scope of modern exemplar-based categorisation and recognition models.

Discrimination of locomotion direction at different speeds: A comparison between macaque monkeys and algorithms

Models for visual motion perception exist since some time in neurophysiology as well as computer vision. In this paper, we present a comparison between a behavioral study performed with macaque monkeys and the output of a computational model. The tasks include the discrimination between left and right walking directions and forward vs. backward walking. The goal is to measure generalization performance over different walking and running speeds. We show in which cases the results match, and discuss and interpret differences.