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Publication
Featured researches published by Jose Aquino.
Bioorganic & Medicinal Chemistry Letters | 2010
Gary D. Probst; Simeon Bowers; Jennifer Sealy; Brian P. Stupi; Darren B. Dressen; Barbara Jagodzinska; Jose Aquino; Andrea Gailunas; Anh P. Truong; Luke Tso; Ying-Zi Xu; Roy K. Hom; Varghese John; Jay S. Tung; Michael A. Pleiss; John A. Tucker; Andrei W. Konradi; Hing L. Sham; Jacek Jagodzinski; Gergely Toth; Eric Brecht; Nanhua Yao; Hu Pan; May Lin; Dean R. Artis; Lany Ruslim; Michael P. Bova; Sukanto Sinha; Ted Yednock; Shawn Gauby
The structure-activity relationship of the prime region of hydroxyethylamine BACE inhibitors is described. Variation in the aryl linker region with 5- and 6-membered heterocycles provided compounds such as 33 with improved permeability and reduced P-gp liability compared to benzyl amine analog 1.
Archive | 2004
Jose Aquino; Varghese John; John A. Tucker; Shon R. Pulley; Ruth E. Tenbrink
Bioorganic & Medicinal Chemistry Letters | 2009
Jennifer Sealy; Anh P. Truong; L Tso; Gary D. Probst; Jose Aquino; Roy K. Hom; Barbara Jagodzinska; Darren B. Dressen; David W. G. Wone; Louis Brogley; John; Jay S. Tung; Michael A. Pleiss; John A. Tucker; Andrei W. Konradi; Michael S. Dappen; Gergley Tóth; Hu Pan; Lany Ruslim; J Miller; Michael P. Bova; Sukanto Sinha; Kevin P. Quinn; John-Michael Sauer
Bioorganic & Medicinal Chemistry Letters | 2010
Anh P. Truong; Gary D. Probst; Jose Aquino; Larry Fang; Louis Brogley; Jennifer Sealy; Roy K. Hom; John A. Tucker; Varghese John; Jay S. Tung; Michael A. Pleiss; Andrei W. Konradi; Hing L. Sham; Michael S. Dappen; Gergley Tóth; Nanhua Yao; Eric Brecht; Hu Pan; Dean R. Artis; Lany Ruslim; Michael P. Bova; Sukanto Sinha; Ted Yednock; Wes Zmolek; Kevin P. Quinn; John-Michael Sauer
Archive | 2005
Varghese John; Michel Maillard; Lawrence Fang; John A. Tucker; Louis Brogley; Jose Aquino; Simeon Bowers; Gary D. Probst; Jay S. Tung
Archive | 2004
Jose Aquino; Varghese John; John A. Tucker; Shon R. Pulley; Ruth E. Tenbrink
Archive | 2005
Varghese John; Michel Maillard; John A. Tucker; Jose Aquino; Barbara Jagodzinska; Louis Brogley; Jay S. Tung; Simeon Bowers; Darren B. Dressen; Gary D. Probst; Neerav Shah
Archive | 2005
Varghese John; Jennifer Sealy; Jose Aquino; Gary D. Probst; Jay Tung; Larry Fang; Barbara Jagodzinska
Archive | 2005
Varghese John; Michel Maillard; John A. Tucker; Jose Aquino; Jay Tung; Darren B. Dressen; Neerav Shah; R. Neitz
Archive | 2005
Varghese John; Michel Maillard; Barbara Jagodzinska; Jose Aquino; Gary D. Probst; Jay S. Tung