José Cegoñino

A Comparative Analysis of Different Treatments for Distal Femur Fractures using the Finite Element Method

The main objective of this work is the evaluation, by means of the finite element method (FEM) of the mechanical stability and long-term microstructural modifications in bone induced to three different kinds of fractures of the distal femur by three types of implants: the Condyle Plate, the less invasive stabilization system plate (LISS) and the distal femur nail (DFN). The displacement and the stress distributions both in bone and implants and the internal bone remodelling process after fracture and fixation are obtained and analysed by computational simulation. The main conclusions of this work are that distal femoral fractures can be treated correctly with the Condyle Plate, the LISS plate and the DFN. The stresses both in LISS and DFN implant are high especially around the screws. When respect to remodelling, the LISS produces an important resorption in the fractured region, while the other two implants do not strongly modify bone tissue microstructure.

Study of bone remodeling of two models of femoral cementless stems by means of DEXA and finite elements

BackgroundA hip replacement with a cemented or cementless femoral stem produces an effect on the bone called adaptive remodelling, attributable to mechanical and biological factors. All of the cementless prostheses designs try to achieve an optimal load transfer in order to avoid stress-shielding, which produces an osteopenia.Long-term densitometric studies taken after implanting ABG-I and ABG-II stems confirm that the changes made to the design and alloy of the ABG-II stem help produce less proximal atrophy of the femur. The simulation with FE allowed us to study the biomechanical behaviour of two stems. The aim of this study was, if possible, to correlate the biological and mechanical findings.MethodsBoth models with prostheses ABG-I and II have been simulated in five different moments of time which coincide with the DEXA measurements: postoperative, 6 months, 1, 3 and 5 years, in addition to the healthy femur as the initial reference. For the complete comparative analysis of both stems, all of the possible combinations of bone mass (group I and group II of pacients in two controlled studies for ABG-I and II stems, respectively), prosthetic geometry (ABG-I and ABG-II) and stem material (Wrought Titanium or TMZF) were simulated.Results and DiscussionIn both groups of bone mass an increase of stress in the area of the cancellous bone is produced, which coincides with the end of the HA coating, as a consequence of the bottleneck effect which is produced in the transmission of loads, and corresponds to Gruen zones 2 and 6, where no osteopenia can be seen in contrast to zones 1 and 7.ConclusionsIn this study it is shown that the ABG-II stem is more effective than the ABG-I given that it generates higher tensional values on the bone, due to which proximal bone atrophy diminishes. This biomechanical behaviour with an improved transmission of loads confirmed by means of FE simulation corresponds to the biological findings obtained with Dual-Energy X-Ray Absorptiometry (DEXA).

Fixation strength of biocomposite wedge interference screw in ACL reconstruction: effect of screw length and tunnel/screw ratio. A controlled laboratory study

BackgroundPrimary stability of the graft is essential in anterior cruciate ligament surgery. An optimal method of fixation should be easy to insert and provide great resistance against pull-out forces.A controlled laboratory study was designed to test the primary stability of ACL tendinous grafts in the tibial tunnel. The correlation between resistance to traction forces and the cross-section and length of the screw was studied.MethodsThe tibial phase of ACL reconstruction was performed in forty porcine tibias using digital flexor tendons of the same animal. An 8 mm tunnel was drilled in each specimen and two looped tendons placed as graft. Specimens were divided in five groups according to the diameter and length of the screw used for fixation. Wedge interference screws were used. Longitudinal traction was applied to the graft with a Servohydraulic Fatigue System. Load and displacement were controlled and analyzed.ResultsThe mean loads to failure for each group were 295,44 N (Group 1; 9 × 23 screw), 564,05 N (Group 2; 9 × 28), 614,95 N (Group 3; 9 × 35), 651,14 N (Group 4; 10 × 28) and 664,99 (Group 5; 10 × 35). No slippage of the graft was observed in groups 3, 4 and 5. There were significant differences in the load to failure among groups (ANOVA/P < 0.001).ConclusionsLonger and wider interference screws provide better fixation in tibial ACL graft fixation. Short screws (23 mm) do not achieve optimal fixation and should be implanted only with special requirements.

Applications of finite element simulation in orthopedic and trauma surgery

Research in different areas of orthopedic and trauma surgery requires a methodology that allows both a more economic approach and the ability to reproduce different situations in an easy way. Simulation models have been introduced recently in bioengineering and could become an essential tool in the study of any physiological unity, regardless of its complexity. The main problem in modeling with finite elements simulation is to achieve an accurate reproduction of the anatomy and a perfect correlation of the different structures, in any region of the human body. Authors have developed a mixed technique, joining the use of a three-dimensional laser scanner Roland Picza captured together with computed tomography (CT) and 3D CT images, to achieve a perfect reproduction of the anatomy. Finite element (FE) simulation lets us know the biomechanical changes that take place after hip prostheses or osteosynthesis implantation and biological responses of bone to biomechanical changes. The simulation models are able to predict changes in bone stress distribution around the implant, so allowing preventing future pathologies. The development of a FE model of lumbar spine is another interesting application of the simulation. The model allows research on the lumbar spine, not only in physiological conditions but also simulating different load conditions, to assess the impact on biomechanics. Different degrees of disc degeneration can also be simulated to determine the impact on adjacent anatomical elements. Finally, FE models may be useful to test different fixation systems, i.e., pedicular screws, interbody devices or rigid fixations compared with the dynamic ones. We have also developed models of lumbar spine and hip joint to predict the occurrence of osteoporotic fractures, based on densitometric determinations and specific biomechanical models, including approaches from damage and fracture mechanics. FE simulations also allow us to predict the behavior of orthopedic splints applied to the correction of deformities, providing the recovering force-displacement and angle-moment curves that characterize the mechanical behavior of the splint in the overall range of movement.

A Constitutive Model for the Annulus of Human Intervertebral Disc: Implications for Developing a Degeneration Model and Its Influence on Lumbar Spine Functioning

The study of the mechanical properties of the annulus fibrosus of the intervertebral discs is significant to the study on the diseases of lumbar intervertebral discs in terms of both theoretical modelling and clinical application value. The annulus fibrosus tissue of the human intervertebral disc (IVD) has a very distinctive structure and behaviour. It consists of a solid porous matrix, saturated with water, which mainly contains proteoglycan and collagen fibres network. In this work a mathematical model for a fibred reinforced material including the osmotic pressure contribution was developed. This behaviour was implemented in a finite element (FE) model and numerical characterization and validation, based on experimental results, were carried out for the normal annulus tissue. The characterization of the model for a degenerated annulus was performed, and this was capable of reproducing the increase of stiffness and the reduction of its nonlinear material response and of its hydrophilic nature. Finally, this model was used to reproduce the degeneration of the L4L5 disc in a complete finite element lumbar spine model proving that a single level degeneration modifies the motion patterns and the loading of the segments above and below the degenerated disc.

Development and Kinematic Verification of a Finite Element Model for the Lumbar Spine: Application to Disc Degeneration

The knowledge of the lumbar spine biomechanics is essential for clinical applications. Due to the difficulties to experiment on living people and the irregular results published, simulation based on finite elements (FE) has been developed, making it possible to adequately reproduce the biomechanics of the lumbar spine. A 3D FE model of the complete lumbar spine (vertebrae, discs, and ligaments) has been developed. To verify the model, radiological images (X-rays) were taken over a group of 25 healthy, male individuals with average age of 27.4 and average weight of 78.6 kg with the corresponding informed consent. A maximum angle of 34.40° is achieved in flexion and of 35.58° in extension with a flexion-extension angle of 69.98°. The radiological measurements were 33.94 ± 4.91°, 38.73 ± 4.29°, and 72.67°, respectively. In lateral bending, the maximum angles were 19.33° and 23.40 ± 2.39, respectively. In rotation a maximum angle of 9.96° was obtained. The model incorporates a precise geometrical characterization of several elements (vertebrae, discs, and ligaments), respecting anatomical features and being capable of reproducing a wide range of physiological movements. Application to disc degeneration (L5-S1) allows predicting the affection in the mobility of the different lumbar segments, by means of parametric studies for different ranges of degeneration.

A finite element comparison between the mechanical behaviour of rigid and resilient oral implants with respect to immediate loading

In this paper, a qualitative comparison between two types of dental implants with respect to their behaviour under immediate loading is presented. This analysis has been carried out using the finite element method. Since micromotions (and not the load) are responsible of the appearance of a fibrous interface avoiding osseointegration, the relative displacement between the bone surface and the implant has been the main variable analyzed at different loading states and for the two implant types here considered. The implants analyzed differ in their mechanical behavior: rigid or resilient. Their main difference lies in the joining between the different pieces that make up the dental system. While in the rigid implant all the pieces are screwed, in the resilient implant a relative displacement between the pieces is allowed, with the additional introduction of a silicone gasket that acts like the periodontal ligament. Both implants were considered with a similar geometry and under two different loading scenarios, one equivalent to the force of chewing applied to a molar and another which corresponds to a premolar. For the resilient implant, a hyperelastic behaviour for the silicone and contact conditions between the different mobile parts of the implant are considered. The displacements of the emerging-body in both designs are also compared with the values obtained by several authors. However, the results show that both implants fulfill the constraint of the immediate loading protocol. The micromotions of the resilient implant are lower to those of the rigid one, favouring therefore a good osseointegration process while keeping the stresses in the implant under admissible maximum values.

Influence of different fusion techniques in lumbar spine over the adjacent segments: A 3D finite element study

The most conventional technique to treat the intervertebral disc degeneration consists on fusing the affected segment with a posterior screw fixation and sometimes with the insertion of a cage in the intersomatic space. However, this kind of surgeries had controversial results in the adjacent discs. The aim of this work was to prove the stabilization of the spine and the decompression of the disc and to analyze the influence over the adjacent segments. With this purpose, four different models were built and simulated under different loading conditions. The stabilization of the spine was ensured by the screw fixation which reduced dramatically the relative motion in the affected segment. On the other hand, the pore pressure showed a high fall in the operated models proving the decompression of the neural structures. In the adjacent segments, the ROM increased up to 50% in the upper disc and 70% in the lower one. The pore pressure and principal stresses also increased after both surgeries. The observed results suggested that the fusion procedure could trigger a cascade degeneration effect over the adjacent discs, while it is also seen that cage insertion helps to maintain disc height in a better way than screw fixation only.

Densitometric and finite-element analysis of bone remodeling further to implantation of an uncemented anatomical femoral stem

Abstract Introduction Implantation of a femoral stem changes the load transmission dynamics in the hip and gives rise to the so-called adaptive remodeling. The goal pursued by all stems, whether cemented or not, is to achieve a perfect load transmission mechanism in order to avoid the phenomenon of stress-shielding, which may cause proximal bone devitalization. Materials and methods In order to quantify bone mass variations in the 7 Gruen zones, a serial DEXA analysis was carried out in 80 patients, with preoperative measurements as well as postoperative measurements at 6 months and 1, 3, 5, 7 and 10 years post implantation. Results and conclusions Finite-element (FE) simulations make it possible to characterize the biomechanical changes that occur in the femur further to implantation of a prosthetic stem, as well as the stems long-term performance. The purpose of our study is to determine whether the results of the simulation can explain the biomechanical changes that may lie behind the evolution of bone density observed through DEXA scanning after implantation of an uncemented anatomical stem. The results of the FE simulation show an excellent match between the bone loss observed on DEXA scans and the evolution of stress patterns observed in each of the Gruen zones, which confirms that even if the stem implanted was metaphyseal, stress shielding was manifest in the proximal femoral area, giving rise to the devitalization of bone in Gruen zones 1 and 7.

Estudio densitométrico y con elementos finitos de la remodelación ósea tras la implantación de un vástago femoral anatómico no cementado

Introduccion La implantacion de un vastago femoral cambia las condiciones de transmision de carga de la cadera, produciendo el denominado remodelamiento adaptativo. El objetivo de todos los vastagos (cementados y no cementados) ha sido conseguir una perfecta transmision de cargas que evite los fenomenos de puenteo de fuerzas o stressshielding, que a su vez producen una desvitalizacion osea proximal. Material y metodo Para cuantificar las variaciones de la masa osea en las 7 zonas de Gruen se ha realizado un estudio seriado a 10 anos con DEXA en 80 pacientes, con mediciones en el pre y posoperatorio, 6 meses posperatorio, y a 1, 3, 5, 7 y 10 anos tras la implantacion de la protesis. Resultados y Conclusiones La simulacion con elementos finitos (EF) permite caracterizar los cambios biomecanicos que se producen en el femur tras la implantacion de un vastago protesico, asi como su comportamiento a largo plazo. El objetivo de nuestro estudio es comprobar si los resultados de la simulacion explican los cambios biomecanicos que justifiquen la evolucion de la densidad osea obtenida mediante el estudio con DEXA, tras la implantacion de un vastago anatomico no cementado. Los resultados de la simulacion con EF presentan un perfecto paralelismo entre las perdidas de masa osea detectadas con la DEXA y la evolucion tensional en cada zona de Gruen, lo que confirma que aunque el diseno de la protesis es de apoyo metafisario, se produce un claro fenomeno de puenteo de fuerzas en la zona proximal del femur, todo lo cual produce una desvitalizacion osea en las zonas 1 y 7 de Gruen.