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Dive into the research topics where Joseph Edward Semple is active.

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Featured researches published by Joseph Edward Semple.


Archive | 1995

Aromatic heterocyclic derivatives as enzyme inhibitors

Susan Y. Tamura; Joseph Edward Semple; William C. Ripka; Robert John Ardecky; Yu Ge; Stephen H. Carpenter; Terence K. Brunck


Archive | 2002

Conjugates activated by cell surface proteases and therapeutic uses thereof

Edwin L. Madison; Joseph Edward Semple; George P. Vlasuk; Scott Jeffrey Kemp; Mallareddy Komandla; Daniel Vanna Siev


Archive | 2000

Plasminogen activator inhibitor antagonists

Edwin L. Madison; Terence K. Brunck; Joseph Edward Semple; Marguerita Lim-Wilby; Kent E. Pryor; D. Lewis Ii Ronald; David F. Duncan; C. Maxwell Lawrence


Archive | 2000

Non-covalent inhibitors of urokinase and blood vessel formation

Joseph Edward Semple; Michael I. Weinhouse; Odile Esther Levy; Edwin L. Madison; Amir P. Tamiz


Archive | 1995

3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS

Joseph Edward Semple; Robert John Ardecky; Ruth F. Nutt; William C. Ripka; David C. Rowley; Marguerita Lim-Wilby; Terence K. Brunck


Archive | 1995

3-amino-2-oxo-1-piperidineacetic derivatives containing an arginine mimic as enzyme inhibitors

Joseph Edward Semple; Odile E. Levy; Ruth F. Nutt; William C. Ripka


Archive | 2005

Trisubstituted nitrogen modulators of tyrosine phosphatases

Joseph Edward Semple; Darryl Rideout; Ruth F. Nutt; Mark D. Shenderovich; Jing Wang; Shankari Mylvaganam; Feiyue Wu; Chung Ying Tsai; Venkatachalapathi V. Yalamoori; Colin J. Loweth


Archive | 2007

Indole-benzimidazole and indazole inhibitors of tyrosine phosphatases

Darryl Rideout; Venkatachalapathi V. Yalamoori; Chung Y. Tsai; Zacharia S. Cheruvallath; Vasanthakumar Rajappan; Joseph Edward Semple


Archive | 2000

Plasminogen activator inhibitor antagonists related applications

Edwin L. Madison; Terence K. Brunck; Joseph Edward Semple; Marguerita Lim-Wilby; Kent E. Pryor; Ronald D. Ii Lewis; David F. Duncan; C. Maxwell Lawrence


Archive | 2006

2-Imidazolone and 2-Imidazolidinone Heterocyclic Inhibitors of Tyrosine Phosphatases

Zacharia S. Cheruvallath; Joseph Edward Semple; Vasanthakumar Rajappan; Darryl Rideout; Venkatachalapathi V. Yalamoori; Chung-Ying Tsai; Feiyue Wu; Lars Thoresen; Mark D. Shenderovich

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