Joshua M. Polster

Quantitative analysis of glenoid bone loss in osteoarthritis using three-dimensional computed tomography scans

The 3-dimensional (3D) shape of the glenoid vault has been defined previously and shown to be a complex, yet consistent, shape in individuals without glenoid pathology. We proposed assessing whether this conserved shape could be used as a template to measure glenoid bone loss in subjects with glenohumeral osteoarthritis. Computed tomography (CT) scans of both shoulders were obtained from 12 subjects with unilateral glenohumeral osteoarthritis. The paired scapulae were reconstructed 3-dimensionally, using a previously developed graphic software package. Two methods of estimating glenoid bone loss were performed. First, using the software, a stereolithography model of the standardized vault shape was implanted into each glenoid and measurements made of the volume of the implant not contained within each vault. Second, direct measurements of the paired glenoid vault volumes were performed. The volume of the nonarthritic glenoid was used as a subject-specific template for normal glenoid vault volume for each pair. The glenoid bone volumes measured by each method were compared and Pearsons correlation coefficient determined. The average measurement of glenoid bone loss using the vault implant was within 0.8% (SD +/- 1.5%) of the measurement made using the contralateral, normal glenoid. For all patients, Pearsons correlation coefficient was .99, indicating a very high correlation between the two methods of measuring bone loss (P < .0001). The intricate, yet consistent 3D shape of the glenoid vault can be used as an accurate and reliable template to measure glenoid bone loss in glenohumeral osteoarthritis.

MRI of the Knee Ligaments and Menisci: Comparison of Isotropic-Resolution 3D and Conventional 2D Fast Spin-Echo Sequences at 3 T

OBJECTIVE The purpose of this study was to evaluate the diagnostic performance of sampling perfection with application-optimized contrasts using different flip-angle evolutions (SPACE) 3D fast spin-echo acquisition relative to conventional 2D fast spin-echo acquisition in the 3-T MRI evaluation of the menisci and ligaments of the knee. MATERIALS AND METHODS Images from all MRI knee examinations performed with a single 3-T system from September 2008 to January 2009 were reviewed. Seventy-one examinations of patients who subsequently underwent knee arthroscopy and an additional 29 examinations of patients who did not undergo surgery were selected for a total of 100 examinations. All imaging was performed with multiplanar conventional 2D and SPACE 3D fast spin-echo acquisitions. Six musculoskeletal radiologists independently reviewed the images. Area under the receiver operating characteristic (ROC) curve was calculated for the menisci and anterior cruciate ligament with arthroscopy as the reference standard. Disagreement between the two acquisitions was calculated for the posterior cruciate ligament and medial and lateral collateral ligaments. The Wilcoxon signed rank test was used to compare each readers confidence scores for the two techniques. RESULTS For the medial meniscus, the average area under the ROC curve was statistically significantly larger (p = 0.01) with the conventional 2D (0.931) than with the SPACE 3D (0.893) technique. Average confidence in diagnosing medial meniscal tears also was statistically significantly greater with the 2D than with the 3D technique (p = 0.001). No statistically significant differences were found for the lateral meniscus or anterior cruciate ligament. The rate of discordance between findings with the 2D and 3D techniques was low for the posterior cruciate ligament and medial and lateral collateral ligaments (range, 4.2-5.7%). CONCLUSION In evaluation of menisci with 3-T MRI, readers performed better with conventional 2D acquisition than with SPACE 3D acquisition. In evaluation of ligaments, the readers had similar performance with the two acquisition methods.

Relationship Between Humeral Torsion and Injury in Professional Baseball Pitchers

Background: High levels of humeral torsion allow baseball pitchers to achieve maximum external rotation in the late cocking phase of pitching with lower twisting and shear forces on the long head of the biceps tendon and rotator cuff tendons. Hypothesis: Humeral torsion is inversely related to the incidence and severity of shoulder injuries and other upper extremity injuries in professional baseball pitchers. Study Design: Case-control study; Level of evidence, 3. Methods: A total of 25 professional pitchers from a single Major League Baseball organization were prospectively recruited into this study. Computed tomography (CT) was performed on dominant and nondominant humeri, and image data were processed with a 3-dimensional volume-rendering postprocessing program. The software program was then modified to model a simplified throwing motion and to measure potential internal impingement distances in a small subset of players. Players were followed for 2 years after CT, and the number of days missed from pitching activities was recorded as a measure of injury severity and incidence. Results: The mean dominant humeral torsion was 38.5° ± 8.9°; the mean nondominant humeral torsion was 27.6° ± 8.0°. The difference between dominant and nondominant torsions was significant (P < .0001). Among the 11 pitchers (44%) injured during follow-up, 5 players had shoulder injuries, 7 had elbow injuries, and 2 had finger injuries. Dominant humeral torsion was a statistically significant predictor of severe injuries (≥30 days; P = .048) but not of milder injuries. Among injured players, higher numbers of days missed because of injury were strongly correlated with lower degrees of dominant humeral torsion (r = −0.78; P = .005) and smaller differences between dominant and nondominant humeral torsions (r = −0.59; P = .055). There was no significant association between the incidence of shoulder injury and minimum glenoid-tuberosity distance in the dominant or nondominant shoulder or degree of dominant glenoid version. Conclusion: A strong relationship was found between lower degrees of dominant humeral torsion and more severe upper extremity injuries as well as a trend relating lower side-to-side differences in torsion with more severe dominant upper extremity injuries. In addition, there was a higher incidence of severe injuries in players with lower degrees of dominant torsion. If future studies confirm these results, humeral torsion measurements could play a role in risk assessment in pitchers.

MRI and gross anatomy of the iliopsoas tendon complex

ObjectiveThe objective was to explain the anatomic basis of a longitudinal cleft of increased signal in the iliopsoas tendon seen on hip MR arthrograms.Materials and methodsA prospective review of 20 MR hip arthrograms was performed using standard and fat-suppressed T1-weighted images to establish whether or not the cleft was composed of fatty tissue and to define the anatomy of the iliopsoas tendon complex. Three cadaver dissections of the hip region were then performed for anatomic correlation.ResultsFourteen out of 20 MR hip arthrograms demonstrated a longitudinal cleft of increased T1 signal adjacent to the iliopsoas tendon, which suppressed on frequency selective fat-suppressed images, indicating fatty composition. Gross anatomic correlation demonstrated this fatty cleft to represent a fascial plane adjacent to the iliopsoas tendon, in one case separating the iliopsoas tendon medially from a thin intramuscular tendon within the lateral portion of the iliacus muscle. Also noted was a direct muscular insertion of the lateral portion of the iliacus muscle onto the anterior portion of the proximal femoral diaphysis in all 3 cadavers.ConclusionThe anatomy of the iliopsoas tendon complex is more complicated than typically illustrated and includes the iliopsoas tendon itself attaching to the lesser trochanter, the lateral portion of the iliacus muscle attaching directly upon the anterior portion of the proximal femoral diaphysis, and a thin intramuscular tendon within this lateral iliacus muscle that is separated from the iliopsoas tendon by a cleft of fatty fascia that accounts for the MRI findings of a cleft of increased T1 signal.

Failure With Continuity in Rotator Cuff Repair “Healing”

Background: Ten to seventy percent of rotator cuff repairs form a recurrent defect after surgery. The relationship between retraction of the repaired tendon and formation of a recurrent defect is not well defined. Purpose/Hypotheses: To measure the prevalence, timing, and magnitude of tendon retraction after rotator cuff repair and correlate these outcomes with formation of a full-thickness recurrent tendon defect on magnetic resonance imaging, as well as clinical outcomes. We hypothesized that (1) tendon retraction is a common phenomenon, although not always associated with a recurrent defect; (2) formation of a recurrent tendon defect correlates with the timing of tendon retraction; and (3) clinical outcome correlates with the magnitude of tendon retraction at 52 weeks and the formation of a recurrent tendon defect. Study Design: Case series; Level of evidence, 4. Methods: Fourteen patients underwent arthroscopic rotator cuff repair. Tantalum markers placed within the repaired tendons were used to assess tendon retraction by computed tomography scan at 6, 12, 26, and 52 weeks after operation. Magnetic resonance imaging was performed to assess for recurrent tendon defects. Shoulder function was evaluated using the Penn score, visual analog scale (VAS) score for pain, and isometric scapular-plane abduction strength. Results: All rotator cuff repairs retracted away from their position of initial fixation during the first year after surgery (mean [standard deviation], 16.1 [5.3] mm; range, 5.7-23.2 mm), yet only 30% of patients formed a recurrent defect. Patients who formed a recurrent defect tended to have more tendon retraction during the first 6 weeks after surgery (9.7 [6.0] mm) than those who did not form a defect (4.1 [2.2] mm) (P = .08), but the total magnitude of tendon retraction was not significantly different between patient groups at 52 weeks. There was no significant correlation between the magnitude of tendon retraction and the Penn score (r = 0.01, P = .97) or normalized scapular abduction strength (r = −0.21, P = .58). However, patients who formed a recurrent defect tended to have lower Penn scores at 52 weeks (P = .1). Conclusion: Early tendon retraction, but not the total magnitude, correlates with formation of a recurrent tendon defect and worse clinical outcomes. “Failure with continuity” (tendon retraction without a recurrent defect) appears to be a common phenomenon after rotator cuff repair. These data suggest that repairs should be protected in the early postoperative period and repair strategies should endeavor to mechanically and biologically augment the repair during this critical early period.

Postoperative Single-Fraction Radiation for Prevention of Heterotopic Ossification of the Elbow

PURPOSE Heterotopic ossification (HO) about the elbow has been described after surgery, trauma, and burns. Even limited deposits can lead to significant functional deficits. Little data exist regarding outcomes of patients treated with radiation therapy (RT) after elbow surgery. We report here the Cleveland Clinic experience with single-fraction radiation following surgery to the elbow. The primary endpoint was the rate of new HO after RT. Secondary endpoints were range of motion, functional compromise, and toxicity. METHODS AND MATERIALS From May 1993 to July 2006, 36 patients underwent elbow surgery followed by single-fraction RT. Range of motion data were collected before and during surgery and at last follow-up. Radiographs were reviewed for persistent or new HO. Patient and treatment factors were analyzed for correlation with development of HO or functional compromise. RESULTS Median follow-up was 8.7 months, median age was 42 years, and 75% of patients were male. Twenty-six (72%) patients had HO prior to surgery. All patients had significant limitations in flexion/extension or pronation/supination at baseline. Thirty-one (86%) patients had prior elbow trauma, and 26 (72%) patients had prior surgery. RT was administered a median of 1 day postoperatively (range, 1-4 days). Thirty-four patients received 700 cGy, and 2 patients received 600 cGy. Three (8%) patients developed new HO after RT. All patients had improvement in range of motion from baseline. No patient or treatment factors were significantly associated with the development of HO or functional compromise. CONCLUSIONS Single-fraction RT after surgery to the elbow is associated with favorable functional and radiographic outcomes.

Accuracy of MRI in the Diagnosis of Meniscal Tears in Older Patients

OBJECTIVE The objective of our study was to determine the accuracy of MRI in diagnosing meniscal tears in older patients and the frequency with which abnormal MRI findings correlate with degeneration, fraying, and tears at arthroscopy. MATERIALS AND METHODS Ninety-two patients 50 years old or older who had undergone knee MRI followed by knee arthroscopy within 6 months were selected. Menisci were graded on a 5-point scale: 1, definitely no tear; 2, probably no tear; 3, indeterminate or equivocal; 4, probably a tear; and 5, definitely a tear. Meniscal signal changes, meniscal surface morphology, and extrameniscal abnormalities were noted. Operative notes were reviewed, and the sensitivity and specificity of MRI results were calculated. RESULTS For medial tears, MRI had a sensitivity and specificity of 0.91 and 0.94, respectively, when grade 5 was considered a tear, 0.96 and 0.76 when grades 4 and 5 were considered a tear, and 0.99 and 0.47 when grades 3-5 were considered a tear. For lateral tears, MRI had a sensitivity and specificity of 0.73 and 0.91 when grade 5 was considered a tear, 0.88 and 0.80 when grades 4 and 5 were considered a tear, and 1.0 and 0.61 when grades 3-5 were considered a tear. The positive predictive values (PPVs) of MRI for the medial meniscus were 99%, grade 5; 57%, grade 4; 29%, grade 3; 25%, grade 2; and 0%, grade 1. For the lateral meniscus, the PPVs of MRI were 76%, grade 5; 36%, grade 4; 19%, grade 3; and 0%, grades 1 and 2. CONCLUSION The accuracy of MRI for diagnosing meniscal tears in older patients is high and similar to that in younger patients when only definitive findings are considered a tear. The specificity decreases if equivocal or probable findings are considered a tear.

Imaging of Arthroplasties: Improved Image Quality and Lesion Detection With Iterative Metal Artifact Reduction, a New CT Metal Artifact Reduction Technique.

OBJECTIVE The purpose of this study was to compare iterative metal artifact reduction (iMAR), a new single-energy metal artifact reduction technique, with filtered back projection (FBP) in terms of attenuation values, qualitative image quality, and streak artifacts near shoulder and hip arthroplasties and observer ability with these techniques to detect pathologic lesions near an arthroplasty in a phantom model. MATERIALS AND METHODS Preoperative and postoperative CT scans of 40 shoulder and 21 hip arthroplasties were reviewed. All postoperative scans were obtained using the same technique (140 kVp, 300 quality reference mAs, 128 × 0.6 mm detector collimation) on one of three CT scanners and reconstructed with FBP and iMAR. The attenuation differences in bones and soft tissues between preoperative and postoperative scans at the same location were compared; image quality and streak artifact for both reconstructions were qualitatively graded by two blinded readers. Observer ability and confidence to detect lesions near an arthroplasty in a phantom model were graded. RESULTS For both readers, iMAR had more accurate attenuation values (p < 0.001), qualitatively better image quality (p < 0.001), and less streak artifact (p < 0.001) in all locations near arthroplasties compared with FBP. Both readers detected more lesions (p ≤ 0.04) with higher confidence (p ≤ 0.01) with iMAR than with FBP in the phantom model. CONCLUSION The iMAR technique provided more accurate attenuation values, better image quality, and less streak artifact near hip and shoulder arthroplasties than FBP; iMAR also increased observer ability and confidence to detect pathologic lesions near arthroplasties in a phantom model.

Rheumatoid Arthritis: Evaluation with Contrast-enhanced CT with Digital Bone Masking

The purpose of this HIPAA-compliant study was to prospectively evaluate the feasibility of contrast material-enhanced computed tomography (CT) with digital bone masking for the evaluation of synovitis and tenosynovitis in patients with rheumatoid arthritis. Four patients with rheumatoid arthritis and findings at magnetic resonance (MR) imaging were evaluated after informed consent for this institutional review board-approved study was obtained. To improve the conspicuity of synovial enhancement, postcontrast CT was performed with a relatively low kilovoltage and high iodine concentration and precontrast images were used as a subtraction mask to eliminate high-attenuation cortical bone contours. Moderate to high agreement between CT and MR imaging findings for synovitis and tenosynovitis was demonstrated, which suggests that this technique may be an acceptable alternative to MR imaging in the evaluation of rheumatoid arthritis.

Comparison of MR arthrography with arthroscopy of the hip for the assessment of intra-articular loose bodies

ObjectiveTo assess the specificity and sensitivity of MR arthrography of the hip in comparison with arthroscopy for the evaluation of intra-articular loose bodies.DesignOver a 3-year period, 81 consecutive patients underwent a total of 82 hip arthroscopies by a single orthopedic surgeon for intractable hip pain. Of the 82 arthroscopies, 70 had pre-operative MR arthrograms. Of these, 57 were available for retrospective review, after which they were compared with the operative notes of the subsequent arthroscopies.ResultsOf 82 arthroscopies 16 (20%) demonstrated intra-articular loose bodies, while, in the study group, nine of 57 had loose bodies (16%). There was a total of seven discordant cases (five false negatives and two false positives). The sensitivity of MR arthrography for detection of intra-articular loose bodies was 44%, while the specificity was 96%.ConclusionWhile the specificity of MR arthrography for the detection of intra-articular loose bodies was high (96%), the sensitivity was not nearly as good (44%).