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Featured researches published by Naveen Subhas.


American Journal of Roentgenology | 2011

MRI of the Knee Ligaments and Menisci: Comparison of Isotropic-Resolution 3D and Conventional 2D Fast Spin-Echo Sequences at 3 T

Naveen Subhas; Amy W. Kao; Maxime Freire; Joshua M. Polster; Nancy A. Obuchowski; Carl S. Winalski

OBJECTIVE The purpose of this study was to evaluate the diagnostic performance of sampling perfection with application-optimized contrasts using different flip-angle evolutions (SPACE) 3D fast spin-echo acquisition relative to conventional 2D fast spin-echo acquisition in the 3-T MRI evaluation of the menisci and ligaments of the knee. MATERIALS AND METHODS Images from all MRI knee examinations performed with a single 3-T system from September 2008 to January 2009 were reviewed. Seventy-one examinations of patients who subsequently underwent knee arthroscopy and an additional 29 examinations of patients who did not undergo surgery were selected for a total of 100 examinations. All imaging was performed with multiplanar conventional 2D and SPACE 3D fast spin-echo acquisitions. Six musculoskeletal radiologists independently reviewed the images. Area under the receiver operating characteristic (ROC) curve was calculated for the menisci and anterior cruciate ligament with arthroscopy as the reference standard. Disagreement between the two acquisitions was calculated for the posterior cruciate ligament and medial and lateral collateral ligaments. The Wilcoxon signed rank test was used to compare each readers confidence scores for the two techniques. RESULTS For the medial meniscus, the average area under the ROC curve was statistically significantly larger (p = 0.01) with the conventional 2D (0.931) than with the SPACE 3D (0.893) technique. Average confidence in diagnosing medial meniscal tears also was statistically significantly greater with the 2D than with the 3D technique (p = 0.001). No statistically significant differences were found for the lateral meniscus or anterior cruciate ligament. The rate of discordance between findings with the 2D and 3D techniques was low for the posterior cruciate ligament and medial and lateral collateral ligaments (range, 4.2-5.7%). CONCLUSION In evaluation of menisci with 3-T MRI, readers performed better with conventional 2D acquisition than with SPACE 3D acquisition. In evaluation of ligaments, the readers had similar performance with the two acquisition methods.


Journal of Bone and Joint Surgery, American Volume | 2015

Three-Dimensional Imaging and Templating Improve Glenoid Implant Positioning

Joseph P. Iannotti; Scott Weiner; Eric Rodriguez; Naveen Subhas; Thomas E. Patterson; Bong Jae Jun; Eric T. Ricchetti

BACKGROUND Preoperative quantitative assessment of glenoid bone loss, selection of the glenoid component, and definition of its desired location can be challenging. Placement of the glenoid component in the desired location at the time of surgery is difficult, especially with severe glenoid pathological conditions. METHODS Forty-six patients were randomly assigned to three-dimensional computed tomographic preoperative templating with either standard instrumentation or with patient-specific instrumentation and were compared with a nonrandomized group of seventeen patients with two-dimensional imaging and standard instrumentation used as historical controls. All patients had postoperative three-dimensional computed tomographic metal artifact reduction imaging to measure and to compare implant position with the preoperative plan. RESULTS Using three-dimensional imaging and templating with or without patient-specific instrumentation, there was a significant improvement achieving the desired implant position within 5° of inclination or 10° of version when compared with two-dimensional imaging and standard instrumentation. CONCLUSION Three-dimensional assessment of glenoid anatomy and implant templating and the use of these images at the time of surgery improve the surgeons ability to place the glenoid implant in the desired location.


Radiologic Clinics of North America | 2015

Metal Artifact Reduction: Standard and Advanced Magnetic Resonance and Computed Tomography Techniques

Amit Gupta; Naveen Subhas; Andrew N. Primak; Mathias Nittka; Kecheng Liu

An increasing number of joint replacements are being performed in the United States. Patients undergoing these procedures can have various complications. Imaging is one of the primary means of diagnosing these complications. Cross-sectional imaging techniques, such as computed tomography (CT) and MR imaging, are more sensitive than radiographs for evaluating complications. The use of CT and MR imaging in patients with metallic implants is limited by the presence of artifacts. This review discusses the causes of metal artifacts on MR imaging and CT, contributing factors, and conventional and novel methods to reduce the effects of these artifacts on scans.


American Journal of Roentgenology | 2012

Accuracy of MRI in the Diagnosis of Meniscal Tears in Older Patients

Naveen Subhas; Flavia A. Sakamoto; Michael W. Mariscalco; Joshua M. Polster; Nancy A. Obuchowski; Morgan H. Jones

OBJECTIVE The objective of our study was to determine the accuracy of MRI in diagnosing meniscal tears in older patients and the frequency with which abnormal MRI findings correlate with degeneration, fraying, and tears at arthroscopy. MATERIALS AND METHODS Ninety-two patients 50 years old or older who had undergone knee MRI followed by knee arthroscopy within 6 months were selected. Menisci were graded on a 5-point scale: 1, definitely no tear; 2, probably no tear; 3, indeterminate or equivocal; 4, probably a tear; and 5, definitely a tear. Meniscal signal changes, meniscal surface morphology, and extrameniscal abnormalities were noted. Operative notes were reviewed, and the sensitivity and specificity of MRI results were calculated. RESULTS For medial tears, MRI had a sensitivity and specificity of 0.91 and 0.94, respectively, when grade 5 was considered a tear, 0.96 and 0.76 when grades 4 and 5 were considered a tear, and 0.99 and 0.47 when grades 3-5 were considered a tear. For lateral tears, MRI had a sensitivity and specificity of 0.73 and 0.91 when grade 5 was considered a tear, 0.88 and 0.80 when grades 4 and 5 were considered a tear, and 1.0 and 0.61 when grades 3-5 were considered a tear. The positive predictive values (PPVs) of MRI for the medial meniscus were 99%, grade 5; 57%, grade 4; 29%, grade 3; 25%, grade 2; and 0%, grade 1. For the lateral meniscus, the PPVs of MRI were 76%, grade 5; 36%, grade 4; 19%, grade 3; and 0%, grades 1 and 2. CONCLUSION The accuracy of MRI for diagnosing meniscal tears in older patients is high and similar to that in younger patients when only definitive findings are considered a tear. The specificity decreases if equivocal or probable findings are considered a tear.


American Journal of Roentgenology | 2016

Imaging of Arthroplasties: Improved Image Quality and Lesion Detection With Iterative Metal Artifact Reduction, a New CT Metal Artifact Reduction Technique.

Naveen Subhas; Joshua M. Polster; Nancy A. Obuchowski; Andrew N. Primak; F Dong; Brian R. Herts; Joseph P. Iannotti

OBJECTIVE The purpose of this study was to compare iterative metal artifact reduction (iMAR), a new single-energy metal artifact reduction technique, with filtered back projection (FBP) in terms of attenuation values, qualitative image quality, and streak artifacts near shoulder and hip arthroplasties and observer ability with these techniques to detect pathologic lesions near an arthroplasty in a phantom model. MATERIALS AND METHODS Preoperative and postoperative CT scans of 40 shoulder and 21 hip arthroplasties were reviewed. All postoperative scans were obtained using the same technique (140 kVp, 300 quality reference mAs, 128 × 0.6 mm detector collimation) on one of three CT scanners and reconstructed with FBP and iMAR. The attenuation differences in bones and soft tissues between preoperative and postoperative scans at the same location were compared; image quality and streak artifact for both reconstructions were qualitatively graded by two blinded readers. Observer ability and confidence to detect lesions near an arthroplasty in a phantom model were graded. RESULTS For both readers, iMAR had more accurate attenuation values (p < 0.001), qualitatively better image quality (p < 0.001), and less streak artifact (p < 0.001) in all locations near arthroplasties compared with FBP. Both readers detected more lesions (p ≤ 0.04) with higher confidence (p ≤ 0.01) with iMAR than with FBP in the phantom model. CONCLUSION The iMAR technique provided more accurate attenuation values, better image quality, and less streak artifact near hip and shoulder arthroplasties than FBP; iMAR also increased observer ability and confidence to detect pathologic lesions near arthroplasties in a phantom model.


American Journal of Roentgenology | 2008

MRI evaluation of costal cartilage injuries.

Naveen Subhas; Mitchell J. Kline; Michael J. Moskal; Lawrence M. White; Michael P. Recht

OBJECTIVE The usefulness of MRI in costal cartilage injuries has not been shown. We report the MRI findings in a series of patients with costal cartilage injuries. CONCLUSION MRI can be a useful technique in the diagnosis of costal cartilage injuries.


Magnetic Resonance Imaging Clinics of North America | 2011

MR Imaging of the Articular Cartilage of the Knee and Ankle

Michael C. Forney; Naveen Subhas; Brian G. Donley; Carl S. Winalski

Cartilage abnormalities in the knee and ankle are a common source of pain and are often difficult to diagnose clinically or radiographically. MR imaging is a valuable tool for diagnosing and characterizing cartilage lesions of both the knee and ankle. An understanding of the appearance of cartilage, and an understanding of how and when to report cartilage injury in the knee and ankle based on current grading systems allows the radiologist to provide the most helpful reports to referring clinicians. This article presents the range of cartilage pathologies in the knee and ankle and provides clinically relevant guidelines.


Skeletal Radiology | 2008

Glenoid labrum ossification and mechanical restriction of joint motion: extraosseous manifestations of melorheostosis

Naveen Subhas; Murali Sundaram; Thomas W. Bauer; W. H. Seitz; Michael P. Recht

We report a case of a 47-year-old man who presented with progressive loss of motion and pain in the right shoulder. Radiographs of the shoulder demonstrated dense ossification in the glenoid and humeral head with extension into the periarticular soft tissues. CT and MRI scans confirmed the radiographic findings and also revealed ossification of the glenoid labrum. A radiographic diagnosis of melorheostosis, an uncommon benign sclerosing bone dysplasia, was made. Because of the patient’s severe symptomatology, he underwent total shoulder arthroplasty. Histological analysis of the resected masses was consistent with melorheostosis with a few areas covered by a cartilage cap. This case illustrates several uncommon but important features of melorheostosis, including mechanical obstruction of joint motion requiring joint replacement, ossification of the glenoid labrum, and cartilage-covering portions of the intra-articular masses, not to be confused with cartilage-producing tumors.


Radiology | 2017

Diagnosis of Superior Labrum Anterior-to-Posterior Tears by Using MR Imaging and MR Arthrography: A Systematic Review and Meta-Analysis

John S. Symanski; Naveen Subhas; James S. Babb; Joseph Nicholson; Soterios Gyftopoulos

Purpose To evaluate the diagnostic accuracies of nonenhanced magnetic resonance (MR) imaging and MR arthrography for diagnosis of superior labrum anterior-to-posterior (SLAP) tears by using a systematic review and meta-analysis. Materials and Methods A comprehensive literature search was performed on the two main concepts of MR imaging (MR imaging, and direct and indirect MR arthrography) and SLAP tears. Inclusion criteria consisted of original studies that assessed the diagnostic accuracy of MR imaging, direct MR arthrography, and/or indirect MR arthrography for the detection of SLAP tears, by using surgical findings as the reference standard. The Quality Assessment of Diagnostic Accuracy Studies 2, or QUADAS-2 Quality Assessment of Diagnostic Accuracy Studies 2 Quality Assessment of Diagnostic Accuracy Studies 2 , tool was used to assess methodologic quality. Meta-analyses were performed that compared MR imaging studies to direct MR arthrography studies and indirect MR arthrography studies, 3-T studies to 1.5-T studies, and low-bias MR imaging studies to low-bias direct MR arthrography studies. Study variation was analyzed by using the Cochran Q test of heterogeneity and the I2 statistic. Results Thirty-two studies met inclusion and exclusion criteria, including 3524 imaging examinations: 1963 direct MR arthrography examinations (23 studies), 1402 MR examinations (14 studies), and 159 indirect MR arthrography examinations (three studies). Twelve studies had low risk for bias, two had questionable risk, and 18 had high risk. Mean sensitivities of direct MR arthrography, MR imaging, and indirect MR arthrography for SLAP tear diagnosis were 80.4%, 63.0%, and 74.2%, respectively. Mean specificities of direct MR arthrography, MR imaging, and indirect MR arthrography were 90.7%, 87.2%, and 66.5%, respectively. Summary receiver operator characteristic (ROC) curve demonstrated superior accuracy of direct MR arthrography compared with those of MR imaging and indirect MR arthrography. Similar findings were observed in the low-bias subanalysis. Summary ROC curve demonstrated overall superiority of 3-T imaging, with or without intra-articular contrast material compared with 1.5-T imaging, with or without intra-articular contrast material. Significant variance was observed for MR imaging and direct MR arthrography (P < .001) studies for both mean sensitivity and specificity. Conclusion Direct MR arthrography appears to be more accurate than nonenhanced MR imaging for diagnosis of SLAP tears, whereas 3-T MR imaging with or without intra-articular contrast material appears to improve diagnostic accuracy compared with 1.5-T MR imaging with or without intra-articular contrast material.


Skeletal Radiology | 2015

Pseudocyclops: two cases of ACL graft partial tears mimicking cyclops lesions on MRI

Claus Simpfendorfer; Anthony Miniaci; Naveen Subhas; Carl S. Winalski; Hakan Ilaslan

Arthroscopic reconstruction of the anterior cruciate ligament (ACL) using autografts or allografts is a common surgical procedure, particularly in young athletes. Although the procedure has excellent success rates, complications such as mechanical impingement, graft rupture, and arthrofibrosis can occur, often necessitating additional surgery. Magnetic resonance (MR) imaging has become a valuable tool in evaluating complications after ACL reconstruction. We report two cases of ACL reconstruction complicated by arthroscopically proven partial graft tears. In both cases the torn anterior graft fibers were flipped into the intercondylar notch, mimicking anterior arthrofibrosis, i.e., a “cyclops lesion,” on MR imaging. Careful review of the direction of graft fibers on MR imaging in the “pseudocyclops” lesions can help differentiate these partial tears from the fibrosis of a true cyclops. The “pseudocyclops” lesion is a previously undescribed MR imaging sign of partial ACL graft tear. Larger studies are required to determine the sensitivity and specificity of the sign, as well as the clinical importance of these partial graft tears.

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Bong Jae Jun

University of California

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