Juan Carlos Monllau

Surgical treatment for early osteoarthritis. Part II: allografts and concurrent procedures

Young patients with early osteoarthritis (OA) represent a challenging population due to a combination of high functional demands and limited treatment options. Conservative measures such as injection and physical therapy can provide short-term pain relief but are only palliative in nature. Joint replacement, a successful procedure in the older population, is controversial in younger patients, who are less satisfied and experience higher failure rates. Therefore, while traditionally not indicated for the treatment of OA, cartilage repair has become a focus of increased interest due to its potential to provide pain relief and alter the progression of degenerative disease, with the hope of delaying or obviating the need for joint replacement. The field of cartilage repair is seeing the rapid development of new technologies that promise greater ease of application, less demanding rehabilitation and better outcomes. Concurrent procedures such as meniscal transplantation and osteotomy, however, remain of crucial importance to provide a normalized biomechanical environment for these new technologies.Level of evidenceSystematic review, Level II.

Suture-Only Fixation Technique Leads to a Higher Degree of Extrusion Than Bony Fixation in Meniscal Allograft Transplantation

Background: Most of the published series of transplanted menisci have consistently shown some degree of allograft extrusion. The speculation is that this meniscal extrusion may be caused by the soft tissue technique used to fix the allograft. Hypothesis: The percentage of extruded meniscal graft would be higher if the allograft were only fixed with sutures rather than with associated bony fixation. Study Design: Cohort study; Level of evidence, 2. Methods: We performed a prospective series of 88 meniscal allograft transplantations. Thirty-three of the grafts were fixed with the suture-only technique (group A). The remaining 55 cases were performed with the bone plug method (group B). All patients were studied with magnetic resonance imaging (MRI) at a minimum 3 years’ follow-up to determine the degree of meniscal extrusion. The time between surgery and MRI evaluation was 40 months (range, 36-48 months) in both groups. Meniscal extrusion was measured on coronal MRI. The percentage of the meniscal body width that was extruded was calculated. The average percentage of extrusion for each group was compared. The Lysholm score was analyzed in relation to the fixation method and degree of meniscal extrusion. Tears of the allograft that required surgical intervention were also reported. Results: The average percentage of meniscal tissue extruded in group A was 36.3% ± 13.7% without differences between the medial (35.9% ± 18.1%) and lateral (38.3% ± 14.4%) compartments (P = .84). Group B had a mean 28.13% ± 12.2% of the meniscal body extruded without differences between the medial (25.8% ± 16.2%) and lateral (30.14% ± 13.5%) compartments. A higher percentage of extruded meniscal tissue was found in group A than in group B (P < .001). No association between the degree of meniscal extrusion and the functional score was observed (P = .4). Graft tears were observed in 21.4% of the cases in group A and in 7.3% of the cases in group B (P = .09). Conclusion: A meniscal allograft fixed with the suture-only technique showed a significantly higher degree of extruded meniscal body than that fixed with the bony fixation method, with no influence on the functional outcome. There was also a considerably higher rate of graft tears observed in those menisci fixed only with sutures, although this difference was not statistically significant with the numbers available.

Meniscal Allograft Transplantation Without Bone Blocks: A 5- to 8-Year Follow-Up of 33 Patients

PURPOSE The purpose of this study was to evaluate the functional and radiographic results on a midterm basis, as well as complications, in an initial series of meniscal allograft transplantations performed with suture fixation without any bone block. METHODS A series of 33 meniscal allograft transplantations were performed at our institution from January 2001 to October 2003. Inclusion criteria were patients with compartmental joint line pain due to a previous meniscectomy. There were 24 men and 9 women with a mean age of 38.8 years (range, 21 to 54 years). The functional outcomes were evaluated by use of Lysholm and Tegner scores at a mean and minimum follow-up of 6.5 years and 5 years, respectively. A visual analog scale for pain was also used. Radiographic assessment included joint space narrowing on the Rosenberg view and magnetic resonance imaging evaluation. RESULTS The Lysholm and Tegner scores significantly improved from 65.4 to 88.6 (P < .001) and from 3.1 to 5.5 (P < .001), respectively, after surgery. The visual analog scale score significantly dropped from 6.4 to 1.5 (P < .001). The radiographic evaluation did not show any joint space narrowing (P = .38). Meniscal extrusion was a constant finding, averaging 36.3% of total meniscal size. According to the Van Arkel criteria, the survival rate was 87.8% at 6.5 years. The rate of complications was 33%. CONCLUSIONS This study suggests that this procedure provides significant pain relief and functional improvement in selected symptomatic individuals on a midterm basis. However, there was a high rate of complications (33%) and revision surgery. LEVEL OF EVIDENCE Level IV, therapeutic case series.

Effectiveness of a Footprint Guide to Establish an Anatomic Femoral Tunnel in Anterior Cruciate Ligament Reconstruction: Computed Tomography Evaluation in a Cadaveric Model

PURPOSE To compare drilling the femoral tunnel with an offset aimer and BullsEye guide (ConMed Linvatec, Largo, FL) to perform an anatomic single-bundle reconstruction of the anterior cruciate ligament (ACL) through the anteromedial portal. METHODS Seven matched pairs of cadaveric knees were studied. The intent was to drill the femoral tunnel anatomically in all cases. In group A the femoral tunnel was drilled arthroscopically with an offset aimer. In group B the femoral tunnel was drilled arthroscopically with the BullsEye guide. Two tunnels were drilled through the same entry point in each knee. One was done at 110° of knee flexion and the other at 130°. They were scanned by computed tomography and reconstructed 3-dimensionally. Volume-rendering software was used to document relations of the drilled tunnel to the bony anatomy and tunnel length. RESULTS In group B the femoral tunnel was placed at the center of the femoral insertion site. The center of the tunnel was 9.4 mm from the high cartilage margin and 8.6 mm from the low cartilage margin. In group A the tunnels were placed deeper (5.4 mm and 12.6 mm, respectively) (P = .018). There were no differences in tunnel length for either knee flexion degree. Three of the tunnels drilled at 110° in group A compromised the posterior tunnel wall and measured less than 25 mm in length. CONCLUSIONS Accurate placement in the center of the femoral footprint of the ACL is better accomplished with the BullsEye guide rather than 5-mm offset aimers. Five-millimeter offset aimers might cause posterior tunnel blowout and present the risk of obtaining short tunnels when performing oblique femoral tunnel placement through the anteromedial portal at 110° of knee flexion. CLINICAL RELEVANCE The BullsEye guide might be better than standard offset aimers in the performance of anatomic single-bundle ACL reconstruction.

Anatomic Single-Bundle Anterior Cruciate Ligament Reconstruction From the Anteromedial Portal: Evaluation of Transverse Femoral Fixation in a Cadaveric Model

PURPOSE The purpose of this study was to assess the risk of injury to the posterolateral structures of the knee when performing anterior cruciate ligament reconstruction from the anteromedial portal while fixing the graft with a femoral cross-pin system. METHODS The anterior cruciate ligament was reconstructed arthroscopically with hamstring graft in 10 fresh cadaveric knees. Femoral fixation was performed with a cross-pin system. This was originally developed for a transtibial drilling technique. A femoral tunnel measuring 30 mm in length was drilled through the anteromedial portal in each knee. The knee flexion angle was set at 110 degrees . Lateral dissection was then performed to measure the distances from the cross-pin system to the lateral collateral ligament, the popliteus tendon, the lateral gastrocnemius tendon, and the peroneal nerve. RESULTS The lateral collateral ligament was partially torn by the pin in 1 case. In 8 cases the distance to the lateral collateral ligament was shorter than 3 mm (range, 0 to 2.43 mm). In 7 specimens, the cross-pin system was within 4.5 mm of the popliteus tendon. The lateral gastrocnemius tendon was pierced by the cross-pin device in 2 cases. The minimal distance to the peroneal nerve was 23.89 mm. CONCLUSIONS Fixation of a hamstring graft with a cross-pin system initially developed for an upper femoral tunnel, following the aforementioned technique, presents the possibility of a high risk of injury to the lateral collateral ligament. The popliteus tendon and the lateral gastrocnemius tendon may also be injured. CLINICAL RELEVANCE The risk of injury to the lateral stabilizers of the knee suggests discarding the technique used in this study.

The magnetic resonance aspect of a polyurethane meniscal scaffold is worse in advanced cartilage defects without deterioration of clinical outcomes after a minimum two-year follow-up

BACKGROUND Meniscal scaffolding is thought to provide functional improvement and to prevent cartilage degeneration. Advanced chondral injuries might damage the scaffold structural properties. OBJECTIVE To evaluate the influence of different degrees of articular chondral injuries on the imaging aspect of a polyurethane meniscal scaffold (Actifit®). METHODS Fifty-four patients operated on with an Actifit® were studied. The status of the articular cartilage in the involved compartment was classified according to ICRS. The characteristics of the implant were evaluated in MRI with the Genovese score. Functional scores included WOMET, IKDC and Kujala scores. The Genovese score was correlated with the degree of chondral injury and functional results. RESULTS The mean follow-up was 39 months (range 25-63). Additional procedures were performed in 69.5%. There were 19 patients without chondral injuries and 14 with grade 1, 10 with grade 3 and eight with grade 4 chondral lesions. The morphology and size of the implant on MRI scanning were worse with a higher degree of chondral injury (p=0.023). WOMET, IKDC and Kujala improved from 36.2SD ±7.6, 32.3SD ±13.5 and 39.2SD ±8.1 to 75.8SD ±12.9 (p=0.02), 75.5SD ±15.4 (p=0.03) and 85.6SD ±13.4 (0.042), respectively. There was no relationship between the severity of chondral injury and functional scores. CONCLUSIONS Patients without chondral injuries showed a better MRI aspect of the polyurethane scaffold in terms of size and morphology. By optimizing biomechanics, in particular the implantation of a meniscal substitute, significant pain relief and functional improvement were observed after a minimum two-year follow-up. LEVEL OF EVIDENCE Therapeutic case series; level 4.

Magnetic resonance evaluation of TruFit® plugs for the treatment of osteochondral lesions of the knee shows the poor characteristics of the repair tissue

BACKGROUND Treatment of osteochondral lesions of the knee with synthetic scaffolds seems to offer a good surgical option preventing donor site morbidity. The TruFit® plug has frequently been shown to not properly incorporate into. OBJECTIVE To evaluate the relationship between MRI findings and functional scores of patients with osteochondral lesions of the knee treated with TruFit®. METHODS Patients were evaluated with MOCART score for magnetic resonance imaging assessment of the repair tissue. KOOS, SF-36 and VAS were used for clinical evaluation. Correlation between size of the treated chondral defect and functional scores was also analyzed. RESULTS Fifty-seven patients with median follow-up of 44.8 months (range 24-73) were included. KOOS, SF-36 and VAS improved from a mean 58.5, 53.9 and 8.5 points to a mean 87.4, 86.6 and 1.2 at last follow-up (p<0.001). Larger lesions showed less improvement in KOOS (p=0.04) and SF-36 (p=0.029). Median Tegner values were restored to preinjury situation (5, range 2-10). Mean MOCART score was 43.2 ± 16.1. Although the cartilage layer had good integration, it showed high heterogeneity and no filling of the subchondral bone layer. CONCLUSIONS TruFit® failed to restore the normal MRI aspect of the subchondral bone and lamina in most cases. The appearance of the chondral layer in MRI was partially re-established. This unfavourable MRI appearance did not adversely influence the patients outcome in the short time and they restored their previous level of activity. There was an inverse linear relationship between the size of the lesion and the functional scores. LEVEL OF EVIDENCE Therapeutic case series; level 4.

Effect of Femoral Tunnel Length on the Safety of Anterior Cruciate Ligament Graft Fixation Using Cross-Pin Technique: A Cadaveric Study

Background: A more oblique placement of the anterior cruciate ligament (ACL) graft has been related to better control of rotatory knee stability. Femoral fixation with a transverse system might injure its posterolateral structures. Hypothesis: A cross-pin system, originally developed for transtibial reconstruction of the ACL, can safely be used when creating a lower femoral tunnel through the anteromedial portal. However, a long femoral tunnel must be created to protect the posterolateral structures of the knee. Study Design: Controlled laboratory study. Methods: An ACL was arthroscopically reconstructed with a hamstring graft in 22 fresh cadaveric knees. The femoral tunnel was anatomically drilled in all cases. Knee flexion angle was set at 110°. Femoral fixation was performed with a cross-pin system. A 30-mm-long femoral tunnel was created in 11 knees (group A). In the remaining 11 knees, the femoral tunnel was drilled as long as each lateral condyle permitted (group B). For both groups, the relationships were compared between the cross-pin and the lateral collateral ligament (LCL), popliteus tendon, articular cartilage, and peroneal nerve. Results: In 5 cases of group A, the cross-pin was placed either through the LCL or between the LCL and popliteus tendon, whereas in group B it was always posterior to the LCL (P = .035). The cross-pin was closer to the articular cartilage in group A than in group B (7.14 mm versus 16.9 mm; P < .001). The minimal distance to the peroneal nerve in all specimens was 23.89 mm. Conclusion: Hamstring graft fixation with a cross-pin system from the anteromedial portal with a 30-mm femoral tunnel presents a higher risk of injury to the LCL. The femoral tunnel should be drilled as long as possible. Clinical Relevance: A long femoral tunnel is required for safe transverse femoral fixation in an anatomical ACL reconstruction.

Fibrosarcoma at the site of a metallic fixation of the tibia--a case report and literature review

treatment was closed in 5 cases with minimal displacement and surgical in the remaining 4 with a severe displacement. The mechanism of this juvenile fracture is well known; the keystone is the peculiar closure pattern of the distal tibial physis, which makes the lateral corner a weakened portion for a period of 18 months until complete closure occurs (Rang 1974). Injuries with the foot in external rotation and extension lead to avulsion of this physeal portion, due to excessive tension of the tibio-fibular ligament. In displacements exceeding 2 mm with a rotation of the fragment, open reduction and internal fixation have been suggested to obtain articular congruence (Stefanich and Lozman 1986, Mariani and Perrone 1998). Schlesinger and Wedge (1993) described percutaneous fixation of the displaced fragment. As to our patient, we were concerned about the quality of bone in the dislocated fragment, hence the possibility of obtaining good osteosynthesis with an anatomical reduction. The fragment was moderately porotic, but reduction and stable synthesis were possible. Another risk that had to be taken into account was avascular necrosis (AVN) of the fragment, which is theoretically increased by a delayed diagnosis and treatment. We found no sign of necrosis when we removed the screw and at the final follow-up, the boy had no symptoms.

Femoral Tunnel Drilling Angles for Posteromedial Corner Reconstructions of the Knee

PURPOSE To determine the best angle to drill the femoral tunnels of the superficial medial collateral ligament (sMCL) and posterior oblique ligament (POL) with concomitant posterior cruciate ligament (PCL) reconstruction to avoid either short tunnels or tunnel collisions. METHODS Eight cadaveric knees were studied. Double-bundle PCL femoral tunnels were arthroscopically drilled. Drilling of the sMCL and POL tunnels was performed in 4 different combinations of 0° and 30° axial (anteriorly directed) and coronal (proximally directed) angulations. Specimens were scanned with computed tomography to document the relations of the sMCL and POL tunnels to the intercondylar notch and PCL tunnels. A minimum tunnel length of 25 mm was required. RESULTS When the sMCL femoral tunnel was drilled at 0° axial and 30° coronal (proximally directed) angulations or 30° axial (anteriorly directed) and 0° coronal angulations, the risk of tunnel collision with the PCL tunnels increased in comparison with the remaining evaluated angulations (P < .001). No POL tunnels collided with either PCL tunnel bundle with the exception of tunnels drilled at 0° axial and 30° coronal (proximally directed) angulations, which did so in 3 of 8 cases (P < .001). The minimum required tunnel length was obtained in all the sMCL and POL tunnels (P < .001 and P = .02, respectively). However, some of those angled at 0° on the axial plane violated the intercondylar notch. CONCLUSIONS When one is performing posteromedial reconstructions with concomitant PCL procedures, the sMCL and POL femoral tunnels should be drilled anteriorly and proximally at both 30° axial and 30° coronal angulations. The POL femoral tunnel may also be angled 0° in the coronal plane. Tunnels at 0° axial angulations showed a shorter distance to the intercondylar notch and a higher risk of collision with the PCL tunnels. CLINICAL RELEVANCE Specific drilling angles are necessary to avoid short tunnels or collisions between the drilled tunnels when sMCL and POL femoral tunnels are placed with concomitant PCL reconstruction.