Xavier Pelfort

Factors affecting meniscal extrusion: correlation with MRI, clinical, and arthroscopic findings.

The existence of meniscal extrusion is well known in the natural history of the osteoarthritic knee. However, extruded menisci are also seen in non-pathologic knees. To ascertain the prevalence of meniscal extrusion in non-arthritic patients, the MRIs of 100 knees were prospectively studied. The data were correlated both with clinical and operative arthroscopic findings. The results showed 68.5% of the medial menisci to have some degree of extrusion, averaging at 28% of the meniscal size. While the lateral meniscus were extruded in 18.8% of cases at an average of 15% of the meniscal size. Furthermore, a relationship between the anterior insertion variant of the anterior medial meniscus and meniscal extrusion was found (P=0.001) in this series. The results suggest meniscal extrusion to be much more common in non-arthritic knees than previously estimated. The results also suggest that when the anterior horn of the medial meniscus inserts anteriorly in the tibial plateau, the meniscus tends to be extruded. It must be kept in mind that one of the limitations of this work is that the MRIs are taken in a non-weightbearing position.

Suture-Only Fixation Technique Leads to a Higher Degree of Extrusion Than Bony Fixation in Meniscal Allograft Transplantation

Background: Most of the published series of transplanted menisci have consistently shown some degree of allograft extrusion. The speculation is that this meniscal extrusion may be caused by the soft tissue technique used to fix the allograft. Hypothesis: The percentage of extruded meniscal graft would be higher if the allograft were only fixed with sutures rather than with associated bony fixation. Study Design: Cohort study; Level of evidence, 2. Methods: We performed a prospective series of 88 meniscal allograft transplantations. Thirty-three of the grafts were fixed with the suture-only technique (group A). The remaining 55 cases were performed with the bone plug method (group B). All patients were studied with magnetic resonance imaging (MRI) at a minimum 3 years’ follow-up to determine the degree of meniscal extrusion. The time between surgery and MRI evaluation was 40 months (range, 36-48 months) in both groups. Meniscal extrusion was measured on coronal MRI. The percentage of the meniscal body width that was extruded was calculated. The average percentage of extrusion for each group was compared. The Lysholm score was analyzed in relation to the fixation method and degree of meniscal extrusion. Tears of the allograft that required surgical intervention were also reported. Results: The average percentage of meniscal tissue extruded in group A was 36.3% ± 13.7% without differences between the medial (35.9% ± 18.1%) and lateral (38.3% ± 14.4%) compartments (P = .84). Group B had a mean 28.13% ± 12.2% of the meniscal body extruded without differences between the medial (25.8% ± 16.2%) and lateral (30.14% ± 13.5%) compartments. A higher percentage of extruded meniscal tissue was found in group A than in group B (P < .001). No association between the degree of meniscal extrusion and the functional score was observed (P = .4). Graft tears were observed in 21.4% of the cases in group A and in 7.3% of the cases in group B (P = .09). Conclusion: A meniscal allograft fixed with the suture-only technique showed a significantly higher degree of extruded meniscal body than that fixed with the bony fixation method, with no influence on the functional outcome. There was also a considerably higher rate of graft tears observed in those menisci fixed only with sutures, although this difference was not statistically significant with the numbers available.

Meniscal Allograft Transplantation Without Bone Blocks: A 5- to 8-Year Follow-Up of 33 Patients

PURPOSE The purpose of this study was to evaluate the functional and radiographic results on a midterm basis, as well as complications, in an initial series of meniscal allograft transplantations performed with suture fixation without any bone block. METHODS A series of 33 meniscal allograft transplantations were performed at our institution from January 2001 to October 2003. Inclusion criteria were patients with compartmental joint line pain due to a previous meniscectomy. There were 24 men and 9 women with a mean age of 38.8 years (range, 21 to 54 years). The functional outcomes were evaluated by use of Lysholm and Tegner scores at a mean and minimum follow-up of 6.5 years and 5 years, respectively. A visual analog scale for pain was also used. Radiographic assessment included joint space narrowing on the Rosenberg view and magnetic resonance imaging evaluation. RESULTS The Lysholm and Tegner scores significantly improved from 65.4 to 88.6 (P < .001) and from 3.1 to 5.5 (P < .001), respectively, after surgery. The visual analog scale score significantly dropped from 6.4 to 1.5 (P < .001). The radiographic evaluation did not show any joint space narrowing (P = .38). Meniscal extrusion was a constant finding, averaging 36.3% of total meniscal size. According to the Van Arkel criteria, the survival rate was 87.8% at 6.5 years. The rate of complications was 33%. CONCLUSIONS This study suggests that this procedure provides significant pain relief and functional improvement in selected symptomatic individuals on a midterm basis. However, there was a high rate of complications (33%) and revision surgery. LEVEL OF EVIDENCE Level IV, therapeutic case series.

The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees.

BACKGROUND The use of antibiotic-loaded cement is believed to prevent infection in primary total knee arthroplasty, but there is a lack of randomized studies to support this concept. The aim of this study was to evaluate the use of an antibiotic-loaded cement to reduce the infection rate in primary total knee arthroplasty. METHODS This is a prospective randomized study with 2948 cemented total knee arthroplasties, in which bone cement without antibiotic was used in 1465 knees (the control group) and a bone cement loaded with erythromycin and colistin was used in 1483 knees (the study group). All patients received the same systemic prophylactic antibiotics. The patients were followed for a minimum of twelve months. The rate of infection was analyzed according to the criteria of the Centers for Disease Control and Prevention. RESULTS The rate of deep infection (1.4% in the control group and 1.35% in the study group; p = 0.96) and the rate of superficial infection (1.2% and 1.8%, respectively; p = 0.53) were similar in both groups. The factors related to a higher rate of deep infection in a multivariate analysis were male sex and an operating time of >125 minutes. CONCLUSIONS The use of erythromycin and colistin-loaded bone cement in total knee arthroplasty did not lead to a decrease in the rate of infection when systemic prophylactic antibiotics were used, a finding that suggests that the use of antibiotic-loaded bone cement would not be indicated in the general population. Further research is needed to assess whether its use is recommended for patients with a higher risk of infection.

Influence of Depression on Total Knee Arthroplasty Outcomes

It is not clear whether indicating TKA-surgery is advisable in depressed patients. A prospective cohort of 716 patients undergoing TKA was designed. SF36, KSS, WOMAC and VAS plus 2 satisfaction questions were evaluated. There were 2 groups: 200 patients were depressed and 516 were not. Preoperative/postoperative results show better scores for non-depressed patients on almost every sub-scale. Nevertheless, net change results (improvement) were quite similar: 65.74 improvement in depressed-KSS and 74.58 in non-depressed (P=0.049); 8.93 net change in depressed-Physical Composite Score and 11.84 in non-depressed (P=0.003); 2.38 in depressed-Mental Composite Score and -0.61 in non-depressed (P=0.024). Depressed patients obtained great improvement from preoperative at one-year follow-up and even greater than non-depressed patients in some domains. Moreover, satisfaction was similar. Therefore, TKA can be recommended to depressed patients.

Effectiveness of a Footprint Guide to Establish an Anatomic Femoral Tunnel in Anterior Cruciate Ligament Reconstruction: Computed Tomography Evaluation in a Cadaveric Model

PURPOSE To compare drilling the femoral tunnel with an offset aimer and BullsEye guide (ConMed Linvatec, Largo, FL) to perform an anatomic single-bundle reconstruction of the anterior cruciate ligament (ACL) through the anteromedial portal. METHODS Seven matched pairs of cadaveric knees were studied. The intent was to drill the femoral tunnel anatomically in all cases. In group A the femoral tunnel was drilled arthroscopically with an offset aimer. In group B the femoral tunnel was drilled arthroscopically with the BullsEye guide. Two tunnels were drilled through the same entry point in each knee. One was done at 110° of knee flexion and the other at 130°. They were scanned by computed tomography and reconstructed 3-dimensionally. Volume-rendering software was used to document relations of the drilled tunnel to the bony anatomy and tunnel length. RESULTS In group B the femoral tunnel was placed at the center of the femoral insertion site. The center of the tunnel was 9.4 mm from the high cartilage margin and 8.6 mm from the low cartilage margin. In group A the tunnels were placed deeper (5.4 mm and 12.6 mm, respectively) (P = .018). There were no differences in tunnel length for either knee flexion degree. Three of the tunnels drilled at 110° in group A compromised the posterior tunnel wall and measured less than 25 mm in length. CONCLUSIONS Accurate placement in the center of the femoral footprint of the ACL is better accomplished with the BullsEye guide rather than 5-mm offset aimers. Five-millimeter offset aimers might cause posterior tunnel blowout and present the risk of obtaining short tunnels when performing oblique femoral tunnel placement through the anteromedial portal at 110° of knee flexion. CLINICAL RELEVANCE The BullsEye guide might be better than standard offset aimers in the performance of anatomic single-bundle ACL reconstruction.

Anatomic Single-Bundle Anterior Cruciate Ligament Reconstruction From the Anteromedial Portal: Evaluation of Transverse Femoral Fixation in a Cadaveric Model

PURPOSE The purpose of this study was to assess the risk of injury to the posterolateral structures of the knee when performing anterior cruciate ligament reconstruction from the anteromedial portal while fixing the graft with a femoral cross-pin system. METHODS The anterior cruciate ligament was reconstructed arthroscopically with hamstring graft in 10 fresh cadaveric knees. Femoral fixation was performed with a cross-pin system. This was originally developed for a transtibial drilling technique. A femoral tunnel measuring 30 mm in length was drilled through the anteromedial portal in each knee. The knee flexion angle was set at 110 degrees . Lateral dissection was then performed to measure the distances from the cross-pin system to the lateral collateral ligament, the popliteus tendon, the lateral gastrocnemius tendon, and the peroneal nerve. RESULTS The lateral collateral ligament was partially torn by the pin in 1 case. In 8 cases the distance to the lateral collateral ligament was shorter than 3 mm (range, 0 to 2.43 mm). In 7 specimens, the cross-pin system was within 4.5 mm of the popliteus tendon. The lateral gastrocnemius tendon was pierced by the cross-pin device in 2 cases. The minimal distance to the peroneal nerve was 23.89 mm. CONCLUSIONS Fixation of a hamstring graft with a cross-pin system initially developed for an upper femoral tunnel, following the aforementioned technique, presents the possibility of a high risk of injury to the lateral collateral ligament. The popliteus tendon and the lateral gastrocnemius tendon may also be injured. CLINICAL RELEVANCE The risk of injury to the lateral stabilizers of the knee suggests discarding the technique used in this study.

Arthroscopic Treatment of Hip Chondral Defects With Bone Marrow Stimulation and BST-CarGel

Microfracture, the current standard of care for the treatment of non-degenerative chondral lesions in the hip joint, is limited by the poor quality of the filling fibrocartilaginous tissue. BST-CarGel (Piramal Life Sciences, Laval, Quebec, Canada) is a chitosan-based biopolymer that, when mixed with fresh, autologous whole blood and placed over the previously microfractured area, stabilizes the blood clot and enhances marrow-triggered wound-healing repair processes. BST-CarGel has been previously applied in the knee, with statistically significant greater lesion filling and superior repair tissue quality compared with microfracture treatment alone. In this report we describe the application of BST-CarGel for the arthroscopic treatment of hip chondral lesions. Our preliminary data suggest that our BST-CarGel procedure provides high-quality repair tissue and therefore may be considered a safe, cost-efficient therapeutic choice for the treatment of hip chondral defects.

Correlation Study Between KSS, WOMAC and SF-36 Scores in Patients Undergoing Total Knee Arthroplasty in a Spanish Speaking Population

The aim of this study was to determine whether it is necessary to use the KSS, WOMAC and SF-36 scales in a Spanish speaking population. These 3 questionnaires were administered to 1000 consecutive patients in the TKA preoperative period. Pearsons correlation coefficient and coefficient of determination were obtained. 196 patients were excluded. A poor correlation was obtained comparing the different items of the different scores with each other. Only in 3 out of different comparisons performed was a Pearsons correlation r>0.5 obtained. The worst results were obtained comparing the two knee specific tests (SF-36 vs WOMAC) and the best ones comparing SF-36 and WOMAC scores. Based on these results, the use of the three tests in the TKA preoperative period is recommended in a Spanish speaking population.

Cervicocephalic medial screw migration after intertrochanteric fracture fixation, OTA/AO 31-A2, using intramedullary nail Gamma3: report of 2 cases and literature review.

Summary: Cervicocephalic screw medialization is a rare complication after intertrochanteric fracture synthesis with a Gamma3-type intramedullary nail. Only 6 cases of intrapelvic penetration by Gamma3 lag screw have been described. We now describe 2 additional cases and a review of the literature.