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Dive into the research topics where Juergen Alves is active.

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Featured researches published by Juergen Alves.


Biochemistry | 1992

A site-directed mutagenesis study to identify amino acid residues involved in the catalytic function of the restriction endonuclease EcoRV.

Ursel Selent; Thomas Rueter; Eleonore Koehler; Michaela Liedtke; Vera Thielking; Juergen Alves; Thomas Oelgeschlaeger; Heiner Wolfes; Frens Peters; Alfred Pingoud


Proceedings of the National Academy of Sciences of the United States of America | 1993

Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes

Albert Jeltsch; Juergen Alves; Heiner Wolfes; Günter Maass; Alfred Pingoud


Biochemistry | 1994

PAUSING OF THE RESTRICTION ENDONUCLEASE ECORI DURING LINEAR DIFFUSION ON DNA

Albert Jeltsch; Juergen Alves; Heiner Wolfes; Guenter Maass; Alfred Pingoud


Analytical Biochemistry | 1993

A Fast and Accurate Enzyme-Linked Immunosorbent Assay for the Determination of the DNA Cleavage Activity of Restriction Endonucleases

Albert Jeltsch; A. Fritz; Juergen Alves; Heiner Wolfes; Alfred Pingoud


Biochemistry | 1990

Accuracy of the EcoRV restriction endonuclease: binding and cleavage studies with oligodeoxynucleotide substrates containing degenerate recognition sequences.

Juergen Alves; Ursel Selent; Heiner Wolfes


Biochemistry | 1984

Effect of polyamines and basic proteins on cleavage of DNA by restriction endonucleases.

Alfred Pingoud; Claus Urbanke; Juergen Alves; Hans Juergen Ehbrecht; Marc Zabeau; Claudio O. Gualerzi


Biochemistry | 1989

Genetic engineering of EcoRI mutants with altered amino acid residues in the DNA binding site: physicochemical investigations give evidence for an altered monomer/dimer equilibrium for the Gln144Lys145 and Gln144Lys145Lys200 mutants.

Robert Geiger; Rüter T; Juergen Alves; Anja Fliess; Heiner Wolfes; Pingoud; Claus Urbanke; Guenter Maass; Alfred Pingoud; Düsterhöft A


Biochemistry | 1989

Fluorescence stopped-flow kinetics of the cleavage of synthetic oligodeoxynucleotides by the EcoRI restriction endonuclease.

Juergen Alves; Claus Urbanke; Anja Fliess; Guenter Maass; Alfred Pingoud


Biochemistry | 1997

Sequence context influencing cleavage activity of the K130E mutant of the restriction endonuclease EcoRI identified by a site selection assay.

Windolph S; Fritz A; Oelgeschläger T; Heiner Wolfes; Juergen Alves


Biochemistry | 1988

Spectroscopic and hydrodynamic studies reveal structural differences in normal and transforming H-ras gene products

Alfred Pingoud; Mathias Wehrmann; Uwe Pieper; Frank Ulrich Gast; Claus Urbanke; Juergen Alves; Juergen Feuerstein; Alfred Wittinghofer

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