Junji Oda

Vascular occlusion and cartilage disorders in osteonecrosis of the femoral head in rats

Summary. The aim of our study was to clarify the role of lateral epiphyseal vessels in the development of femoral head osteonecrosis in rats. We did this by performing histological and immunological studies on rats at the age that they are most prone to spontaneous osteonecrosis. We observed that obstruction of the lateral epiphyseal vessels occurred at the site of cartilage penetration. This obstruction preceded the development of osteonecrosis in adjacent areas of the femoral head. We propose that a similar mechanism may be responsible, in part, for the development of Perthes’ disease in man.

Osteonecrosis of the femoral head in spontaneously hypertensive rats : relation to ossific nuclei during growth

We observed the distribution of the ossific nuclei and the occurrence of osteonecrosis in the femoral capital epiphysis of spontaneously hypertensive rats. In 270 femoral heads, the ossific nuclei were seen in the following sites of the epiphysis: Type 1, the lateral portion in 150 femoral heads; Type 2, the central portion in 5 heads; Type 3, both lateral and central portions in 12 heads; and Type 4, throughout the epiphysis in 62 heads. The number of femoral heads with osteonecrosis in Types 1-4 was 61, 0, 5, and 17, respectively.

Clinical Results of Surgical Treatment for Rotator Cuff Tear in Tsushima

We treated rotator cuff tears surgically by the McLaughlin method on 14 cases from 1994 to 1997. They were followed up for an average of 26 months (range, 6 to 52). There were 11 were men and 5 were women. The average age of the patients was 58.1 years (range, 48 to 68). The clinical results were evaluated using the JOA score system and questionnaires on the patients satisfaction and problems and self score system (10 point method). The average JOA score was 96.1 points. The average 10 points score was 8.9 points.

Osteonecrossi of the Femoral Head in Spontaneously Hypertensive Rats. Endochondral ossification disturbance laterally in the epiphyseal growth plate of the femoral head.:Endochondral ossification disturbance laterally in the epiphyseal growth plate of the femoral head

Using a digitizer system, we histologically measured bone volume beneath the growth plate in the proximal femoral metaphysis of spontaneously hypertensive rats (SHRs) aged from 5 to 9 weeks. Wister Kyoto rats (WKRs) were used as controls. Histomorphometry was conducted in the lateral and medial portions of the metaphysis.In SHRs, bone volume in the lateral portions was less than that in the medial portions at 5, 6, 8 and 9 weeks of age.In comparison, in WKRs, there was no difference in bone volume between the two portions at the different ages.These results suggest that endochondral ossification in the lateral part of the plate is disturbed unevenly in early ages, that is before osteonecrosis occurred in SHRs.