Junmin Chen

Stereoselective synthesis of 1,3-enynyltellurides via palladium catalysed cross-coupling reaction of (E)-α-iodovinyltellurides

(E)-α-Iodovinyltellurides undergo a direct coupling reaction with terminal alkynes in the presence of [Pd(PPh3)4] and CuI catalysts in pyrrolidine at room temperature to give 1,3-enynyltellurides in good yields.

Stereoselective synthesis of (Z)-α-arylsulfenylvinyl tellurides via hydrozirconation of alkynyltellurides

Hydrozirconation of alkynyltellurides 1 in THF at room temperature gave (Z)-α- tellurenylvinylzirconium complexes 2, which were reacted with arylsulfenyl chlorides 3 to afford stereoselectively (Z)-α-arylsulfenylvinyl tellurides 4 in good yields.

Novel stereoselective synthesis of (E)-cinnamonitriles via Heck arylation of acrylonitrile catalysed by a silica-supported bidentate arsine palladium(0) complex

(E)-Cinnamonitriles have been synthesised stereoselectively in high yields via Heck arylation of acrylonitrile with aryl iodides catalysed by a silica-supported bidentate arsine palladium(0) complex. This polymeric palladium(0) complex can be recovered and reused without noticeable loss of activity.

Primary sulfonamide as a coupling partner: Copper(I)-catalyzed regioselective cross-coupling of 2-nitro benzenesulfonamides with thiol through the cleavage of Ar–SO2NH2 bonds

ABSTRACT In this article, we have presented a novel and efficient method for the direct synthesis of unsymmetrical sulfides through the copper(I)-catalyzed cross-coupling of 2-nitro benzenesulfonamides with thiols in the presence of catalytic amount of CuI in DMF as solvent at 100u2009°C. In addition, the products were obtained in high to excellent yields. More importantly, the novel system showed the primary 2-nitro benzenesulfonamides as a new coupling partner and regioselectively promoted C–S bond-forming transformations through the cleavage of Ar–SO2NH2 bonds. GRAPHICAL ABSTRACT

Metal-free sequential dual oxidative amination of C(sp3)–H bonds: A direct approach to benzothiadiazine 1,1-dioxide derivatives

ABSTRACT An efficient and metal-free Di-tert-butyl peroxide (DTBP)-promoted dual oxidative amination annulation of 2-amino arylsulfonamide with methylarene has been developed. This protocol provides straightforward access to benzothiadiazine 1,1-dioxide derivatives without using prefunctionalized substrates in good to excellent yields with good functional group tolerance. GRAPHICAL ABSTRACT

Cu(II)-catalyzed decarboxylation/elimination of N-arylsulfonyl amino acids to primary aryl sulfonamides

ABSTRACT A novel protocol for CuO-catalyzed decarboxylation/elimination of N-arylsulfonyl amino acids was developed. It is the first example of using an accessible amino acid as an ammonia synthetic equivalent for the synthesis of primary aryl sulfonamides via oxidative decarboxylation/elimination reactions. The present protocol shows excellent functional group tolerance and provides an efficient method for the synthesis of primary aryl sulfonamides in excellent yields. GRAPHICAL ABSTRACT

Novel stereoselective synthesis of 1,3-dien-2-yl esters by a palladium-catalysed cross-coupling reaction of (E)-α-iodo-α,β-unsaturated esters

(E)-α-Stannyl-α,β-unsaturated esters underwent an iododestannylation reaction to afford (E)-α-iodo-α,β-unsaturated esters, which reacted with (E)-alkenylzirconium(IV) complexes produced in situ by hydrozirconation of terminal alkynes in the presence of Pd(PPh3)4 to afford stereoselectively a variety of 1,3-dien-2-yl esters in good yields.

A facile stereoselective synthesis of 1,3-dienyltellurides via palladium catalysed cross-coupling reactions

Hydrozirconation of terminal alkynes 1 gives (E)-alkenylzirconium complexes 3, which cross-couple with (E)-α-iodovinyltellurides 4 in the presence of [Pd(PPh3)4] catalyst to afford stereoselectively 1,3-dienyltellurides 5 in good yields.