K. A. Potekhin

Synthesis of chiral 1,3-dihydroisobenzofurans (phthalans) containing functional substituents in the 1-position

Chiral 3-methyl-1,3-dihydroisobenzofurans (phthalans) having a carbonyl or α-hydroxybenzyl group in position 1 were synthesized by cyclization of the corresponding trimethyl[(S)-1-phenylethyl]ammonium iodides. The configuration of the chiral centers in the products was determined by X-ray analysis.

New chiral ligands: 1,4-diols prepared from (S)-1-phenylethanol

The stereochemistry of condensation of dilithiated 1-phenylethanol with various carbonyl compounds was investigated. In most cases the reaction proceeds nonstreoselectively, and only in the condensation with PhCOBu-t and 2,4-(MeO)2C6H3COPh only one of the diastereomeric diols prevailed. It was shown by XRD analysis that in the prevailing diastereomeric diol the newly formed chiral carbinol center possessed the same configuration as the initial alcohol. The synthesized diols form homochiral dimers in the crystal lattice.

Molecular and crystal structures of (S,S)-[o-(α-dimethylaminoethyl)phenyl]phenylarylcarbinols

AbstractThe crystal structures of (S,S)-o-(α-dimethylaminoethyl)phenyl]phenyl-2,4-dimethylphenyl-carbinol (I) and (S,S)-o-(α-dimethylaminoethyl)phenyl]phenyl-2,4,5-trimethylphenylcarbinol (II) are determined by X-ray diffraction. The molecular and crystal structures of I and II are similar. The crystal structures of I and II are compared based on the analysis of the geometric characteristics of the Vorono

Modeling and X-ray diffraction investigation of the crystal structure of 1,1-diphenyl-3-methyl-6,7-dimethoxy-1,3-dihydroisobenzofuran

\overset{\lower0.5em\hbox{

Mathematical simulation and X-ray diffraction investigation of the crystal structure of 1-phenyl-1-tert-butyl-3-methyl-1,3-dihydroisobenzofuran

\smash{\scriptscriptstyle\smile}

Mathematical simulation and X-ray diffraction investigation of the crystal structure of (R)-[(R)-o-(1-N,N-dimethylaminoethyl)phenyl]-2,5-dimethoxyphenyl(phenyl)methanol

}}{l}

THE CRYSTAL AND MOLECULAR-STRUCTURE OF 3,7-DIMETHYL-1,5-DIPHENYLBISPIDONE-9 - COPPER(II) CHLORIDE 1-1 COMPLEX

2-Dirichlet packing polyhedra. The circular dichroism spectra of amino alcohols I and II revealed a strong positive Cotton effect in the region of 230 nm, which correlates with the S-configuration of the chiral carbinol center.

Crystal structure of synthetic ortho-3-borate Al5(BO3)O6

The condensation of lithiated (S)-N,N-dimethyl-1-phenylethylamine with o-methoxybenzophenones occurs in a nonstereoselective fashion due to possible coordination of lithium not only at the carbonyl group but also at the oxygen atom of the ortho-methoxy group.