K. Saiki

Diagnosis of the level and severity of cord lesion in cervical spondylotic myelopathy. Spinal evoked potentials.

Experimental and clinical studies were performed to measure the segmental spinal evoked potential (SEP) of the cervical cord after stimulation of the median nerve, to determine the location, severity, and outcome of cord lesion in patients who had cervical spondylotic myelopathy. The SEP in control subjects consisted of two waves, the primary reactive R-wave and the secondary reactive N-wave. The R-wave related to both the dorsal root potential and the funiculus posterior potential; the N-wave related to the post-synaptic potential in the spinal cord. In the early stages of cervical spondylotic myelopathy, the N-wave weakens or disappears at the level of lesion. Then, as damage progresses, the R-wave also weakens or disappears.

Evaluation of cervical cord function in cervical spondylotic myelopathy and/or radiculopathy using both segmental conductive spinal-evoked potentials (SEP)

To evaluate the function of the cervical cord and to diagnose the level and severity of cervical cord lesions in myelopathy, both segmental and conductive spinal evoked potentials (SEP) were measured in 73 patients with cervical spondylotic myelopathy and/or radiculopathy. In normal subjects, segmental SEPs consisted of two waves (R and N waves). Ascending conductive SEPs also consisted of two waves (first and second waves). The function of the cervical cord, including roots, grey matter, and white matter, can be measured by the combined method using both segmental and conductive SEPs, and this allows differentiation among radiculopathy and various types of myelopathy.