Karel De Loof
Ghent University
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Publication
Featured researches published by Karel De Loof.
Combinatorial Chemistry & High Throughput Screening | 2008
Karel De Loof; Bernard De Baets; Hans De Meyer; Rainer Brüggemann
When ranking objects (like chemicals, geographical sites, river sections, etc.) by multicriteria analysis, it is in most cases controversial and difficult to find a common scale among the criteria of concern. Therefore, ideally, one should not resort to such artificial additional constraints. The theory of partially ordered sets (or posets for short) provides a solid formal framework for the ranking of objects without assigning a common scale and/or weights to the criteria, and therefore constitutes a valuable alternative to traditional approaches. In this paper, we aim to give a comprehensive literature review on the topic. First we formalize the problem of ranking objects according to some predefined criteria. In this theoretical framework, we focus on several algorithms and illustrate them on a toy example. To conclude, a more realistic real-world application shows the power of some of the algorithms considered in this paper.
Systematic and Applied Microbiology | 2013
Wim De Smet; Karel De Loof; Paul De Vos; Peter Dawyndt; Bernard De Baets
StrainInfo has augmented its type strain and species/subspecies passports with a recommendation for a high-quality 16S rRNA gene sequence available from the public sequence databases. These recommendations are generated by an automated pipeline that collects all candidate 16S rRNA gene sequences for a prokaryotic type strain, filters out low-quality sequences and retains a high-quality sequence from the remaining pool. Due to thorough automation, recommendations can be renewed daily using the latest updates of the public sequence databases and the latest species descriptions. We discuss the quality criteria constructed to filter and rank available 16S rRNA gene sequences, and show how a partially ordered set (poset) ranking algorithm can be applied to solve the multi-criteria ranking problem of selecting the best candidate sequence. The proof of concept of the recommender system is validated by comparing the results of automated selection with an expert selection made in the All-Species Living Tree Project. Based on these validation results, the pipeline may reliably be applied for non-type strains and developed further for the automated selection of housekeeping genes.
international conference information processing | 2012
Karel De Loof; Bernard De Baets; Hans De Meyer
It is known that the winning probability relation of a dice model, which amounts to the pairwise comparison of a set of independent random variables that are uniformly distributed on finite integer multisets, is dice transitive. The condition of dice transitivity, also called the 3-cycle condition, is, however, not sufficient for an arbitrary rational-valued reciprocal relation to be the winning probability relation of a dice model. An additional necessary condition, called the 4-cycle condition, is introduced in this contribution. Moreover, we reveal a remarkable relationship between the 3-cycle condition and the number of so-called product triplets of a reciprocal relation. Finally, we experimentally count product triplets for several families of winning probability relations.
soft methods in probability and statistics | 2008
Bernard De Baets; Hans De Meyer; Karel De Loof
In this paper, the transitivity properties of reciprocal relations, also called probabilistic relations, are investigated within the framework of cycle-transitivity. Interesting types of transitivity are highlighted and shown to be realizable in applications. For example, given a collection of random variables (X k )k ∈ I, pairwisely coupled by means of a same copula C ∈ {T M , T P , T L }, the transitivity of the reciprocal relation Q defined by \(Q (X_i,X_j) = {\rm Prob}\{X_i X_j\} + 1/2 {\rm\ Prob}\{X_i=X_j\}\) can be characterized within the cycle- transitivity framework. Similarly, given a poset (P, ≤ ) with P = {x 1, ..., x n }, the transitivity of the mutual rank probability relation Q P , where Q P (X i ,X j ) denotes the probability that x i precedes x j in a random linear extension of P, is characterized as a type of cycle-transitivity for which no realization had been found so far.
Fundamenta Informaticae | 2006
Karel De Loof; Hans De Meyer; Bernard De Baets
Match-communications in Mathematical and in Computer Chemistry | 2011
Karel De Loof; Bernard De Baets; Hans De Meyer
8th Partial Order Workshop: Workshop on Hasse diagrams, Partial orders and Applications | 2008
Karel De Loof; Bernard De Baets; Hans De Meyer
Match-communications in Mathematical and in Computer Chemistry | 2012
Karel De Loof; Michaël Rademaker; Rainer Brüggemann; Hans De Meyer; Guillermo Restrepo; Bernard De Baets
soft methods in probability and statistics | 2006
Karel De Loof; Hans De Meyer; Bernard De Baets
Software - Practice and Experience | 2009
Gunnar Brinkmann; Jan Degraer; Karel De Loof