Kayhan Ozkan
Ondokuz Mayıs University
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Publication
Featured researches published by Kayhan Ozkan.
American Journal of Emergency Medicine | 2003
Cafer Polat; Adem Dervisoglu; Hakan Güven; Ekrem Kaya; Zafer Malazgirt; Murat Danaci; Kayhan Ozkan
Intramural hematoma of the intestine is a rare complication of anticoagulant therapy. We evaluated 7 nontrauma patients with intramural hematoma of the intestine diagnosed at our institution between May 1998 and June 2001. All of the patients were receiving long-term anticoagulant therapy for previous diseases. All 7 patients had abdominal pain, 6 had additional symptoms of nausea and vomiting, and 4 had melanotic stools at admission. Six of the patients had abnormal coagulation parameters. Both abdominal ultrasonography (US) and computerized tomography (CT) showed the exact pathology in all patients. Five of the 7 patients were treated, nonoperatively, and the other patients underwent surgery. All of the patients were followed with abdominal US and CT (mean 12 = months), with complete resolution of their intramural hematomas. Abdominal US and CT evaluation performed together will help the accuracy of diagnosis of intramural hematoma, but nonoperative therapy is the treatment of choice, with surgery indicated if generalized peritonitis or intestinal obstruction develops.
Journal of Trauma-injury Infection and Critical Care | 2002
Hakan Güven; Ramazan Amanvermez; Zafer Malazgirt; Ekrem Kaya; Zahide Doganay; Cemil Çelik; Kayhan Ozkan
BACKGROUND The purpose of this study was to investigate the effects of temperature on oxidative stress in brain stem tissue induced by hemorrhagic shock. We researched the hemorrhagic oxidative stress at various core temperatures using reduced glutathione (GSH) levels and thiobarbituric acid-reactive substances (TBARS) as markers of lipid peroxidation in brain stem homogenate. METHODS Forty rats were divided into four groups, of which one constituted the nonbleeding normothermia control group. In all of the three study groups, 40% of estimated blood volume was removed while they were being held at normothermia, mild hypothermia (32 degrees C), or moderate hypothermia (28 degrees C). Parameters including mean arterial pressure, rectal temperature, and heart and breathing rates were monitored and recorded during the procedures. After an hour at shock state, tissue samples were removed by craniectomy. RESULTS The tissue levels of TBARS increased significantly in normothermic and mild hypothermic hemorrhagic shock groups (10.74 nmol/g and 8.26 nmol/g) as compared with the control group (3.50 nmol/g) (p < 0.001). However, the tissue TBARS level in the moderate hypothermia group was only minimally increased (4.53 nmol/g). GSH showed a slight decrease in normothermic and mild hypothermic bleeding rats, and were unchanged in the moderate hypothermic rats. CONCLUSION Moderate systemic hypothermia (28 degrees C) appears to protect brain stem tissue from oxidative stress during severe hemorrhagic shock in rats, as indicated by insignificant change in tissue TBARS and GSH concentrations. These results suggest antioxidant protective effects of moderate systemic hypothermia in metabolically active brain stem tissue during hemorrhagic shock. Similar effects in humans remain to be studied.
World Journal of Gastroenterology | 2005
Kenan Erzurumlu; Zafer Malazgirt; Ahmet Bektas; Adem Dervisoglu; Cafer Polat; Gokhan Senyurek; Ibrahim Yetim; Kayhan Ozkan
American Journal of Surgery | 2005
Cafer Polat; Adem Dervisoglu; Gokhan Senyurek; Mehmet Bilgin; Kenan Erzurumlu; Kayhan Ozkan
World Journal of Gastroenterology | 2005
Ekrem Kaya; Adem Dervisoglu; Cafer Eroglu; Cafer Polat; Mustafa Sunbul; Kayhan Ozkan
Hernia | 2000
Zafer Malazgirt; Kayhan Ozkan; Adem Dervisoglu; E. Kaya
Parasite | 2001
Cemil Çelik; Ramazan Amanvermez; Kayhan Ozkan
Archive | 2005
Cafer Polat; Adem Dervisoglu; Gokhan Senyurek; Mehmet Bilgin; Kenan Erzurumlu; Kayhan Ozkan
Turkish journal of trauma & emergency surgery | 2000
Ekrem Kaya; Osman Selçuk; Adem Dervisoglu; Zafer Malazgirt; Necati Özen; Kayhan Ozkan
Archive | 2000
Ekrem Kaya; Adem Dervisoglu; M Fikret Gürsel; Zafer Malazgirt; Kayhan Ozkan