Kazutoshi Miyake
Eisai
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Publication
Featured researches published by Kazutoshi Miyake.
Bioorganic & Medicinal Chemistry Letters | 1994
Kazutoshi Miyake; Masayuki Matsukura; Naoki Yoneda; Osamu Hiroshima; Nobuyuki Mori; Hiroki Ishihara; Takashi Musha; Toshiyuki Matsuoka; Tadao Shoji; Norio Minami; Sachiyuki Hamano; Isao Saito
Abstract A phenolic benzofuran derivative 1 was identified as an angiotensin II receptor antagonist by random screening. Structural modifications led to a novel series of N-(4-hydroxyphenylmethyl)benzimidazoles and imidazo[4,5-b]pyridines, some of which inhibited angiotensin II-induced contractions in rabbit aortic strips with pA2 values of nearly 9. The related biphenylmethyl derivative E4177 showed potent and long-lasting activity in vivo.
Archive | 1994
Hitoshi Oinuma; Shinji Suda; Naoki Yoneda; Makoto Kotake; Kenji Hayashi; Kazutoshi Miyake; Nobuyuki Mori; Mamoru Saito; Toshiyuki Matsuoka; Masayuki Namiki; Takeshi Sudo; Shigeru Souda
Archive | 1990
Kazutoshi Miyake; Masayuki Matsukura; Naoki Yoneda; Osamu Hiroshima; Nobuyuki Mori; Hiroki Ishihara; Takashi Musha; Toshiyuki Matsuoka; Sachiyuki Hamano; Norio Minami
Official Gazette of the United States Patent and Trademark Office Patents | 1995
Nobuhisa Watanabe; Yasuhiro Kabasawa; Yasutaka Takase; Fumihiro Ozaki; Keiji Ishibashi; Kazuki Miyazaki; Masayuki Matsukura; Shigeru Souda; Kazutoshi Miyake; Hiroki Ishihara; Kohtaro Kodama; Hideyuki Adachi
Synthesis | 1996
Shigeto Negi; Masayuki Matsukura; Masanori Mizuno; Kazutoshi Miyake; Norio Minami
Archive | 1987
Hitoshi Oinuma; Motosuke Yamanaka; Kazutoshi Miyake; Tomonori Hoshiko; Norio Minami; Tadao Shoji; Yoshiharu Daiku; Kohei Sawada; Kenichi Nomoto
Archive | 1987
Hitoshi Oinuma; Motosuke Yamanaka; Kazutoshi Miyake; Tomonori Hoshiko; Norio Minami; Tadao Shoji; Yoshiharu Daiku; Kohei Sawada; Kenichi Nomoto
Archive | 1982
Noriyasu Hirose; Shigeru Souda; Kazutoshi Miyake; Shizuo Kuriyama; Kazuyasu Usuki; Yasuhiro Akiyama; Naoko Sakabe; Hidetoshi Kawashima
Archive | 1990
Kazutoshi Miyake; Masayuki Matsukura; Naoki Yoneda; Osamu Hiroshima; Nobuyuki Mori; Hiroki Ishihara; Takashi Musha; Toshiyuki Matsuoka; Sachiyuki Hamano; Norio Minami
Journal of Medicinal Chemistry | 1990
Hitoshi Oinuma; Kazutoshi Miyake; Motosuke Yamanaka; Kenichi Nomoto; Hiroshi Katoh; Kohei Sawada; Mitsumasa Shino; Sachiyuki Hamano
