Norio Minami
Eisai
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Publication
Featured researches published by Norio Minami.
Bioorganic & Medicinal Chemistry Letters | 1994
Kazutoshi Miyake; Masayuki Matsukura; Naoki Yoneda; Osamu Hiroshima; Nobuyuki Mori; Hiroki Ishihara; Takashi Musha; Toshiyuki Matsuoka; Tadao Shoji; Norio Minami; Sachiyuki Hamano; Isao Saito
Abstract A phenolic benzofuran derivative 1 was identified as an angiotensin II receptor antagonist by random screening. Structural modifications led to a novel series of N-(4-hydroxyphenylmethyl)benzimidazoles and imidazo[4,5-b]pyridines, some of which inhibited angiotensin II-induced contractions in rabbit aortic strips with pA2 values of nearly 9. The related biphenylmethyl derivative E4177 showed potent and long-lasting activity in vivo.
Archive | 1990
Kazutoshi Miyake; Masayuki Matsukura; Naoki Yoneda; Osamu Hiroshima; Nobuyuki Mori; Hiroki Ishihara; Takashi Musha; Toshiyuki Matsuoka; Sachiyuki Hamano; Norio Minami
Journal of Medicinal Chemistry | 1991
Hitoshi Oinuma; Tadanobu Takamura; Takashi Hasegawa; Kenichi Nomoto; Toshihiko Naitoh; Yoshiharu Daiku; Sachiyuki Hamano; Hiroshi Kakisawa; Norio Minami
Synthesis | 1996
Shigeto Negi; Masayuki Matsukura; Masanori Mizuno; Kazutoshi Miyake; Norio Minami
Chemical & Pharmaceutical Bulletin | 1992
Masayuki Matsukura; Yoshiharu Daiku; Kouichirou Ueda; Satoru Tanaka; Toshiji Igarashi; Norio Minami
Archive | 1995
Noriyasu Hirose; Hiroshi Inoue; Toshio Matsunami; Takashi Yoshimura; Kouzou Morita; Yuh Horikawa; Noriyoshi Iwata; Norio Minami; Kenji Hayashi; Chiaki Seki
Archive | 1989
Norio Minami; Fumihiro Ozaki; Keiji Ishibashi; Yasuhiro Kabasawa; Megumi Ikemori; Toshiaki Ogawa; Takanori Kawamura
Archive | 1987
Hitoshi Oinuma; Motosuke Yamanaka; Kazutoshi Miyake; Tomonori Hoshiko; Norio Minami; Tadao Shoji; Yoshiharu Daiku; Kohei Sawada; Kenichi Nomoto
Archive | 1995
Kozo Akasaka; Masahiro Yonaga; Akiharu Kajiwara; Kunizo Higurashi; Kohshi Ueno; Satoshi Nagato; Makoto Komatsu; Noritaka Kitazawa; Masataka Ueno; Yoshiharu Yamanishi; Yoshimasa Machida; Yuki Komatsu; Naoyuki Shimomura; Norio Minami; Toshikazu Shimizu; Atsushi Nagaoka
Archive | 1987
Hitoshi Oinuma; Motosuke Yamanaka; Kazutoshi Miyake; Tomonori Hoshiko; Norio Minami; Tadao Shoji; Yoshiharu Daiku; Kohei Sawada; Kenichi Nomoto
