Kee-In Lee

Introduction of N‐Containing Heterocycles into Pyrazole by Nucleophilic Aromatic Substitution

Abstract The nucleophilic aromatic substitution on 5‐chloropyrazoles activated by the electron‐withdrawing formyl group offers a useful method to introduce a wide range of N‐containing heterocycles into them. The rate of reaction was greatly affected by the electronic nature of the N‐1 substitution.

Three‐Component Synthesis of 3‐Aminomethylene‐thiochroman‐2,4‐diones from 4‐Hydroxythiocoumarin

Abstract A three‐component synthesis of 3‐aminomethylene‐thiochroman‐2,4‐dione derivatives 2–22 by the condensation reactions of amines, α‐aminoacids, ureas, and carbamates with 4‐hydroxythiocoumarin 1, respectively, in the presence of triethyl orthofomate is described.