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Ken-ichi Haruna

Kyoto University

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Publication

Featured researches published by Ken-ichi Haruna.

Bioorganic & Medicinal Chemistry | 2013

Stepwise regulation of hole transport in DNA by control of triplex formation.

Ken-ichi Haruna; Haruka Iida; Sei-ichi Nishimoto; Kazuhito Tanabe

A functionality for regulating hole transport efficiency is a prerequisite for the utilization of DNA duplexes as nanodevices. Herein, we report the regulation of hole transport in anthraquinone-tethered DNA with dual triplex forming sites. Long-range photooxidation experiments showed that hole transport was effectively suppressed by the formation of triplex at low temperature, while it was recovered by dissociation to the duplex at higher temperature. Variation of temperature induced the formation and dissociation of the third strand at each triplex region individually, leading to the stepwise regulation of hole transport in DNA.

Journal of the American Chemical Society | 2006

Electrochemical Evaluation of Alternating Duplex-Triplex Conversion Effect on the Anthraquinone-Photoinjected Hole Transport through DNA Duplex Immobilized on a Gold Electrode

Kazuhito Tanabe; Haruka Iida; Ken-ichi Haruna; Taku Kamei; and Akimitsu Okamoto; Sei-ichi Nishimoto

Bioorganic & Medicinal Chemistry | 2006

Effects of structural modification on the DNA binding properties and photo-induced cleavage reactivity of propargylic sulfones conjugated with an anthraquinone structure

Ken-ichi Haruna; Hiroshi Kanezaki; Kazuhito Tanabe; Wei-Min Dai; Sei-ichi Nishimoto

Organic and Biomolecular Chemistry | 2008

Photoelectrochemical evaluation of pH effect on hole transport through triplex-forming DNA immobilized on a gold electrode

Ken-ichi Haruna; Haruka Iida; Kazuhito Tanabe; Sei-ichi Nishimoto

Bioorganic & Medicinal Chemistry | 2003

Photo-Induced DNA cleavage reaction characteristics of propargylic sulfones possessing anthraquinone chromophore

Ken-ichi Haruna; Kazuhito Tanabe; Atsushi Ishii; Wei Min-Dai; Hiroshi Hatta; Sei-ichi Nishimoto

Nucleic acids symposium series (2004) | 2007

Development of Novel Oxygen-Independent Photosensitizers

Zhouen Zhang; Ken-ichi Haruna; Takeo Ito; Hiroshi Hatta; Sei-ichi Nishimoto

Nucleic acids symposium series (2004) | 2005

Switching of charge transport in DNA by regulated triplex formations at the dual sites.

Ken-ichi Haruna; Kazuhito Tanabe; Haruka Iida; Sei-ichi Nishimoto

Nucleic acids symposium series (2004) | 2004

The effect of triple helix forming on charge transport in DNA

Ken-ichi Haruna; Kazuhito Tanabe; Haruka Iida; Hiroshi Hatta; Sei-ichi Nishimoto

Archive | 2004

Photo-induced DNA cleavage reaction characteristics of propargylic sulfones possessing anthraquinone chromophore (vol 11, pg 5311, 2003)

Ken-ichi Haruna; Kazuhito Tanabe; Atsushi Ishii; Wei-Min Dai; Hiroshi Hatta; Sei-ichi Nishimoto

Bioorganic & Medicinal Chemistry | 2004

Corrigendum to “Photo-induced DNA cleavage reaction characteristics of propargylic sulfones possessing anthraquinone chromophore”: [Bioorg. Med. Chem. 11 (2003) 5311–5316]

Ken-ichi Haruna; Kazuhito Tanabe; Atsushi Ishii; Wei-Min Dai; Hiroshi Hatta; Sei-ichi Nishimoto

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Sei-ichi Nishimoto

Kyoto University

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Kazuhito Tanabe

Kyoto University

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Hiroshi Hatta

Kyoto University

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Haruka Iida

Kyoto University

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Atsushi Ishii

Kyoto University

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Wei-Min Dai

Hong Kong University of Science and Technology

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Hiroshi Kanezaki

Kyoto University

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Takeo Ito

Kyoto University

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Taku Kamei

Kyoto University

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Zhouen Zhang

Kyoto University

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