Kenichi Shionoya

Aetiology of maxillofacial fracture

The aetiological factors associated with maxillofacial fractures, and the trends in these factors over a 13 year period are reported. The First Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Tokyo Medical and Dental University, managed 695 patients with maxillofacial fractures between 1977 and 1989. The male to female ratio was 3.2:1 and the majority of patients were aged between 10 and 30 years old. Road traffic accidents and accidental falls were the main causes of fractures throughout the 13 year study period. Mandibular fractures occurred in 477 patients (68.6%). A high percentage of patients were treated by closed reduction and maxillo-mandibular fixation, or occlusal splinting.

A Study of the Localization of Transferrin Receptor in Malignant Tumor Cells

In several studies, numerous microvilli were found on the surfaces of malignant tumor cells which had high growth potentials, and some tumor-related antigens were identified on these microvilli. Transferrin receptor (TfR) is expressed in proliferating cells and regarded as a tumor marker. In human carcinoma cell lines (HeLa cells, KB cells, and HSC-7 cells), significantly more microvilli were observed in the subconfluent phase than in the confluent phase. Also, TfR was found along the plasma membranes, especially well developed microvilli, coated pits, and coated vesicles in both phases by the immunoelectron microscopic method. These results indicate that the proliferative ability of the tumor cells might correlate with the development of microvilli.

A case of carotid body tumor.

頸動脈小体腫瘍は稀な疾患である。今回われわれは選択的頸動脈造影にて頸動脈小体腫瘍と診断可能であった1例について報告する。症例は, 43歳女性。頸部の無痛性腫瘤を主訴に, 1990年12月13日埼玉県立がんセンター口腔外科受診。選択的頸動脈造影にて, 腫瘍は血流に富み, 頸動脈分岐部に位置し, 栄養血管が外頸動脈の枝であることが明確となり, この所見より頸動脈小体腫瘍 (Shamblin I型) であると診断可能であった。腫瘍は全身麻酔下にて容易に摘出可能であった。病理組織学的には, 傍神経節腫であった。術後経過は良好である。