Kinai Tomita

Histopathologic study of bone invasion by DMBA-induced carcinoma of the mouth in the hamster

Carcinoma was induced in the floor of the mouth in the hamster, and the mechanism of bone invasion was studied microscopically. Conclusions are as follows: The periosteum is destroyed and, in general, the external surface of the cortical bone is resorbed through osteoclastic action. However, the periosteum at times resists the invasion of tumors. As the cortical bone is resorbed to some extent and tumor replaces the resorbed area, Volkmann and haversian canals begin to enlarge. Following enlargement of the canals, tumor invasion results in enlargement of the canals of the cortical bone far from the invaded area. In addition, tumors invade the periodontal space and resorb the inner surface of the alveolar bone. Tumors invade the bone marrow through the enlarged haversian canals or the periodontal space or by direct resorption of cortical bone, thus replacing the marrow spaces.

Compression therapy for parotid haemangioma in infants: A report of three cases

Summary Three cases of parotid haemangioma in infants are presented. Compression therapy was applied in these cases using a resin splint and a headcap and they were very effective. In the first case, the lesion had begun to reduce in volume within two weeks after starting the compression therapy. The haemangioma had disappeared completely in sixteen months. In the second and third cases, the lesions have disappeared in eight months and fifteen months, respectively. In all of the cases, no side effects were noticed. We believe that compression therapy is a safe and effective treatment modality for haemangiomas in infants even though these may disappear spontaneously in some cases.