Koji Satoh

Follicular dendritic cell tumor in the oro-pharyngeal region: report of a case and a review of the literature

A case of follicular dendritic cell tumor (FDC tumor) arised in the aro-pharyngeal region is reported in a 16-year-old Japanese boy. He had a swelling in the right retromolar trigone and soft palate. Clinical examination disclosed a 25 mm x 30 mm, elastic hard, ulcerated mass. CT scans showed a low density lesion in the right medial parapharyngeal area. The biopsy specimen revealed a low-grade malignant tumor. The patient underwent a tumorectomy which was extended to include the adjacent palatine tonsil. The tumor cells, with a clear cytoplasm and oval nucleus, were immunoreactive for S-100 (N/A), CD 21 (1F8), fascin (55K-2) and FDC (CNA42). The fascicular sheet pattern arrangement of the tumor cells was partly characteristic. The final diagnosis was an follicular dendritic cell tumor. Three courses of adjuvant chemoradiotherapy were administered postoperatively. Clinical features, pathological diagnosis and immunohistochemical markers for distinguishing FDC tumor are reviewed.

Local recurrence of sclerosing mucoepidermoid carcinoma with eosinophilia in the upper lip: a case report

IntroductionSclerosing mucoepidermoid carcinoma with eosinophilia is a rare morphological variant of thyroid carcinoma associated with Hashimoto’s disease. To date, only three such tumors have been reported in the minor salivary glands. We describe the first case, to the best of our knowledge, of recurrent sclerosing mucoepidermoid carcinoma with eosinophilia in the minor salivary glands of the upper lip.Case presentationA 61-year-old Japanese man was referred to our hospital with a mass in his median upper lip of four years’ duration. An examination of his median upper lip revealed a well-defined tumor measuring 9×12mm in diameter, which was subsequently resected. Three years after the first surgery, the tumor recurred and was resected. Both tumors were confirmed by histopathology to be sclerosing mucoepidermoid carcinoma with eosinophilia. Neither recurrence nor metastasis was observed in three and a half years of follow-up after the second surgery.ConclusionOur findings indicate that sclerosing mucoepidermoid carcinoma with eosinophilia can originate in the minor salivary glands and may be clinically or pathologically misdiagnosed as other conditions.

Successful Hemostasis after Dental Extraction with the Use of Recombinant Activated Factor VII in a Factor VII Deficient Patient

Abstract We report our experience of successful hemostasis after dental extraction with the use of rF VII a in a FVII deficient patient. Preoperative PT% was 25%, FVII was less than 3%. Thirty minutes before tooth extraction, 1.2 mg of rFVII a was injected. At the beginning of the operation, PT% was more than 200%, FVII was 336%, the hemostasis after dental extraction was excellent. rFVII a was used effectively and safely for dental extraction in this case of FVII deficiency.

Appropriate tongue blade width of the Dingman Mouth Gag for Japanese cleft palate patients with mandibular micrognathia

Objective: The purpose of this study is to determine the appropriate tongue blade width of Dingman Mouth Gag for Japanese cleft palate (CP) patients with mandibular micrognathia. Methods: We investigated 22 isolated CP patients whose bilateral lower first deciduous molars (D) had erupted. Patients were divided into the micrognathia (MG) group (10 patients) and normognathia (NG) group (12 patients). Following items were investigated: gender, age (A) and weight (W) at the time of surgery, distance between the top of lingual cusps of bilateral lower Ds (D1), distance between the lingual deepest points of bilateral lower Ds (D2) and perpendicular distance from the midpoint of incisal margin of bilateral lower deciduous central incisors to the line connecting the most distal points of bilateral lower Ds (D3). Results: There were significant differences in A and D3 between the groups. There were significant correlations between W and D3, D1and D3, D2 and D3 in the MG group. Excluding the attachment part to the mouth gag frame, we had assumption that the position 13.2 mm (equal to the median value of D3 in the MG group) posterior from the tip of the tongue blade would be corresponding to the D2 measurement point. The actual measured value for the small tongue blade width (D4) was 20.5 mm, smaller than median value of D2 in the MG group. Conclusions: We conclude the width of small tongue blade of Dingman Mouse Gag currently in use may be appropriate and no modification is required for the width. Correspondence to: Koji Satoh, Department of Dentistry and Oral Maxillofacial Surgery, School of Medicine, Fujita Health University, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan, Tel: +81-562-93-9258, Fax: +81562-93-9258, E-mail: kjsato@fujita-hu.ac.jp

Appropriate Tongue Blade Length of the Dingman Mouth Gag for Japanese Pediatric Patients With Cleft Palate and Mandibular Micrognathia

Objective Our objective is to determine appropriate specifications for smaller tongue blade for Japanese pediatric patients with cleft palate (CP) and mandibular micrognathia. Patients We investigated 59 patients who underwent palatoplasty. Patients were divided into two groups: the micrognathia (MG) group consisted of 11 patients and the normognathia (NG) group consisted of 48 patients. Interventions The following five items were investigated retrospectively: (1) gender, (2) cleft type, (3) age at the time of surgery, (4) weight at the time of surgery, and (5) distance from the tongue blade base to the posterior pharyngeal wall (Dis). Result There was a significant difference (P < .01) in age at the time of surgery and in Dis between groups, but not in weight. The minimum values were 55 mm for the MG group. As for correlations between age and weight at the time of surgery, the P values for the MG and NG groups were .993 and .052, respectively. As for correlations between weight at the time of surgery and Dis, the P values for the MG and NG groups were .987 and .099, respectively. Conclusions It was difficult to predict Dis on the basis of the patients age and weight measured preoperatively. The minimum Dis was 55 mm, equal to the length from the base to the tip of the Dingman Mouth Gag tongue blade currently in use, suggesting that a tongue blade of approximately 50 mm in length, shorter than the current minimum specifications, may be appropriate.

Osteogenesis Imperfecta Diagnosed from Mandibular and Lower Limb Fractures: A Case Report

Osteogenesis imperfecta (OI) is a congenital disease characterized by bone fragility and low bone mass. Despite the variety of its manifestation and severity, facial fractures occur very infrequently. Here, we report a case of an infant diagnosed with OI after mandibular and lower limb fractures. A boy aged 1 year and 3 months was brought to his neighboring hospital with a complaint of facial injury. He was transferred to our hospital to undergo operation 3 days later. Computed tomography images revealed multiple mandibular fractures including complete fracture in the symphysis and dislocated condylar fracture on the right side. Open reduction and internal fixation with absorbable implants was performed 7 days after injury. He fractured his right lower limb 2 months later. He was diagnosed with OI type IA by an orthopedist. He will be administered bone-modifying agents if he suffers from frequent fractures.