Kongara Ravinder Reddy

Multifidone: a novel cytotoxic lathyrane-type diterpene having an unusual six-membered A ring from Jatropha multifida.

Chemical examination of the stems of Jatropha multifida afforded a novel lathyrane-type diterpene, multifidone, having an unusual six-membered A ring. The structure of the compound was determined from detailed analysis of its 1D and 2D NMR spectra and X-ray crystallographic analysis. Its cytotoxicity was measured on four different cancerous cell lines.

Diterpenoids from Jatropha multifida

Chemical investigation on the stems of Jatropha multifida yielded two diterpenoids, multifolone and (4E)-jatrogrossidentadione acetate along with five known diterpenoids, a flavone and a coumarino-lignan. The structures of the compounds were settled by detailed analysis of their 1D and 2D NMR spectra. The X-ray crystallographic analysis of (4E)-jatrogrossidentadione acetate was also accomplished.

Perchloric acid adsorbed on silica gel : an efficient heterogeneous reusable catalyst for synthesis of 1,5-benzodiazepines

The condensation of o-phenylenediamines with both aliphatic (acyclic and cylic) and aromatic ketones has been carried out to produce 1,5-benzodiazepines in high yields using perchloric acid adsorbed on silica gel as a heterogeneous catalyst. The catalyst can be recycled.