Publication


Featured researches published by Koshirou Hioki.


Archive | 1993

HLA-DR Expression on Cancer Cells and T Cell Reaction in Colorectal Carcinoma

Kanji Tanaka; Mika Morita; Shigeo Okamura; Tokio Okusa; Yasushi Nakane; Hideho Takada; Koshirou Hioki

60 cases of colorectal adenocarcinoma were immunohistochemically examined to clarify the relationship between HLA - DR expression on tumor cells and T cell infiltration. The more HLA-DR+ cancer cells in the carcinoma tissue increased, the more T cells tended to aggregate in both the infiltrating front of cancer tissue and the intracarcinomatuos stroma. We speculate that HLA - DR antigen on cancer cells might be immunoreactive and seems to be closely related with the cellular immunity in colorectal carcinoma.


Archive | 1993

Immunohistochemical Study of the Expression of HLA-DR Antigen and Lymphocyte Infiltration in Human Esophageal Carcinoma

Kanji Tanaka; Mika Morita; Takayuki Motohiro; Hideharu Yamanaka; Yasushi Nakane; Koshirou Hioki

The major histocompatibility complex (MHC) class II antigen HLA-DR is known to be present on many types of immunocompetent cells, involved in a variety of immune functions, and can be found in various kinds of cancer cells of the gastrointestinal tract. It is also reported that HLA-DR is associated with tumor invasion, tumor metastasis, and patient survival [1].


British Journal of Surgery | 1990

Surgical strategy for early gastric cancer

Koshirou Hioki; Yasushi Nakane; Masakatsu Yamamoto


International Journal of Cancer | 2007

PLASMINOGEN ACTIVATORS IN HUMAN GASTRIC CANCERS : CORRELATION WITH DNA PLOIDY AND IMMUNOHISTOCHEMICAL STAINING

Souichirou Takai; Manabu Yamamura; Kanji Tanaka; Hiroshi Kawanishi; Masazumi Tsuji; Yasushi Nakane; Koshirou Hioki; Masakatsu Yamamoto


Journal of Surgical Oncology | 1991

Expression of HLA-DR and secretory component antigens and lymphocyte infiltration in human gastric nonmalignant and malignant tissues: an immunohistochemical study.

Noburo Hirozane; Kanji Tanaka; Yasushi Nakane; Manabu Yamamura; Koshirou Hioki; Hiroshi Nagura; Masakatsu Yamamoto


Journal of Surgical Oncology | 1991

Immunohistochemical analysis of plasminogen activator expression in human colorectal carcinomas: correlation with CEA distribution and tumor cell kinetics.

Hiroshi Kawanishi; Kanji Tanaka; Souichirou Takai; Hideho Takada; Manabu Yamamura; Koshirou Hioki; Hiroshi Nagura; Masakatsu Yamamoto


Journal of Surgical Oncology | 1990

Immunohistochemical analysis of the relationship between CEA localization and mononuclear cell infiltration in human colorectal carcinoma

Kanji Tanaka; Hiroshi Nagura; Yoshinori Hamada; Manabu Yamamura; Koshirou Hioki; Keiichi Watanabe; Masakatsu Yamamoto


Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 1994

A CASE OF BENIGN SYMMETRICAL LIPOMATOSIS

Mika Morita; Kanji Tanaka; Koshirou Hioki


Nihon Rinsho Geka Gakkai Zasshi (journal of Japan Surgical Association) | 1993

TWO CASES OF CHILD AND ADULT INTUSSUSCEPTION DIAGNOSED BY COMPUTED TOMOGRAPHY

Mika Morita; Kuniyuki Nakagawa; Nobumichi Hosoda; Takashi Koreeda; Koshirou Hioki


Acta Histochemica Et Cytochemica | 1992

New Lead Citrate Method for 5′-Nucl eoti dase Enzyme Cytochemistry. -Development and its application on rat the retina-.

M. Okayama; T. Saito; Minoru Okuda; Yuji Oishi; Hideki Takahashi; Tetsuji Syoji; Airo Tubura; Toshiyuki Fujii; Sotokichi Morii; Munehiko Onda; Takeo Aida; Toshiyuki Ishiwata; Goro Asano; Tatsuki Oyaizu; Hideto Senzaki; S. Razzaque; T. Taguchi; N. Saito; M. Shimada; Toshihiro Maeda; Naoaki Saito; Akiko Itouji; Yoshiki Totani; Chikako Tanaka; Taichiro Sakurai; Kouji Kameyama; Noriaki Sato; Masakazu Ishikawa; Mitsuo Nakai; Koji Kami

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