Kristen M. Young
Beth Israel Deaconess Medical Center
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Publication
Featured researches published by Kristen M. Young.
Allergy | 2013
Revital Shamri; Kristen M. Young; Peter F. Weller
Eosinophils have the capacity to secrete varied cytotoxic proteins. Among the proteins are the eosinophil‐associated RNases (EARs): the human eosinophil‐derived neurotoxin and eosinophilic cationic protein, and their murine ortholog EARs, which have been shown to be involved in host defense, tissue remodeling, and immunity regulation. However, the signal transduction that regulates EARs secretion in response to physiological stimuli, such as chemokines, has been little studied in human and scarcely in mouse eosinophils, the foremost animal model for eosinophil‐associated human diseases.
Clinical & Experimental Allergy | 2018
Revital Shamri; Kristen M. Young; Peter F. Weller
Eosinophil‐associated RNases (EARs) are stored preformed in eosinophil cytoplasmic secretory granules and have a key role in eosinophil effector functions in host defence and inflammatory disorders. However, the secretion mechanisms of EARs are poorly understood.
Archive | 2015
T. Kuriyama; H. Tani; A. Masuda; Toshio Kobayashi; H. Kimura; S. Masuyama; Ryan W. Bavis; Gordon S. Mitchell; Fabiola León-Velarde; Alfredo Gamboa; Maria Rivera-Ch; Jose-Antonio Palacios; A Peter; Kristen M. Young; Kevin J. Barry; Matthew R. Boller; Eugene Kim; M Peter
Archive | 2015
Qiuli Liu; Charles Fehring; T. F. Lowry; Margaret T. T. Wong-Riley; Alida R. Ovrutsky; Donna A. Rampersad; Ryan W. Bavis; Kristen M. Young; Kevin J. Barry; Matthew R. Boller; Eugene Kim; Catherine A. Mayer; J. M. Di Fiore; Richard J. Martin; Peter M. MacFarlane; Jianguo Zhuang; Lei Zhao; Fadi Xu
Archive | 2015
Gregory M. Blain; Curtis A. Smith; Kathleen S. Henderson; A Jerome; Ryan W. Bavis; Kristen M. Young; Kevin J. Barry; Matthew R. Boller; Eugene Kim; M Peter; Christo Goridis; Pierre-Louis Ruffault; Boris Matrot; Gilles Fortin; Jean-François Brunet; Marie-Rose Hirsch; Muriel Thoby-Brisson; Véronique Dubreuil; Jerome A. Dempsey
Journal of Immunology | 2012
Revital Shamri; Kristen M. Young; Peter F. Weller
The Journal of Allergy and Clinical Immunology | 2011
Jason J. Xenakis; Amy L. Radke; Kristen M. Young; Rossana C. N. Melo; Lisa A. Spencer
Journal of Immunology | 2011
Revital Shamri; Kristen M. Young; Rossana C. N. Melo; Ionita Ghiran; Peter F. Weller
The FASEB Journal | 2010
Ryan W. Bavis; Elizabeth F. Dmitrieff; Kristen M. Young; Samantha E. Piro
The FASEB Journal | 2009
Kristen A Meyers; Kristen M. Young; Ryan W. Bavis