Kuldip Gupta

Epidemiological Studies on Canine Mammary Tumour and its Relevance for Breast Cancer Studies

Breast cancer is the most common cancer in women. Its incidence is rising globally and more so in the developing countries. There is a need to look for suitable animal model for biomedical research and pharmaceutical trails for this dreadly disease. In this pursuit, huge naturally occurring resource of canine mammary tumour may provide valid answer to impending questions in a shorter time frame. However, the epidemiology of canine mammary tumour (CMT) is poorly documented, especially in India. The present review deals with global and Indian scenario related to epidemiology of canine mammary tumour and its relevance as a model for human breast cancer.

Hematological changes in neonatal diarrheic calves of different age groups

The study was conducted on 100 neonatal calves of different age groups suffering from diarrhoea to identify any changes in the hematology. Hemoglobin levels of the affected calves of every age group were significantly decreased (p<0.01) as compared to corresponding control group. PCV values of 22–30 and 31–60 days diseased age groups were significantly (p<0.01) decreased but were not significantly different from the respective controls in other age groups. Significant leukocytosis, neutrophilia and lymphopenia were observed in diseased groups.

Serum biochemical changes in neonatal diarrhoeic calves of different age groups

This study was conducted on 100 neonatal calves of different age groups suffering from diarrhoea to see changes in some serum proteins and minerals. Serum albumin of 15–21 days diseased calves was significantly higher (p<0.05), whereas globulins concentration of 8–14 and 31–60 days diseased groups were significantly decreased as compared to corresponding control group. Calcium and phosphorus levels were significantly higher (p<0.05) in diarrheic calves of 1–7 days age group as compared to control. However, significant hypophosphatemia as well as hypomagnesaemia was seen in the older diarrhoeic calves of 31–60 days age.