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Dive into the research topics where Kumiko Kurabayashi is active.

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Featured researches published by Kumiko Kurabayashi.


Antimicrobial Agents and Chemotherapy | 2006

Gatifloxacin Resistance and Mutations in gyrA after Unsuccessful Helicobacter pylori Eradication in Japan

Toshihiro Nishizawa; Hidekazu Suzuki; Kumiko Kurabayashi; Tatsuhiro Masaoka; Hiroe Muraoka; Mikiji Mori; Eisuke Iwasaki; Intetsu Kobayashi; Toshifumi Hibi

ABSTRACT A high resistance rate (47.9%) to gatifloxacin (GAT; 8-methoxy fluoroquinolone) in Helicobacter pylori (H. pylori) strains from 48 Japanese patients is observed after unsuccessful H. pylori eradication. A significant association between MICs for GAT equal to or above 1 μg/ml and mutations of the gyrA gene of H. pylori was demonstrated.


Helicobacter | 2005

Effect of dietary anti-urease immunoglobulin Y on Helicobacter pylori infection in Mongolian gerbils.

Sachiko Nomura; Hidekazu Suzuki; Tatsuhiro Masaoka; Kumiko Kurabayashi; Hiromasa Ishii; Masaki Kitajima; Kikuo Nomoto; Toshifumi Hibi

Background and aim.  Helicobacter pylori is known to be a major pathogenic factor in the development of gastritis, peptic ulcer disease and gastric cancer. Recently, chicken egg yolk immunoglobulin Y (IgY) has been recognized as an inexpensive antibody source for passive immunization against gastrointestinal infections. The present study was designed to investigate the effect of anti‐urease IgY on H. pylori infection in Mongolian gerbils.


Alimentary Pharmacology & Therapeutics | 2004

Second-line treatment of Helicobacter pylori infection after dilution agar methods and PCR-RFLP analysis

T. Masaoka; Hidekazu Suzuki; Kumiko Kurabayashi; A. G. Kamiya; Hiromasa Ishii

Background : After unsuccessful first‐line treatment of Helicobacter pylori infection, the percentage of clarithromycin‐resistant strains has been reported as between 30% and 70% in Japan and other countries. A high prevalence of clarithromycin‐resistant strains is reported to be associated with eradication failure.


Alimentary Pharmacology & Therapeutics | 2007

Could frameshift mutations in the frxA and rdxA genes of Helicobacter pylori be a marker for metronidazole resistance?: FRXA AND RDXA GENES TO METRONIDAZOLE RESISTANCE IN H. PYLORI

T. Masaoka; Hidekazu Suzuki; Kumiko Kurabayashi; Y. Nomoto; Toshihiro Nishizawa; Mikiji Mori; Taizo Hibi

Although resistance of Helicobacter pylori to metronidazole had been reported to be associated with mutations in the rdxA or the frxA gene, recent studies have indicated that they may contribute little to metronidazole resistance.


World Journal of Gastroenterology | 2005

Enhanced plasma ghrelin levels in Helicobacter pylori-colonized, interleukin-1-receptor type 1-homozygous knockout (IL-1R1-/-) mice

Yuka Abiko; Hidekazu Suzuki; Tatsuhiro Masaoka; Sachiko Nomura; Kumiko Kurabayashi; Hiroshi Hosoda; Kenji Kangawa; Toshifumi Hibi


The Keio Journal of Medicine | 2003

Current consensus on the diagnosis and treatment of H. pylori-associated gastroduodenal disease

Hidekazu Suzuki; Tatsuhiro Masaoka; Sachiko Nomura; Yoshinori Hoshino; Kumiko Kurabayashi; Yuriko Minegishi; Masayuki Suzuki; Hiromasa Ishii


Alimentary Pharmacology & Therapeutics | 2006

Could frameshift mutations in the frxA and rdxA genes of Helicobacter pylori be a marker for metronidazole resistance

Tatsuhiro Masaoka; Hidekazu Suzuki; Kumiko Kurabayashi; Y. Nomoto; Toshihiro Nishizawa; Mikiji Mori; Toshifumi Hibi


Nihon rinsho. Japanese journal of clinical medicine | 2005

H. pylori motility analysis

Hidekazu Suzuki; Kumiko Kurabayashi; Toshifumi Hibi


Gastroenterology | 2003

The effectiveness of antibiotic susceptibility test by dilution agar methods and detection of pointmutations in the 235 ribosomal RNA before second-line treatement of Helicobacter pylori infection

Tatsuhiro Masaoka; Hidekazu Suzuki; Kumiko Kurabayashi; Akitoshi Kamiya; Hiromasa Ishii


Gastroenterology | 2003

Attenuated apoptosis in the inflamed gastric mucosa of H.Pylori colonized iNOS knockout mice

Hidekazu Suzuki; Masaharu Miyazawa; Tatsuhiro Masaoka; Sachiko Nomura; Kumiko Kurabayashi; Hiroshi Nagata; Soichiro Miura; Hiromasa Ishii

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