L. H. Sobin

Histological typing of ovarian tumours

Histological Classification of Ovarian Tumours.- Definitions and Explanatory Notes.- Surface-Epithelial Stromal Tumours.- Sex Cord-Stromal Tumours.- Germ Cell Tumours.- Gonadoblastoma.- Germ Cell-Sex Cord-Stromal Tumour of Non-gonadoblastoma Type.- Tumours of Rete Ovarii.- Mesothelial Tumours.- Tumours of Uncertain Origin and Miscellaneous Tumours.- Gestational Trophoblastic Disease.- Soft Tissue Tumours Not Specific to Ovary.- Malignant Lymphomas, Leukaemias and Plasmacytoma.- Unclassified Tumours.- Secondary (Metastatic) Tumours.- Tumour-like Lesions.- TNM Classification of Tumours of the Ovary.- Illustrations.

Histological typing of intestinal tumours

Introduction Histological Classification of Intestinal Tumours Small Intestine Appendix Large Intestine Anal Canal Anal Margin Definitions and Explanatory Notes Small Intestine Appendix Large Intestine Anal Canal Anal Margin Subject Index

Histological typing of tumours of the liver

Introduction Histological Classification of Tumours of the Liver Definitions and Explanatory Notes Epithelial Tumours Nonepithelial Tumours Miscellaneous Tumours Unclassified Tumours Haemopoietic and Lymphoid Tumours Metastatic Tumours Epithelial Abnormalities Tumour-like Lesions TNM Classification of Tumours of the Liver Illustrations Subject Index

Colon and Rectum

Carcinoma of the large intestine has undergone relatively few basic modifications between the 6th and 7th TNM editions so that the main T, N, and M categories and Stages I, II, III, and IV can be compared with those of the previous two editions. A number of subdivisions of these major categories have been made. Despite this expansion, all of the substages can be collapsed back into the original four stages of previous TNM classifications covering a 30 year span as well as being compatible with the original Dukes classification, thus ensuring backwards compatibility.

Histological Classification of Tumours

“Classification is fundamental to the quantitative study of any phenomenon. It is recognized as the basis of all scientific generalization and is therefore an essential element in statistical methodology. Uniform definitions and uniform systems of classification are prerequisites in the advancement of scientific knowledge.”1

Breast Tumours (ICD-O C50)

The classification applies only to carcinomas. There should be histological confirmation of the disease. The anatomical subsite of origin should be recorded but is not considered in classification.

TNM Classification of Tumours of the Liver

The classification applies only to primary hepatocellular and cholangio- (intrahepatic bile duct) carcinoma of the liver. There should be histological confirmation of the disease.

Tumoren der Knochen und Weichteile

Regionar sind diejenigen Lymphknoten, die der Lage des Primartumors entsprechen (siehe Abb. 470, S. 359).

Lungen- und Pleuratumoren

Die Klassifikation gilt nur fur Karzinome der Lunge und das maligne Mesotheliom der Pleura.

Residualtumor-(R-)Klassifikation

Das Fehlen oder Vorhandensein von Residualtumor (Resttumor) nach Behandlung wird durch die R-Klassifikation beschrieben. Ihre Verwendung ist fakultativ.* TNM und pTNM beschreiben die anatomische Ausbreitung des Tumors (ausgenommen beim Retinoblastom) ohne Berucksichtigung der Behandlung. Sie konnen erganzt werden durch die R-Klassifikation, die den Tumorstatus nach Behandlung erfast. Sie spiegelt die Effekte der Therapie wider, beeinflust das weitere therapeutische Vorgehen und liefert die zuverlassigsten Voraussagen zur Prognose.