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Dive into the research topics where Larry R. Miller is active.

Publication


Featured researches published by Larry R. Miller.


Bioorganic & Medicinal Chemistry Letters | 2005

P2-P3 conformationally constrained ketoamide-based inhibitors of cathepsin K.

David G. Barrett; Virginia M. Boncek; John G. Catalano; David N. Deaton; Anne M. Hassell; Cynthia Holder Jurgensen; Stacey T. Long; Robert B. McFadyen; Aaron B. Miller; Larry R. Miller; J. Alan Payne; John A. Ray; Vicente Samano; Lisa M. Shewchuk; Francis X. Tavares; Kevin J. Wells-Knecht; Derril H. Willard; Lois L. Wright; Hui-Qiang Q. Zhou


Bioorganic & Medicinal Chemistry Letters | 2005

Novel and potent cyclic cyanamide-based cathepsin K inhibitors.

David N. Deaton; Anne M. Hassell; Robert B. McFadyen; Aaron B. Miller; Larry R. Miller; Lisa M. Shewchuk; Francis X. Tavares; Derril H. Willard; Lois L. Wright


Bioorganic & Medicinal Chemistry Letters | 2004

Exploration of the P1 SAR of aldehyde cathepsin K inhibitors

John G. Catalano; David N. Deaton; Eric S. Furfine; A.M Hassell; Robert B. McFadyen; Aaron B. Miller; Larry R. Miller; Lisa M. Shewchuk; Derril H. Willard; Lois L. Wright


Bioorganic & Medicinal Chemistry Letters | 2004

Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions.

David G. Barrett; John G. Catalano; David N. Deaton; Anne M. Hassell; Stacey T. Long; Aaron B. Miller; Larry R. Miller; Lisa M. Shewchuk; Kevin J. Wells-Knecht; Derril H. Willard; Lois L. Wright


Bioorganic & Medicinal Chemistry Letters | 2004

Design of small molecule ketoamide-based inhibitors of cathepsin K

John G. Catalano; David N. Deaton; Stacey T. Long; Robert B. McFadyen; Larry R. Miller; J. Alan Payne; Kevin J. Wells-Knecht; Lois L. Wright


Bioorganic & Medicinal Chemistry Letters | 2005

Acyclic cyanamide-based inhibitors of cathepsin K.

David G. Barrett; David N. Deaton; Anne M. Hassell; Robert B. McFadyen; Aaron B. Miller; Larry R. Miller; J. Alan Payne; Lisa M. Shewchuk; Derril H. Willard; Lois L. Wright


Bioorganic & Medicinal Chemistry Letters | 2006

Novel, potent P2-P3 pyrrolidine derivatives of ketoamide-based cathepsin K inhibitors.

David G. Barrett; John G. Catalano; David N. Deaton; Anne M. Hassell; Stacey T. Long; Aaron B. Miller; Larry R. Miller; John A. Ray; Vicente Samano; Lisa M. Shewchuk; Kevin J. Wells-Knecht; Derril H. Willard; Lois L. Wright


Bioorganic & Medicinal Chemistry Letters | 2004

Orally bioavailable small molecule ketoamide-based inhibitors of cathepsin K.

David G. Barrett; John G. Catalano; David N. Deaton; Stacey T. Long; Larry R. Miller; Francis X. Tavares; Kevin J. Wells-Knecht; Lois L. Wright; Hui-Qiang Q. Zhou


Bioorganic & Medicinal Chemistry Letters | 2006

Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?

Kim K. Adkison; David G. Barrett; David N. Deaton; Robert T. Gampe; Anne M. Hassell; Stacey T. Long; Robert B. McFadyen; Aaron B. Miller; Larry R. Miller; J. Alan Payne; Lisa M. Shewchuk; Kevin J. Wells-Knecht; Derril H. Willard; Lois L. Wright


Bioorganic & Medicinal Chemistry Letters | 2005

Ketoheterocycle-based inhibitors of cathepsin K: a novel entry into the synthesis of peptidic ketoheterocycles.

Francis X. Tavares; David N. Deaton; Aaron B. Miller; Larry R. Miller; Lois L. Wright

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