Lars Flataker
Merck & Co.
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Lars Flataker.
Experimental Biology and Medicine | 1956
Charles A. Winter; Lars Flataker
Summary 1) A syndrome resulting from intraperitoneal injection of LSD in rats is described. In rats trained to climb a rope, LSD produces signs of confusion and markedly prolongs climbing time. This effect on climbing time can be objectively and quantitatively measured, and is linearly related to the log dose of LSD. 2) Effects of LSD could be partially antagonized by serotonin or by 5-hydroxy tryptophane administered intra-peritoneally. α-4 (piperidyl) benzhydrol did not affect the action of LSD, while reserpine intensified and prolonged the LSD-syndrome.
Experimental Biology and Medicine | 1952
Charles A. Winter; Lars Flataker
Summary A method is described for testing antitussive activity in dogs. It is shown that 2 compounds nearly devoid of analgesic or narcotic properties, d-methadone and d-isomethadone, are active in this test.
Experimental Biology and Medicine | 1952
Charles A. Winter; Lars Flataker
Summary 1. Measurements have been made of the resistance offered by the skin to the intracutaneous introduction of fluid, as determined by the amount of pressure required to perform an intracutaneous injection under carefully controlled conditions in adult male rats. 2. Systemic administration of cortisone markedly increased the resistance of the skin to injection. Hyaluronidase, incorporated in the fluid administered intracutaneously, lowered the injection pressure. The effect of cortisone, however, was shown to be independent of the effect of the steroid upon hyaluronidase. Testosterone, desoxycorticosterone, compound S, and 21-acetoxypregnenolone were without effect under the conditions of these experiments.
Journal of Pharmacology and Experimental Therapeutics | 1965
Charles A. Winter; Lars Flataker
Journal of Pharmacology and Experimental Therapeutics | 1951
Charles A. Winter; Lars Flataker
Journal of Pharmacology and Experimental Therapeutics | 1965
Charles A. Winter; Lars Flataker
Journal of Pharmacology and Experimental Therapeutics | 1950
Charles A. Winter; Lars Flataker
Journal of Pharmacology and Experimental Therapeutics | 1954
Charles A. Winter; Lars Flataker
Journal of Pharmacology and Experimental Therapeutics | 1951
Charles A. Winter; Lars Flataker
Journal of Nervous and Mental Disease | 1958
Charles A. Winter; Lars Flataker