Lee E. F. Graves

Comparison of energy expenditure in adolescents when playing new generation and sedentary computer games: cross sectional study

Objective To compare the energy expenditure of adolescents when playing sedentary and new generation active computer games. Design Cross sectional comparison of four computer games. Setting Research laboratories. Participants Six boys and five girls aged 13-15 years. Procedure Participants were fitted with a monitoring device validated to predict energy expenditure. They played four computer games for 15 minutes each. One of the games was sedentary (XBOX 360) and the other three were active (Wii Sports). Main outcome measure Predicted energy expenditure, compared using repeated measures analysis of variance. Results Mean (standard deviation) predicted energy expenditure when playing Wii Sports bowling (190.6 (22.2) kJ/kg/min), tennis (202.5 (31.5) kJ/kg/min), and boxing (198.1 (33.9) kJ/kg/min) was significantly greater than when playing sedentary games (125.5 (13.7) kJ/kg/min) (P<0.001). Predicted energy expenditure was at least 65.1 (95% confidence interval 47.3 to 82.9) kJ/kg/min greater when playing active rather than sedentary games. Conclusions Playing new generation active computer games uses significantly more energy than playing sedentary computer games but not as much energy as playing the sport itself. The energy used when playing active Wii Sports games was not of high enough intensity to contribute towards the recommended daily amount of exercise in children.

The contribution of upper limb and total body movement to adolescents’ energy expenditure whilst playing Nintendo Wii

Little research documents the contribution of upper limb and total body movement to energy expenditure (EE) during active video gaming. To address this, EE, heart rate (HR), and, upper limb and total body movement were assessed in 11- to 17-year-old adolescents whilst playing three active (Nintendo Wii) and one sedentary (XBOX 360) video games. Non-dominant upper limb activity, EE and HR were significantly greater during Wii Sports boxing [mean 267.2 (SD 115.8) J kg−1 min−1; 136.7 (24.5) beats min−1] than tennis or bowling (P ≤ 0.044). For all active games hip activity best predicted EE (R2 ≥ 0.53), with two-measure models of HR and single-site activity data, and multi-site activity data, similarly explaining the variance in EE (R2 ≥ 0.64). The physiological cost of upper-body orientated active video games increased when movement of both upper limbs was encouraged. Improvements in EE explanatory power provide support for multi-site activity monitoring during unique, non-ambulatory activities.

Relationships between measures of fitness, physical activity, body composition and vascular function in children.

BACKGROUND The prevalence of obesity and physical inactivity in Western countries has increased rapidly. Both are modifiable risk factors for cardiovascular disease. Atherosclerosis begins in childhood and endothelial dysfunction is its earliest detectable manifestation. METHODS We assessed flow-mediated dilation (FMD) in 129 children (75 female; 10.3+0.3 yrs; 54 male; 10.4; 0.3 yrs). FMD was normalised for differences in the eliciting shear rate stimulus between subjects (SR(AUC)). Fitness was assessed as peak oxygen uptake during an incremental treadmill exercise test (V O(2)peak). Body composition was measured using a dual-energy X-ray absorptiometry (DEXA) scan. Physical activity (PA) was assessed using Actigraph accelerometers. The cohort was split into tertiles according to FMD% and also FMD% corrected for SR(AUC) to gain insight into the determinants of vascular function. RESULTS Across the cohort, significant correlations were observed between FMD%/SR(AUC) and DEXA percentage fat (r=-0.23, p=0.009) and percentage lean mass (r=0.21, p=0.008), and also with PA performed at moderate-to-high intensity (r=0.363, p=0.001). For children in the lowest FMD%/SR(AUC) tertile, a stronger relationship with all PA measures was observed, particularly with high intensity PA (r=0.572, P=0.003). Regression analysis revealed that high intensity PA was the only predictor of impaired FMD%/SR(AUC). CONCLUSIONS These data suggest that traditional risk factors for CHD in adult populations impact upon vascular function in young people. Furthermore, it appears that individuals with impaired FMD may benefit from performing high intensity PA, whereas no relationships exist between FMD and lower intensities of PA or between PA and FMD in those subjects who possess preserved vascular function a priori.

Physical activity, cardiorespiratory fitness, and clustered cardiometabolic risk in 10- to 12-year-old school children: The REACH Y6 study

(1) Investigate whether clustered cardiometabolic risk score, cardiorespiratory fitness (CRF), sedentary time (ST), and body mass index Z‐scores (BMI Z‐scores), differed between participants that met and did not achieve ≥60 min of daily moderate to vigorous intensity physical activity (MVPA). (2) Compare clustered cardiometabolic risk score, BMI Z‐score, ST, and MVPA by CRF status.

Heritability of Arterial Function, Fitness, and Physical Activity in Youth: A Study of Monozygotic and Dizygotic Twins

OBJECTIVES To examine the role of heredity in determining flow-mediated dilation in young people by comparing conduit artery endothelial function in monozygotic and dizygotic twins. We also determined relationships between physical activity and fitness in each twin subset. STUDY DESIGN Flow-mediated dilation was assessed with high-resolution ultrasonography of the brachial artery in 22 twin pairs (11 monozygotic pairs 13.3 ± 1.6 years, 11 dizygotic pairs 13.6 ± 1.6 years). Fitness was assessed as peak oxygen uptake during an incremental treadmill test. Physical activity was measured with accelerometry. Twin versus twin intraclass correlations were performed for both groups. RESULTS Flow-mediated dilation was significantly correlated in monozygotic twins only (r = 0.60, P = .02). Heritability of flow-mediated dilation was estimated at 0.44. Total PA time (monozygotic r = 0.77, dizygotic r = 0.60, P < .05) and light physical activity time (monozygotic r = 0.67, dizygotic r = 0.63, P < .05) correlated significantly in both groups. The peak oxygen uptake (r = 0.84, P < .01) was correlated only in monozygotic twins. CONCLUSION Genetic factors appear to be responsible for a modest portion of the flow-mediated dilation response, suggesting that flow-mediated dilation can be influenced by environmental factors.

Scaling of Peak Oxygen Uptake in Children: A Comparison of Three Body Size Index Models.

PURPOSE We aimed to compare three candidate body size index models for the scaling of aerobic fitness (V(˙)O(2peak)) in children: whole body mass, total lean body mass, and the lean mass of both legs. METHODS V(˙)O(2peak) and total lean mass of the body and both legs (via dual-energy x-ray absorptiometry) were assessed in 126 girls and 87 boys aged 9-11 yr. We applied nonlinear allometric models of the form V(˙)O(2peak) = a×body size, adjusted for biological sex and maturity offset (years from peak height velocity). We assessed goodness of fit using the Akaike information criterion. RESULTS The Akaike weights (Akaike differences) were as follows: lean mass of both legs = 0.69 (0), total lean body mass = 0.31 (1.6), and whole body mass = <1e-8 (36.6). The size exponent (90% confidence interval) for the lean mass of both legs was 0.55 (0.46-0.64). V(˙)O(2peak) was 17% (13%-21%) lower in girls after controlling for the lean mass of both legs and maturity offset. After controlling for body size and sex, a 1-yr increase in maturity offset (closer to peak height velocity) was associated with a 6% (4%-9%) higher V(˙)O(2peak). CONCLUSIONS Allometric scaling of V(˙)O(2peak) by the lean mass of both legs provides the best model for quantifying growth-related changes in aerobic fitness in pediatric populations, although this model is only marginally superior to the total lean body mass model. There is no support for the total body mass model. Maturity and sex are also important covariates exerting a size-independent influence on peak aerobic fitness.

Seasonal Reduction in Physical Activity and Flow-Mediated Dilation in Children

PURPOSE cardiovascular disease is a process that has its origins in childhood. Endothelial dysfunction is the earliest detectable manifestation of cardiovascular disease. This study aimed to assess the impact of seasonal changes in physical activity (PA) and body composition on conduit artery endothelial function in children. METHOD we studied 116 children (70 girls aged 10.7 ± 0.3 yr and 46 boys aged 10.7 ± 0.3 yr) on two occasions; in the northern summer (June) and late autumn (November). We assessed flow-mediated dilation (FMD) using high-resolution Doppler ultrasound. Body composition was measured by dual-energy x-ray absorptiometry. PA was assessed using accelerometry. RESULTS FMD (10.0% ± 4.3% to 7.9% ± 3.9%, P < 0.001) and PA (94.1 ± 34.8 to 77.8 ± 33.7 min·d, P < 0.01) decreased, while percentage body fat increased (27.6% ± 6.8% to 28.0% ± 6.6%, P < 0.001) between summer and autumn. Decreases in FMD correlated with decreases in high-intensity PA (r = 0.23, P = 0.04), and change in high-intensity PA was the only predictor of change in FMD. No relationships were evident between changes in body composition and FMD. CONCLUSIONS vascular function decreased between summer and autumn in this cohort. There were no relationships between change in FMD and changes in body composition or low/moderate-intensity PA. The associations between FMD and high-intensity PA suggests that future interventions should encourage this form of behavior, particularly at the times of year associated with lower PA.

A protocol to encourage accelerometer wear in children and young people

Abstract Background: Improving compliance to physical activity (PA) monitoring is critical for obtaining valid, comparable data free from inconsistencies that occur during data reduction. The first aim of this study was to investigate children (8–11 years) and young people’s (12–15 years) views on strategies to promote habitual wear of hip (ActiGraph) and wrist-worn (GENEActiv) accelerometers. The second aim was to subsequently develop a protocol to reduce participant and researcher burden and maximise accelerometer wear time data. Methods: An interpretivist methodology was used with semi-structured, mixed-gender focus groups in seven elementary (n = 10; 47 children) and five high schools (n = 10; 49 young people). Focus groups were transcribed verbatim and outcomes from deductive and inductive analysis were represented via pen profiles. Results: Deductive content analysis revealed four general dimensions: (1) participant driven compliance strategies; (2) reasons for non-compliance to wear time; (3) strategies to improve accelerometer care; (4) reasons for non-compliance to study conditions. Children perceived popular wear time compliance strategies to be: (1) sticky note reminders; (2) mobile phone reminders; (3) social conformity, whereas young people’s perceptions were: (1) social conformity; (2) mobile phone reminders; (3) monetary compensation. Conclusions: Where possible, compliance strategies should accommodate the varying preferences of children and young people (CYP). It is recommended that future accelerometry based research adopts a formative phase. In the absence of a formative research phase, future research should consider the use of this informed protocol to improve compliance to PA monitoring in CYP.

Assessment of biochemical liver markers, physical activity, fitness and body mass index for a cardiometabolic risk model in childhood

The aim of this study was to investigate clustered cardiometabolic risk scores in healthy 10‐ to 12‐year‐olds using anthropometric characteristics, measurements of cardiorespiratory fitness (CRF) and physical activity and blood markers of metabolic disease. We also evaluated how including markers of liver cell injury would affect the clustered cardiometabolic risk assessment model.

Individual calibration of accelerometers in children and their health-related implications

ABSTRACT This study compared children’s physical activity (PA) levels, the prevalence of children meeting current guidelines of ≥60 minutes of daily moderate to vigorous PA (MVPA), and PA-health associations using individually calibrated (IC) and empirical accelerometer cutpoints. Data from 75 (n = 32 boys) 10–12 year old children were included in this study. Clustered cardiometabolic (CM) risk, directly measured cardiorespiratory fitness (CRF), anthropometric and 7 day accelerometer data were included within analysis. PA data were classified using Froude anchored IC, Evenson et al. (Evenson, K. R., Catellier, D. J., Gill, K., Ondrak, K. S., & McMurray, R. G. (2008). Calibration of two objective measures of physical activity for children. Journal of Sports Sciences, 26(14), 1557–1565. doi:10.1080/02640410802334196) (Ev) and Mackintosh et al. (Mackintosh, K. A., Fairclough, S. J., Stratton, G., & Ridgers, N. D. (2012). A calibration protocol for population-specific accelerometer cutpoints in children. PLoS One, 7(5), e36919. doi:10.1371/journal.pone.0036919) (Mack) cutpoints. The proportion of the cohort meeting ≥60mins MVPA/day ranged from 37%-56% depending on the cutpoints used. Reported PA differed significantly across the cutpoint sets. IC LPA and MPA were predictors of CRF (LPA: standardised β = 0.32, p = 0.002, MPA: standardised β = 0.27 p = 0.013). IC MPA also predicted BMI Z-score (standardised β = −0.35, p = 0.004). Ev VPA was a predictor of BMI Z-score (standardised β = −0.33, p = 0.012). Cutpoint choice has a substantial impact on reported PA levels though no significant associations with CM risk were observed. Froude IC cutpoints represent a promising approach towards classifying children’s PA data.