Leib J. Golub

The diagnosis of ovarian cancer: Results of the study of 210 patients by the Philadelphia Committee for the Study of Pelvic Cancer☆

Abstract 1. 1. Two hundred ten cases of ovarian carcinoma taken from the records of the Philadelphia Committee for the Study of Pelvic Cancer have been reviewed. 2. 2. The greater incidence of ovarian carcinoma in women who were nulliparous or only para i seems significant. 3. 3. The symptoms complained of showed no characteristic pattern. The importance of determining the cause of genital bleeding is emphasized. 4. 4. The aid of the pathologist and the use of frozen sections are suggested.

The delay period in carcinoma of the vagina: With observations on age incidence and survival rate

Abstract From our data we have concluded that: 1. The incidence of carcinoma of the vagina is related to increasing age. 2. No racial predisposition was noted. 3. The most common presenting symptom was abnormal vaginal bleeding. 4. In approximately 25 per cent of cases there was no delay in diagnosis. The incidence of physician delay was about the same as patient delay. In approximately 30 per cent of cases, the total delay to diagnosis exceeded 8 months. 5. There was usually no delay from diagnosis to treatment. 6. Fourteen per cent of the patients have already survived more than 5 years. 7. No relationship could be observed between length of delay and outcome.

Teen-age dysmenorrhea; a statistical evaluation of the role of suggestion in treatment.

Abstract 1. A total of 2,706 girls of four secondary schools in two separate experiments were questioned about dysmenorrhea before and after a period of routine body-conditioning exercises. Students of the experimental schools were repeatedly told that the exercises would cure dysmenorrhea; students of the control schools were told nothing about any possible effect of the exercises on dysmenorrhea. 2. None of the schools showed any significant change in the incidence of dysmenorrhea from the beginning to the end of the experiment. 3. Of those free of dysmenorrhea at the beginning of the experiment, 12.4 to 20.6 per cent suffered from dysmenorrhea at the conclusion. 4. There was no significant difference in “cure” rate between control and experimental schools. Altogether, 23.1 per cent of those with dysmenorrhea were relieved of dysmenorrhea. This figure may be taken as an estimate of the proportion of teen-age cases which resolve spontaneously during an interval of six months to a year.

Therapeutic exercises for teen-age dysmenorrhea

Abstract 1. 1. During a period of more than 8 years, 5,324 girls of nineteen Philadelphia Junior High, Senior High, and Vocational Schools were treated for dysmenorrhea by either the Billig or Mosher exercises. 2. 2. Both exercises gave approximately the same results. On the average, more than three fourths of the girls were either “cured” (complete absence of symptoms for at least the last 3 months of follow-up) or improved. This rate varied from school to school and ranged from 60 to 100 per cent. 3. 3. The over-all average of “cure” per school was 20 per cent. This is practically the same per cent of cases that, in a previous study, resolved without any therapy. 4. 4. Although there is no specific evidence in our study that exercises affect the rate of total cures, they seem to offer a simple easy approach for at least partial relief of dysmenorrhea.

A new exercise for dysmenorrhea

Abstract 1. 1. A new therapeutic exercise for dysmenorrhea has been described. It consists of two components: (a) trunk twisting and bending, and (b) trunk extension with backward leg raising. This new exercise is much simpler to perform, requires little or no supervision, and could easily be incorporated into routine gymnastic activities. 2. 2. A comparison of results in dysmenorrheic high school girls treated by Billig or Mosher exercises and those treated by a new exercise shows the latter to be equallyas effective as the Billig or Mosher.

The crush syndrome in obstetrics and gynecology.

Abstract In a review of the maternal deaths in Philadelphia since the formation of the Maternal Mortality Committee of the County Medical Society seven maternal deaths were found which showed the “crush syndrome” with lower nephron nephrosis. An additional case of twisted ovarian cyst is included in the report. The obstetrical cases included placenta abruptio, ectopic, and birth trauma. Particular stress is placed on prevention of shock or its treatment by early and frequent blood transfusions.

The histopathologic diagnoses of the atypical endometrium

Abstract Attention has been called to the variability of the histologic findings in different portions of curettings removed for various clinical conditions, and hence the necessity of utilizing as frequently as possible the procedure of curettage rather than that of biopsy. Because of the present inadequate state of our knowledge and because of our inability to satisfactorily correlate many histopathologic findings with the hormonal status of the patient or with the inherent responsiveness of the endometrium, it is felt inadvisable in many instances to attempt all inclusive specific diagnoses. It is considered more advisable in these cases to restrict ones self to full descriptive reports supplemented by consultation and discussion between clinician and pathologist, in the hope that the future may bring clarification and unity to these objectively recorded findings.