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Leonard B. Crast

Bristol-Myers Squibb

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Publication

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Tetrahedron Letters | 1991

Synthesis of phenoxyacetyl-N-(hydroxydioxocyclobutenyl)cycloserines

Yasutsugu Ueda; Leonard B. Crast; Amarendra B. Mikkilineni; Richard Anthony Partyka

Abstract The synthesis and antibacterial activity of a potential antibiotic, phenoxyacetyl-(L)-cycloserine activated by a cyclobutenedione moiety, is described.

Archive | 1974

Production of p-hydroxycephalexin

Leonard B. Crast; William J. Gottstein

Journal of Medicinal Chemistry | 1981

Synthesis and beta-lactamase inhibitory properties of 2 beta-(chloromethyl)-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide.

William J. Gottstein; Leonard B. Crast; Robert G. Graham; Ute J. Haynes; Donald N. Mcgregor

Archive | 1985

3-propenyl cephalosporin solvates

Leonard B. Crast

The Journal of Antibiotics | 1989

SYNTHESIS AND IN VITRO ACTIVITY OF NEW SEMI-SYNTHETIC COUMERMYCIN ANALOGS: CHEMICAL MODIFICATION AT THE C-3 AMIDE

Yasutsugu Ueda; Julia M. Chuang; Leonard B. Crast; R. A. Partyka

Archive | 1967

S-SUBSTITUTED-THIOACETAMIDO-CEPHALOSPORINS

Leonard B. Crast

Journal of Organic Chemistry | 1988

A selective cleavage of the oxazole moiety in noviosylcoumarin antibiotics a new process to key intermediates for coumermycin analogue synthesis

Yasutsugu Ueda; Julia M. Chuang; Leonard B. Crast; Richard Anthony Partyka

Archive | 1969

PROCESS FOR THE PREPARATION OF 7-(ALPHA-(4 - PYRIDYLTHIO)ACETAMIDO)CEPHALOSPORANIC ACIDS

Leonard B. Crast; Robert Edward Havranek

Archive | 1977

Methoxymethyl esters of substituted imidazolidinyl-3-methyl-3-cephem-4-carboxylic acids

Leonard B. Crast; Robert G. Graham

The Journal of Antibiotics | 1974

3-ACYLTHIOMETHYL CEPHALOSPORINS

John M. Essery; Ute Corbin; Vilmars Sprancmanis; Leonard B. Crast; Robert G. Graham; Peter F. Misco; David Willner; Donald N. Mcgregor; Lee C. Cheney

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Lee C. Cheney

Bristol-Myers Squibb

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John C. Godfrey

Bristol-Myers Squibb

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John M. Essery

Bristol-Myers Squibb

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Robert G. Graham

Bristol-Myers Squibb

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Yasutsugu Ueda

Bristol-Myers Squibb

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Donald N. Mcgregor

Bristol-Myers Squibb

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Julia M. Chuang

Bristol-Myers Squibb

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Richard Anthony Partyka

Bristol-Myers Squibb

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Robert Edward Havranek

Bristol-Myers Squibb

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William J. Gottstein

Bristol-Myers Squibb

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