Leopoldo Borrego

Office-based radiation therapy for cutaneous carcinoma: Evaluation of 710 treatments

Skin cancers are the most common malignancies and, historically, ionizing radiation has played an important role in their treatment. However, less experienced dermatologists generally consider radiation last in the line of therapeutic options. The authors sought to evaluate the effectiveness and safety of office‐based elective radiation therapy for cutaneous carcinoma.

Dermatologists in hospital wards: an 8-year study of dermatology consultations.

Background: The value of dermatologists as consultants is increasing. Objective: To evaluate the activity of dermatologists as inpatient consultants. Methods: Retrospective study of consultations to Dermatology of inpatients, visits per consultation, referral service, procedures performed, delay until visit and diagnoses based on ICD-9. Results: 3,144 requests generated 4,824 visits, 200 biopsies, 107 cultures and other procedures. The mean delay between request and visit was 0.75 days. The requesting service was recorded in 3,097 cases: 21.5% by Internal Medicine, 11.4% by Pediatrics, 8.3% by Neurology and 6.2% by the Infectious Diseases Unit. Follow-up was recommended in 12.4% by the Dermatology Service and in 8% by a dermatologist. Reliable diagnoses were recorded for 2,832 consultations. The most frequent diagnostic groups were diseases of the skin and subcutaneous tissue (ICD-9: 680–709) in 58%, infectious and parasitic diseases (ICD-9: 001–139) in 20%, and neoplasm (ICD-9: 140–239) in 5.7%. The most frequent diagnoses were contact dermatitis (ICD-9: 692.X) in 8.9%, drug reactions (ICD-9: 693.0) in 7.4%, candidiasis (ICD-9:112.X) in 7.1% and seborrheic dermatitis (ICD-9: 690) in 5.3%. Conclusions: Most diagnoses were of a specific cutaneous disease and the dermatologist would be in the best position to evaluate those that inpatients acquire.

Naevus spilus as a precursor of cutaneous melanoma: report of a case and literature review

Naevus spilus is defined as a melanocytic macule in which there are dark maculopapular speckles. We describe a patient with a superficial spreading malignant melanoma arising in a congenital naevus spilus, and review the literature on this association.

Patch testing in children with hand eczema. A 5‐year multicentre study in Spain

Background. Hand eczema is common in children, but affected children are seldom patch tested. Relatively few studies have assessed patch testing in the paediatric population, and none has specifically evaluated its use in hand eczema in children.

Patch testing with formaldehyde and formaldehyde-releasers: multicentre study in Spain (2005–2009)

Background. Formaldehyde and formaldehyde‐releasers are common causes of allergic contact dermatitis.

Update of the Topical Treatment of Psoriasis

Topical therapy continues to be one of the pillars of psoriasis management. Topical corticosteroids and vitamin D analogs are the drugs of choice during the induction phase, and vitamin D analogs continue to be drugs of choice for maintenance therapy. Tazarotene and dithranol are suitable options in patients with certain, specific characteristics. The calcineurin inhibitors can be considered to be second-line treatment for psoriasis of the face and flexures. The efficacy and safety of the fixed-dose combination of betamethasone and calcipotriol in the induction phase is greater than that of either drug alone. The combination of corticosteroids with salicylic acid achieves better results than corticosteroids in monotherapy. None of the drugs evaluated stands out over the others in all clinical situations, and their use must therefore be individualized in each patient and adjusted according to the course of the disease.

Lupus eritematoso neonatal: 4 casos y revisión clínica

Resumen El lupus eritematoso neonatal (LEN) es una enfermedad poco frecuente del recien nacido debido al paso transplacentario de anticuerpos maternos anti-Ro/SSA, anti-La/SSB y/o anti-U 1 RNP en la que las afectaciones cutaneas y cardiacas son las mas destacadas. Realizamos un estudio retrospectivo de casos diagnosticados de LEN en los ultimos 10 anos en el Hospital Universitario Insular de Gran Canaria en el que se obtuvieron datos completes de 4 enfermos. En 3 casos se presentaron anticuerpos circulantes anti-Ro en la madre y en los neonatos, mientras que en el otro era anti-RNP. Dos madres estaban diagnosticadas de lupus sistemico, una de enfermedad mixta del tejido conjuntivo y otra de vasculitis leucocitoclastica. Las lesions cutaneas consistieron en lesiones urticariformes y descamativas. Un paciente presento ulceracion. El estudio histologico de las lesiones urticariformes mostro un infiltrado perivascular inespecifico; las lesiones descamativas fueron compatibles con lupus eritematoso subagudo.

Revisión actualizada del tratamiento tópico de la psoriasis

Topical therapy continues to be one of the pillars of psoriasis management. Topical corticosteroids and vitamin D analogs are the drugs of choice during the induction phase, and vitamin D analogs continue to be drugs of choice for maintenance therapy. Tazarotene and dithranol are suitable options in patients with certain, specific characteristics. The calcineurin inhibitors can be considered to be second-line treatment for psoriasis of the face and flexures. The efficacy and safety of the fixed-dose combination of betamethasone and calcipotriol in the induction phase is greater than that of either drug alone. The combination of corticosteroids with salicylic acid achieves better results than corticosteroids in monotherapy. None of the drugs evaluated stands out over the others in all clinical situations, and their use must therefore be individualized in each patient and adjusted according to the course of the disease.

Pediatric Dermatology Consultations: A Retrospective Analysis of Inpatient Consultations Referred to the Dermatology Service

Abstract:  To analyze the care provided by consultant dermatologists to hospitalized pediatric patients, we retrospectively studied the records of inpatient pediatric consultation requests received by a hospital dermatology department between 2000 and 2009. The diagnoses were recorded according to the International Classification of Diseases, Ninth Revision (ICD‐9). In a high percentage of cases, the problem was addressed in a single visit, and few additional tests were ordered. The most common diagnostic groups were diseases of the skin and subcutaneous tissue (ICD‐9: 680–709). The most frequent specific diagnosis was atopic dermatitis (ICD‐9: 691.8). Our series shows that the role of dermatologists as consultants for pediatric inpatients is similar to their role in outpatient consultations.

Correlation between lesion site and concentration of dimethyl fumarate in different parts of shoes in patients with contact dermatitis caused by dimethyl fumarate in footwear.

Background. Dimethyl fumarate (DMF) has been identified as being responsible for an outbreak of shoe contact dermatitis in Europe. All reported cases to date have involved the dorsa of the toes and the dorsa of the feet, sometimes in association with other areas.