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Loredana Valentino

Sigma-Tau

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Publication

Featured researches published by Loredana Valentino.

Bioorganic & Medicinal Chemistry | 1998

Synthesis and biological evaluation of 2-Hydroxy derivatives of digitoxigenin and 3-Epidigitoxigenin

Mauro Gobbini; Giuseppe Marazzi; Gloria Padoani; Luisa Quadri; Loredana Valentino; Maria Pia Zappavigna; Piero Melloni

The four stereoisomers of the 2-hydroxy derivatives of digitoxigenin and 3-epidigitoxigenin have been synthesized, their structures established by NMR, and their binding affinity for the digitalis receptor on Na+, K(+)-ATPase evaluated. These derivatives showed lower affinities than the parent compounds. The hydrophilic hydroxy groups in the alpha position are more detrimental to the affinity than hydroxy groups in the beta position.

Archive | 1995

17-(4-pyridazinyl) -5β, 14β-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same

Luisa Quadri; Luigi Bernardi; Giuseppe Bianchi; Patrizia Ferrari; Piero Melloni; Loredana Valentino

Archive | 1993

Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders

Luisa Quadri; Luigi Bernardi; Patrizia Ferrari; Mauro Gobbini; Piero Melloni; Loredana Valentino

Archive | 1993

17B-(3-Furyl) and 17B-(4-pyridazinyl)-5beta,14beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same

Luisa Quadri; Luigi Bernardi; Giuseppe Bianci; Patrizia Ferrari; Piero Melloni; Loredana Valentino

Archive | 1993

New cyclopentanperhydrophenanthren-17beta-(hydroxy or alkoxy)-17alpha-(aryl or heterocyclyl)-3beta-derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same

Mauro Gobbini; Mara Ferrandi; Marco Frigerio; Piero Melloni; Marco Torri; Loredana Valentino

Archive | 1995

Digitoxigenin and dihydrodigitoxigenin 3β-derivatives and pharmaceutical compositions comprising same for the treatment of cardiovascular disorders

Piero Melloni; Luigi Bernardi; Patrizia Ferrari; Mauro Gobbini; Marco Torri; Loredana Valentino

Archive | 1993

Cyclopentanperhydrophenanthren-17β-(hydroxy or alkoxy)-17α-(Aryl or heterocyclyl)-3β-derivatives active on the cardiovascular system, and pharmaceutical compositions containing same

Mauro Gobbini; Mara Ferrandi; Marco Frigerio; Piero Melloni; Marco Torri; Loredana Valentino

Archive | 1993

Cardioactive 17b-(3-furyl) and 17b-(4-pyridazinyl) -5beta, 14beta-androstane derivatives, processes for their preparation and pharmaceutical compositions thereof

Luisa Quadri; Luigi Bernardi; Giuseppe Bianci; Patrizia Ferrari; Piero Melloni; Loredana Valentino

Archive | 1993

3-beta-digitoxigenin derivatives and dihidrodigitoxigenina and pharmaceutical compositions containing them for the treatment of hypertension.

Piero Melloni; Luigi Bernardi; Patrizia Ferrari; Mauro Gobbini; Marco Torri; Loredana Valentino

Archive | 1993

Digitoxigenin und Dihydrodigitoxigenin 3-beta-Derivate und pharmazeutische Präparate davon, zur Behandlung von hypertonie Digitoxigenin and Dihydrodigitoxigenin 3-beta derivatives and pharmaceutical compositions thereof for the treatment of hypertension

Piero Melloni; Luigi Bernardi; Patrizia Ferrari; Mauro Gobbini; Marco Torri; Loredana Valentino

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Piero Melloni

Sigma-Tau

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Mauro Gobbini

Sigma-Tau

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Luigi Bernardi

Sigma-Tau

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Patrizia Ferrari

University of Milan

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Marco Torri

Sigma-Tau

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Luisa Quadri

Sigma-Tau

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Mara Ferrandi

Sigma-Tau

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Marco Frigerio

Sigma-Tau

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Giuseppe Bianchi

Vita-Salute San Raffaele University

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Giuseppe Bianci

Sigma-Tau

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