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Dive into the research topics where Lorraine Chuman is active.

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Featured researches published by Lorraine Chuman.


Cell | 1991

The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins

Mark Stamnes; Bih-Hwa Shieh; Lorraine Chuman; Greg L. Harris; Charles S. Zuker

Mutations in the Drosophila ninaA gene cause dramatic reductions in rhodopsin levels, leading to impaired visual function. The ninaA protein is a homolog of peptidyl-prolyl cis-trans isomerases. We find that ninaA is unique among this family of proteins in that it is an integral membrane protein, and it is expressed in a cell type-specific manner. We have used transgenic animals misexpressing different rhodopsins in the major class of photoreceptor cells to demonstrate that ninaA is required for normal function by two homologous rhodopsins, but not by a less conserved member of the Drosophila rhodopsin gene family. This demonstrates in vivo substrate specificity in a cyclophilin-like molecule. We also show that vertebrate retina contains a ninaA-related protein and that ninaA is a member of a gene family in Drosophila. These data offer insights into the in vivo role of this important family of proteins.


Journal of Cell Biology | 1979

Retention of differentiated properties in an established dog kidney epithelial cell line (MDCK).

Rindler Mj; Lorraine Chuman; Lisa G. Shaffer; Milton H. Saier


Proceedings of the National Academy of Sciences of the United States of America | 1979

Growth of Madin-Darby canine kidney epithelial cell (MDCK) line in hormone-supplemented, serum-free medium.

Mary Taub; Lorraine Chuman; Milton H. Saier; Gordon Sato


Cancer Research | 1976

Relationship of Cell Growth Behavior in Vitro to Tumorigenicity in Athymic Nude Mice

Charles D. Stiles; Walter Desmond; Lorraine Chuman; Gordon Sato; Milton H. Saier


Cancer Research | 1976

Growth Control of Heterologous Tissue Culture Cells in the Congenitally Athymic Nude Mouse

Charles D. Stiles; Walter Desmond; Lorraine Chuman; Gordon Sato; Milton H. Saier


FEBS Journal | 1989

Acyl carrier protein is present in the mitochondria of plants and eucaryotic micro‐organisms

Lorraine Chuman; Stuart Brody


Journal of Supramolecular Structure and Cellular Biochemistry | 1981

Alterations in growth requirements of kidney epithelial cells in defined medium associated with malignant transformation

Mary Taub; Ben Ü; Lorraine Chuman; Rindler Mj; Milton H. Saier; Gordon Sato


Journal of Cellular Physiology | 1983

Loss of the PGE1 requirement for MDCK cell growth associated with a defect in cyclic AMP phosphodiesterase

Mary Taub; Milton H. Saier; Lorraine Chuman; Sue Hiller


Journal of Cellular Physiology | 1985

Characterization of chemically and virally transformed variants of Madin-Darby canine kidney (MDCK) epithelial cells

Paula Boerner; Rindler Mj; Lorraine Chuman; Milton H. Saier


Archive | 1976

The congenitally athymic nude mouse.

Charles D. Stiles; Walter Desmond; Lorraine Chuman; G S Saier; O C In

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Gordon Sato

University of California

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Walter Desmond

University of California

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Mary Taub

University at Buffalo

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Rindler Mj

University of California

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Ben Ü

University of California

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Greg L. Harris

University of California

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