Lourdes Bolla de Lezcano

Perianal herpetic ulcers in immunosuppressed patients. Report of two cases

Genital herpes is the most common cause of ulcers in sexually transmitted diseases (STDs). It is presented as a single or multiple, painful injury, accompanied by bilateral, also painful, lymphadenopathy. In immunocompromised patients, such as those affected by HIV, Herpes Simplex Virus (HSV) infections have a variety of clinical manifestations; they may be located, scattered or atypical. In addition, lesions may be more extensive and persistent than HIV-negative patients. We present two cases of immunocompromised patients with perianal herpetic ulcers, one HIV carrier, and the other with leukopenia caused by visceral Leishmaniasis.

Cutaneous metastases from primary carcinomas of unknown origin. Contribution with3 cases and brief review

Metastases of unknown primary site occurs in about 5-10% of patients diagnosed with cancer. Usually appear after diagnosis of the primary cancer, but may be the first clinical sign of a tumor of unknown origin or the first sign of relapse of cancer. Cancer treatment is based on the recognition of the primary neoplasm, which raise diagnostic and therapeutic challenges. Skin biopsy should be considered in newly emerging lesions in cancer patients in addition to those lesions of sudden onset that are slow to heal, prone to bleeding or vascular appearance, that are not resolved with appropriate treatment. We present three cases of cutaneous metastases as the first manifestation, from which the primary tumor was found.

comment:Sporotrichoid atopic prurigo. A common condition with an unusual clinical presentation

Prurigo is a very common dermatosis with no racial nor sex preference. It is frequently encountered in patients with atopic phenomenon. The causes of prurigo are mainly hypersensitivity reaction, inflammation and infection. Prurigo can also be classified simply as acute or chronic prurigo. The latter is more common type and one of its variant is actinic prurigo. Actinic prurigo is quite common in temperate regions. There are chronic recurrent prurigo nodules on sun-exposed areas of the body such as nape and sides of the neck, backs of the hands, extensor forearms and upper chest, and is usually resistant to treatment. Sporotrichoid atopic prurigo is a rare variant where itchy prurigo nodules are seen along the lymphatic or vascular drainage area, and usually seen in lower limbs. Sporotrichoid atopic prurigo is commonly seen in atopic patients who do hard works and are prone to minor trauma. This includes military persons, people who work in paddy fields and manual labor. The case presented by Beatriz Di Martino Ortiz et al is an unusual type of sporotrichoid atopic prurigo affecting the left axilla. Its cause seems to be inflammation caused by infection. So it is rapidly resolved by systemic antibiotics.