Oilda Knopfelmacher

Paracoccidioidomicosis en paciente HIV

Resumen La Paracoccidioidomicosis es la micosis profunda sistemica mas frecuente en America Latina, causada por el hongo dimorfico Paracoccidioides brasiliensis. La forma clinica mas frecuente es la cronica multifocal con afectacion pulmonar y muco-cutanea. Con la diseminacion del VIH el diagnostico de paracoccidioidomicosis debe tenerse en cuenta particularmente en areas endemicas. Las manifestaciones cutaneas en esta ultima son muy frecuentes; mas del 90% de pacientes las presentan en alguna fase de la evolucion. Se presenta el caso de un varon adulto joven HIV + con paracoccidioidomicosis cronica multifocal.

Ictiosis hystrix (nevus epidérmico diseminado) asociado a hiperqueratosis epidermolítica

Resumen La Ictiosis Hystrix es una anomalia del desarrollo epidermico frecuentemente desfigurante, que consiste en una erupcion diseminada y bilateral, que afecta el tronco y las extremidades. Si bien esta entidad no es infrecuente, la presencia de hiperqueratosis epidermolitica en la biopsia cutanea es un hallazgo relativamente poco comun, como lo demuestra la literatura. Presentamos el caso de un nino con nevus epidermico diseminado asociado al hallazgo histologico de hiperqueratosis epidermolitica. El tratamiento es desalentador.

Cutaneous metastases from primary carcinomas of unknown origin. Contribution with3 cases and brief review

Metastases of unknown primary site occurs in about 5-10% of patients diagnosed with cancer. Usually appear after diagnosis of the primary cancer, but may be the first clinical sign of a tumor of unknown origin or the first sign of relapse of cancer. Cancer treatment is based on the recognition of the primary neoplasm, which raise diagnostic and therapeutic challenges. Skin biopsy should be considered in newly emerging lesions in cancer patients in addition to those lesions of sudden onset that are slow to heal, prone to bleeding or vascular appearance, that are not resolved with appropriate treatment. We present three cases of cutaneous metastases as the first manifestation, from which the primary tumor was found.

comment:Sporotrichoid atopic prurigo. A common condition with an unusual clinical presentation

Prurigo is a very common dermatosis with no racial nor sex preference. It is frequently encountered in patients with atopic phenomenon. The causes of prurigo are mainly hypersensitivity reaction, inflammation and infection. Prurigo can also be classified simply as acute or chronic prurigo. The latter is more common type and one of its variant is actinic prurigo. Actinic prurigo is quite common in temperate regions. There are chronic recurrent prurigo nodules on sun-exposed areas of the body such as nape and sides of the neck, backs of the hands, extensor forearms and upper chest, and is usually resistant to treatment. Sporotrichoid atopic prurigo is a rare variant where itchy prurigo nodules are seen along the lymphatic or vascular drainage area, and usually seen in lower limbs. Sporotrichoid atopic prurigo is commonly seen in atopic patients who do hard works and are prone to minor trauma. This includes military persons, people who work in paddy fields and manual labor. The case presented by Beatriz Di Martino Ortiz et al is an unusual type of sporotrichoid atopic prurigo affecting the left axilla. Its cause seems to be inflammation caused by infection. So it is rapidly resolved by systemic antibiotics.

[Bloch-Sulzberger's syndrome (Incontinentia pigmenti). Contribution with a case report].

Incontinentia pigmenti (IP) is a rare genodermatosis. Skin lesions, that are present in all patients affected, evolve in stages. The first is the erythematous blistering stage, wich differential diagnosis includes a wide variety of diseases. We present a case of a female neonate with blisters present at birth, where the skin biopsy confirmed the diagnosis of IP.