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Dive into the research topics where Luke Austin is active.

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Featured researches published by Luke Austin.


Orthopedics | 2012

Hemiarthroplasty Versus Reverse Total Shoulder Arthroplasty for Acute Proximal Humerus Fractures in Elderly Patients

Grant E. Garrigues; Peter S. Johnston; Matthew D. Pepe; Bradford Tucker; Matthew L. Ramsey; Luke Austin

Proximal humerus fractures are the third most common fracture in elderly patients. Hemiarthroplasty has been the treatment of choice in patients with bone quality and fracture patterns not amenable to open reduction and internal fixation. Reverse total shoulder arthroplasty is a newer option that appears to be less dependent on tuberosity healing than hemiarthroplasty. The authors hypothesized that reverse total shoulder arthroplasty provides improved functional outcomes compared with hemiarthroplasty for fractures in elderly patients.A retrospective review was performed of all patients treated with arthroplasty for acute proximal humerus fractures in an orthopedic practice using a Current Procedural Terminology code search, patient charts, and radiographs. Validated outcome scores were used to assess satisfaction, function, and general well-being. Twenty-three patients were treated for acute proximal humerus fractures (11 reverse total shoulder arthroplasties and 12 hemiarthroplasties). Three patients were lost to follow-up, and 6 patients were deceased. Mean follow-up was 3.6 years (range, 1.3-8 years). Reverse total shoulder arthroplasty outperformed hemiarthroplasty with regard to forward flexion, American Shoulder and Elbow Society score, University of Pennsylvania shoulder score, and Single Assessment Numerical Evaluation score.Reverse total shoulder arthroplasty is a reliable option for acute, proximal humerus fractures that are not amenable to closed treatment or reconstruction in elderly patients. Improved functional outcomes when compared with hemiarthroplasty must be balanced against the increased cost and limited life expectancy of patients with this injury.


Spine | 2006

Reliability of a novel classification system for thoracolumbar injuries: the Thoracolumbar Injury Severity Score.

Alexander R. Vaccaro; Eli M. Baron; James A. Sanfilippo; Sidney M. Jacoby; Jacob Steuve; Eric Grossman; Matthew J. DiPaola; Paul Ranier; Luke Austin; Ray Ropiak; Michael Ciminello; Chuka Okafor; Matthew D. Eichenbaum; Venkat Rapuri; Eric B. Smith; Fabio Orozco; Peter Ugolini; Mark Fletcher; Jonathan Minnich; Gregory Goldberg; Jared T. Wilsey; Joon Y. Lee; Moe R. Lim; Anthony S. Burns; Ralph J. Marino; Christian P. DiPaola; Laura Zeiller; Steven C. Zeiler; James S. Harrop; D. Greg Anderson

Study Design. Prospective study of 5 spine surgeons rating 71 clinical cases of thoracolumbar spinal injuries using the Thoracolumbar Injury Severity Score (TLISS) and then re-rating the cases in a different order 1 month later. Objective. To determine the reliability of the TLISS system. Summary of Background Data. The TLISS is a recently introduced classification system for thoracolumbar spinal column injures designed to simplify injury classification and facilitate treatment decision making. Before being widely adopted, the reliability of the TLISS must be studied. Methods. A total of 71 cases of thoracolumbar spinal trauma were distributed on CD-ROM to 5 attending spine surgeons, including clinical/radiographic data, details of the TLISS, and a scoring sheet in which cases would be scored using the system. The surgeons were later assigned the task with the cases reordered. Intraobserver and interobserver reliability was calculated for TLISS components, total score, and surgeons treatment decision using the Cohen unweighted kappa coefficients and Spearman rank-order correlation. Results. Interrater reliability assessed by generalized kappa coefficients was 0.33 ± 0.03 for injury mechanism, 0.91 ± 0.02 for neurologic status, 0.35 ± 0.03 for posterior ligamentous complex status, 0.29 ± 0.02 for TLISS total, and 0.52 ± 0.03 for treatment recommendation. Respective results using the Spearman correlation were 0.35 ± 0.04, 0.94 ± 0.01, 0.48 ± 0.04, 0.65 ± 0.03, and 0.51 ± 0.04. Surgeons agreed with the TLISS recommendation 96.4% of the time. Intrarater kappa coefficients were 0.57 ± 0.04 for injury mechanism, 0.93 ± 0.02 for neurologic status, 0.48 ± 0.04 for posterior ligamentous complex status, 0.46 ± 0.03 for TLISS total, and 0.62 ± 0.04 for treatment recommendation. Respective results using the Spearman correlation were 0.70 ± 0.04, 0.95 ± 0.02, 0.59 ± 0.05, 0.77 ± 0.04, and 0.59 ± 0.05. Conclusions. The TLISS has good reliability and compares favorably to other contemporary thoracolumbar fracture classification systems.


Arthroscopy | 2012

The Prevalence of Articular Cartilage Changes in the Knee Joint in Patients Undergoing Arthroscopy for Meniscal Pathology

Michael C. Ciccotti; Matthew J. Kraeutler; Luke Austin; Ashwin Rangavajjula; Benjamin Zmistowski; Steven B. Cohen; Michael G. Ciccotti

PURPOSE The purposes of this study were to evaluate the prevalence of articular cartilage changes in the knee joint and to analyze predictive factors for these changes in patients undergoing arthroscopy for meniscal pathology. METHODS Between March 2005 and June 2009, 1,010 patients underwent arthroscopic meniscectomy or meniscal repair by the senior author. During surgery, a precise diagram was used to carefully note the presence, location, size, and Outerbridge grade of changes to the articular surfaces of the knee joint. The prevalence of articular cartilage changes was calculated for 6 age groups: younger than 20 years, 20 to 29 years, 30 to 39 years, 40 to 49 years, 50 to 59 years, and 60 years or older. Demographic data including gender, ethnicity, smoking status, and body mass index (BMI) were acquired from patient charts. RESULTS Overall, 48% of patients showed changes to the medial compartment, 25% to the lateral compartment, and 45% to the patellofemoral compartment. Eighty-five percent of patients aged 50 to 59 years and 86% of patients aged 60 years or older showed articular cartilage changes to at least 1 knee compartment. In contrast, only 13% of patients aged younger than 20 years and 32% of patients aged 20 to 29 years showed changes to at least 1 compartment. A significant relation was found between age and the development of articular cartilage changes in each of the 3 compartments (P < .0001). BMI was also significantly related to articular cartilage changes in the medial and patellofemoral compartments (P < .0001) but not the lateral compartment (P = .08). CONCLUSIONS This study shows a high prevalence of articular cartilage damage as defined by the Outerbridge classification in patients undergoing arthroscopic surgery for meniscal pathology. Risk factors that correlate with articular cartilage damage include increasing age, elevated BMI, medial compartment pathology, and knee contractures. LEVEL OF EVIDENCE Level IV, therapeutic case series.


Journal of Medical Imaging and Radiation Oncology | 2011

Safety and efficacy of radiation therapy as secondary prophylaxis for heterotopic ossification of non-hip joints.

Mark V. Mishra; Luke Austin; Javad Parvizi; Matthew L. Ramsey; Timothy N. Showalter

Introduction: Prophylactic radiation therapy (RT) is an established adjuvant therapy for heterotopic ossification (HO) of the hip when delivered in the immediate pre‐ or postoperative setting. Its role in prevention of recurrence after excision of HO is supported by randomised trials for HO of the hip, but there is scant evidence to demonstrate the safety and efficacy of a similar approach in non‐hip joints. In the current study, we evaluate radiological and functional outcomes after prophylactic RT for prevention of HO of the knee and upper extremity.


Orthopaedic Surgery | 2015

Thromboelastography Predictive of Death in Trauma Patients

Ian Kane; Fabio Orozco; Zachary D. Post; Luke Austin; Kris E. Radcliff

To determine if thromboelastography (TEG) is predictive of patient outcomes following traumatic injury.


Journal of Bone and Joint Surgery, American Volume | 2010

Fatal Venous Air Embolism During Shoulder Arthroscopy

Benjamin Zmistowski; Luke Austin; Michael G. Ciccotti; Eric T. Ricchetti; Gerald R. Williams

Venous air embolism is a potential surgical complication when a negative pressure gradient exists between the surgical site and the right atrium of the heart. It occurs more commonly when the operative site is over the heart, the pressure of gas in the body cavity exceeds that of the venous sinusoids (15 to 30 mm Hg), air rather than carbon dioxide is injected, or the venous sinusoids of bone marrow are exposed1,2. Shoulder arthroscopy satisfies many of these criteria: the beach-chair and lateral decubitus positions place the surgical site over the right atrium, the standard settings for arthroscopic pumps are at pressures of >30 mm Hg, air bubbles are often observed entering the joint, and venous sinusoids are exposed anytime that osseous work (i.e., distal clavicular excision, acromioplasty, or fracture repair) is performed. Two case reports of fatal venous air embolism following knee arthroscopy3,4 with intentional air insufflation have appeared in the literature, but we are not aware of any reported case following liquid-only arthroscopy. We present the case of a patient undergoing revision arthroscopic rotator cuff repair and distal clavicular excision who experienced acute intraoperative cardiopulmonary collapse and was resuscitated, but died on postoperative day 14. The patient was undergoing liquid-only arthroscopy, and we postulated that air entered the joint through an unrecognized air reservoir: commercially available 3-L arthroscopic fluid bags. A forty-seven-year-old woman presented with a six-month history of severe pain in the right shoulder. The history, physical examination, and magnetic resonance imaging revealed a small, full-thickness tear of the supraspinatus tendon. After the failure of six months of conservative treatment, she elected to undergo arthroscopic supraspinatus repair and subacromial …


Journal of Shoulder and Elbow Surgery | 2012

Additional x-ray views increase decision to treat clavicular fractures surgically

Luke Austin; Michael J. O’Brien; Benjamin Zmistowski; Eric T. Ricchetti; Matthew J. Kraeutler; Ashish Joshi; John M. Fenlin

BACKGROUND The trauma series for clavicular fractures includes anterior-posterior and 20° cephalic tilt radiographs. Management of clavicular fractures either nonoperatively or operatively is dependent on radiographs. We hypothesized that the interobserver and intraobserver reliability of the treatment decision would be improved with a novel 4-view radiographic series over the standard 2-view radiographic trauma series. METHODS Four-view radiographic analysis was performed and consisted of anterior-posterior, 20° cephalic tilt, 45° cephalic tilt, and 45° caudal tilt. Radiographs were collected for 50 consecutive patients presenting with acute midshaft clavicular fractures. Four blinded orthopedists were asked to judge whether each case should be treated either operatively or nonoperatively based on the standard 2-view series and then the 4-view series a minimum of 1 week later. This procedure was repeated a minimum of 2 months later. The incidence of surgeon treatment modification was analyzed along with interobserver and intraobserver reliability of both series. RESULTS In 17 cases, at least 1 surgeon changed the treatment decision between 2- and 4-view review. In 13 cases (26%), the treatment was changed from nonoperative to operative. Significantly greater intraobserver reliability was observed for the 4- versus 2-view series (R = 0.76 and R = 0.64, respectively), with no difference in interobserver reliability (intraclass correlation coefficient of 0.88 and 0.87, respectively). CONCLUSIONS With the use of a novel 4-view radiographic series that includes orthogonal viewing angles, surgeons are more likely to treat clavicular fractures operatively and their intraobserver reliability is improved, suggesting improved visualization of anterior-posterior displacement.


Journal of Arthroplasty | 2008

Hypoxemia After Total Joint Arthroplasty : A Problem on the Rise

Luke Austin; Luis Pulido; Raymond Ropiak; Manny Porat; Javad Parvizi; Richard H. Rothman

Total joint arthroplasty (TJA) is categorized as a major risk factor for thromboembolic complications. The importance of hypoxemia during the postoperative period is subject of controversy. This prospective study elucidates the incidence and etiology of hypoxemia after TJA. Furthermore, we intended to assess the predictive value of clinical findings in identifying the etiology of hypoxemia after TJA. Of 1971 patients, 78 (4.0%) experienced an acute episode of hypoxemia during their hospitalization after TJA. Hypoxemia as the initial presenting sign, predicted major complications, defined as life-threatening if left untreated, in 32% of the hypoxic population. These diagnoses included pulmonary embolism, pulmonary edema, and pneumonia. Tachypnea was the only independent factor associated with pulmonary embolism. Our study presents the incidence and etiology of hypoxemia after TJA, and we recommend a heightened appreciation for the hypoxemic patient.


American Journal of Sports Medicine | 2015

Sleep Disturbance Associated With Rotator Cuff Tear Correction With Arthroscopic Rotator Cuff Repair

Luke Austin; Matthew D. Pepe; Bradford Tucker; Robert Nugent; Brandon Eck; Fotios P. Tjoumakaris

Background: Sleep disturbance is a common complaint of patients with a rotator cuff tear. Inadequate and restless sleep, along with pain, is often a driving symptom for patients to proceed with rotator cuff repair. To date, no studies have examined sleep disturbance in patients undergoing rotator cuff repair, and there is no evidence that surgery improves sleep disturbance. Hypothesis: Sleep disturbance is prevalent in patients with a symptomatic rotator cuff tear, and sleep disturbance improves after arthroscopic rotator cuff repair. Study Design: Case series; Level of evidence, 4. Methods: A total of 56 patients undergoing arthroscopic rotator cuff repair for full-thickness tears were enrolled in a prospective study. Patients were surveyed preoperatively and postoperatively at intervals of 2, 6, 12, 18, and 24 weeks. Patient outcomes were scored using the Pittsburgh Sleep Quality Index (PSQI), Simple Shoulder Test (SST), visual analog scale for pain (VAS), and single assessment numeric evaluation (SANE). Demographic and surgical factors were also collected for analysis. Results: Preoperative PSQI scores indicative of sleep disturbance were reported in 89% of patients. After surgery, a statistically significant improvement in PSQI was achieved at 3 months (P = .0012; 91% follow-up) and continued through 6 months (P = .0179; 93% follow-up). Six months after surgery, only 38% of patients continued to have sleep disturbance. Multivariable linear regression of all surgical and demographic factors versus PSQI was performed and demonstrated that preoperative and prolonged postoperative narcotic use negatively affected sleep. Conclusion: Sleep disturbance is common in patients undergoing rotator cuff repair. After surgery, sleep disturbance improves to levels comparable with those of the general public. Preoperative and prolonged postoperative use of narcotic pain medication negatively affects sleep.


Journal of Bone and Joint Surgery, American Volume | 2010

Commercial Liquid Bags as a Potential Source of Venous Air Embolism in Shoulder Arthroscopy

Luke Austin; Benjamin Zmistowski; Bradford Tucker; Robin Hetrick; Patrick Curry; Gerald R. Williams

BACKGROUND Venous air embolism is a rare but potentially fatal complication of arthroscopy. Fatal venous air embolism has been reported with as little as 100 mL of air entering the venous system. During liquid-only arthroscopy, avenues for air introduction into the joint are limited. Therefore, we hypothesized that commercially prepared 3-L saline-solution bags are a source of potentially fatal amounts of gas that can be introduced into the joint by arthroscopic pumps. METHODS Eight 3-L arthroscopic saline-solution bags were obtained and visually inspected for air. The air was aspirated from four bags, and the volume of the air was recorded. A closed-system pump was prepared, and two 3-L bags were connected to it. The pump emptied into an inverted graduated cylinder immersed in a water bath. Both bags were allowed to run dry. Two more bags were then connected and also allowed to run dry. The air was quantified by the downward displacement of water. The experiment was then repeated with the four bags after the air had been aspirated from them. This experiment was performed at three institutions, with utilization of three pump systems and two brands of 3-L saline-solution bags. RESULTS Air was visualized in all bags, and the bags contained between 34 and 85 mL of air. Arthroscopic pumps can pump air efficiently through the tubing. The total volumes of gas ejected from the tubing after the four 3-L bags had been emptied were 75, 80, and 235 mL. When bags from which the air had been evacuated were used, no air exited the system. CONCLUSIONS Because a saline-solution arthroscopic pump is theoretically a closed system, venous air embolism has not been a concern. However, this study shows that it is possible to pump a fatal amount of air from 3-L saline-solution bags into an environment susceptible to the creation of emboli. Evacuation of air from the 3-L bags prior to use may eliminate this risk.

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Matthew D. Pepe

Thomas Jefferson University

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Bradford Tucker

Thomas Jefferson University

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Charles Wowkanech

Thomas Jefferson University

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Brandon Eck

Philadelphia College of Osteopathic Medicine

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Gerald R. Williams

Thomas Jefferson University

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Mark D. Lazarus

Thomas Jefferson University Hospital

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Alexander W. Aleem

Washington University in St. Louis

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