Luke B. Connelly

A cost-effectiveness analysis of adding a human papillomavirus vaccine to the Australian National Cervical Cancer Screening Program

BACKGROUND The cost-effectiveness of adding a human papillomavirus (HPV) vaccine to the Australian National Cervical Screening Program compared to screening alone was examined. METHODS A Markov model of the natural history of HPV infection that incorporates screening and vaccination was developed. A vaccine that prevents 100% of HPV 16/18-associated disease, with a lifetime duration of efficacy and 80% coverage offered through a school program to girls aged 12 years, in conjunction with current screening was compared with screening alone using cost (in Australian dollars) per life-year (LY) saved and quality-adjusted life-year (QALY) saved. Sensitivity analyses included determining the cost-effectiveness of offering a catch-up vaccination program to 14-26-year-olds and accounting for the benefits of herd immunity. RESULTS Vaccination with screening compared with screening alone was associated with an incremental cost-effectiveness ratio (ICER) of

Child health and the income gradient: Evidence from Australia

51 103 per LY and

Does injury compensation lead to worse health after whiplash? A systematic review

18 735 per QALY, assuming a cost per vaccine dose of

A History of the Term 'Moral Hazard'

115. Results were sensitive to assumptions about the duration of vaccine efficacy, including the need for a booster (

Optimising corticosteroid injection for lateral epicondylalgia with the addition of physiotherapy: A protocol for a randomised control trial with placebo comparison

68 158 per LY and

Complexities in understanding the role of compensation-related factors on recovery from whiplash-associated disorders: discussion paper 2

24 988 per QALY) to produce lifetime immunity. Accounting for herd immunity resulted in a more attractive ICER (

Research on injury compensation and health outcomes: ignoring the problem of reverse causality led to a biased conclusion

36 343 per LY and

Equity of health care financing in Iran: the effect of extending health insurance to the uninsured.

13 316 per QALY) for girls only. The cost per LY of vaccinating boys and girls was

A randomised clinical trial of a comprehensive exercise program for chronic whiplash: trial protocol

92 052 and the cost per QALY was

Economic Evaluation of Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile Infection in Australia.

33 644. The cost per LY of implementing a catch-up vaccination program ranged from