Lydia Rodríguez-Hahn

Clerodane diterpenoids of Salvia lineata

Abstract The aerial parts of Salvia lineata afforded, in addition to sitosterol, oleanolic acid and flavonoids of known structures, three clerodane derivatives related to salviarin and gensnerofolin B. The structures were elucidated by spectroscopic and chemical means.

Effect of Clerodane‐Type Diterpenoids Isolated from Salvia spp. on the Feeding Behaviour of Spodoptera littoralis

Twenty-nine clerodane-type diterpenoids isolated from species of Salvia growing in Mexico, or analogues of them, were tested for antifeedant activity against Spodoptera littoralis larvae using behavioural and electrophysiological bioassays. Eight of the compounds showed potent antifeedant activity in choice and no-choice bioassays and these compounds also stimulated dose-dependent responses from neurones in the lateral styloconic sensilla of S. littoralis.

Clerodane and aromatic seco-clerodane diterpenoids from salvia rhyacophua.

Abstract The known clerodane diterpenes salviarin 1 and 6β-hydroxy-7,8-dehydrobacchatricunactin 2, were isolated from Salvia rhyacophila together with five new clerodane diterpenoids 3-6 and 12. The structures of diterpenes 3-6 were established on spectral evidence and chemical transformations. Rhyacophiline is an aromatic seco-clerodane diterpenoid whose structure 12 was established by spectral means and X-ray diffraction analysis.

Neo-clerodane-type diterpenoids from Salvia keerlii

Abstract From the aerial parts of Salvia keerlii two new neo-clerodane diterpenoids have been isolated. Their structures: 8,12( R )epoxyneo-cleroda-3,13(14)-diene-18,19:15,16-diolide, kerlin and 7-acetoxy-12( R )hydroxyneoclerodane-3,13(14)-diene-18,19:15,16-diolide, kerlinolide, have been established by spectroscopic means. X-ray diffraction analysis was performed for kerlin.

Further ent-clerodane diterpenoids from Salvia melissodora

Abstract From the aerial parts of Salvia melissodora , ten ent -clerodane diterpenoids were isolated. One of the compounds had been isolated previously from another population of the same plant. However, seven of the compounds constitute new natural products. The structures of these compounds were established by spectroscopic and chemicals means. Oleanolic acid and sitosterol were also found in this species.

Structure of salvigenolide, a novel diterpenoid with a rearranged neo-clerodane skeleton from salviafulgens

Abstract From the aerial parts of Salvia fulgens Cav. (Labiatae) a new diterpenoid with a rearranged neo-clerodane skeleton was isolated. This novel compound named salvigenolide, showed a six-seven A/B ring system with a trans fussion. A probable biogenetic route is proposed. Its structure and relative stereochemistry as in 1 , were established by spectroscopic means and X-ray diffraction analysis.

Salvigenane and isosalvipuberulan diterpenoids from Salvia leucantha.

Abstract From the aerial parts of S. leucantha the rearranged neo-clerodane diterpenoid salvileucantholide was isolated. Its structure 1 was established by spectral means, chemical transformation and X-ray diffraction analysis. The salvigenane diterpenoid 4 and salvifaricin were also isolated from this source.

Clerodane Diterpenes in Labiatae

The chemical constituents of the Labiatae family have been studied mainly for their economic value which is closely related to their high content of essential oils. These consist mostly of volatile mono- and sesquiterpenes. There is much less information on the diterpenoid content of these plants although the latter has been considered (1) potentially more useful for taxonomic purposes.

Limonoids from Trichilia havanensis

Abstract The limonoids of the seeds of Trichilia havanensis were studied in two ripening stages. From the unripened seeds azadirone, havanensin triacetate and three new limonoids were isolated. The mature seeds contained havanesin triacetate and its hydroxy lactone derivative. The structures of the new limonoids were deduced by spectroscopic and chemical means.

Abietane diterpenoids from Salvia pubescens

Abstract From the aerial parts of Salvia pubescens , two new abietane diterpenoids were isolated and their structures established by spectroscopic means. The known 7α-acetoxy-royleanone, conacytone, nemorone and desacetylnemorone were also isolated.