Lyndall Molthan

The Heart in Progressive Muscular Dystrophy

A case of progressive muscular dystrophy with cardiac involvement in a young Negro man is reported. The presenting problem was cardiomegaly and congestive heart failure. It was not until compensation was achieved that the underlying myopathy became apparent. Death was unexpected and presumably sudden. An unusual finding at the postmortem examination was the marked thickening of the endocardium. The literature in regard to the clinical and pathologic manifestations of cardiac involvement in this myopathy is reviewed.

Enlargement of the Dombrock Blood Group System: the Finding of Anti‐Dob

Abstract. The finding of anti‐Doa, the antibody antithetical to anti‐Dob in the Dombrock blood group system, is here reported; its existence promotes Dombrock to fifth place amongst red cell antigen systems in order of potential usefulness in discriminating between white people.

Lu9, another new antigen of the Lutheran blood-group system.

Abstract. A new Lutheran antigen, Lu9, with a frequency of about 2%, has been recognized. It has an apparent allelic relationship to the high‐frequency character Lu6.

A New Antigen, Yka (York), and its Relationship to Csa (Cost)

Abstract. The antigen Yka is detected in 92 and 98% of the American Caucasian and Negro populations, respectively. In population studies with anti‐Yka and anti‐Csa, association was demonstrated between the two antigens; however, in two of three informative families Yka and Csa segregated independently. The possibility that these antigens have a relationship with leucocyte antigens is discussed.

A new antigen, McCa (McCoy), and its relationship to Kna(Knops).

The antigen McCa is detected in 98.5 and 96.7 per cent of the American Caucasian and Negro populations respectively. In population studies with anti‐McCa and anti‐Kna, a strong association was demonstrated between the two antigens, with 53 per cent of McC(a–) samples being Kn(a–) compared with a reported frequency for Kn(a–) of only 0.19 per cent.

Rh-D hemolytic disease in Negro and white infants: A comparison

Hemolytic disease of the newborn due to Rh-D has had lower morbidity and mortality rates in Negro than in white infants delivered at Temple University Hospital from 1946 to 1962. Negro and white mothers have shown a similar incidence of Rh sensitization and equal ability to produce anti-D antibody. Sixty per cent of affected Negro infants and 26.5 per cent of affected white infants did not require treatment. Neonatal mortality was 2 per cent for Negro, 8.5 per cent for white infants. Fewer Negro mothers have had stillbirths due to hemolytic disease. ABO hemolytic disease has shown equal severity in Negro and white infants.