M. Pushparaj

Hysteroscopic findings in women with primary and secondary infertility due to genital tuberculosis

To evaluate hysteroscopic findings of infertile women with genital tuberculosis.

Hysterosalpingographic findings in infertile women with genital tuberculosis

To evaluate the hysterosalpingographic findings from infertile women who were subsequently diagnosed with genital tuberculosis.

Angiokeratoma of vulva with coexisting human papilloma virus infection: a case report

We report a 25-year-old unmarried girl who developed multiple papular lesions on both labia majora with the past history of documented HPV-6 viral infection in the vulva. A wide local excision was performed and histopathological report confirmed a case of angiokeratoma. To the best of our knowledge this is the first case of angiokeratoma of vulva following chronic HPV infection.

Increased Difficulties and Complications Encountered During Hysteroscopy in Women with Genital Tuberculosis

BACKGROUND Genital tuberculosis (TB) in women is a common disease in developing countries, and hysteroscopy and laparoscopy are vital tools in diagnosis. STUDY OBJECTIVE To retrospectively compare the difficulties encountered and complications of hysteroscopy in women with and without genital TB. DESIGN Case-control clinical audit (Canadian Task Force classification II-1). SETTING Medical college and hospital. PATIENTS Ninety-nine women who underwent hysteroscopy, with or without other procedures, who were found to have genital TB at various investigations (group 1) and 289 women who underwent hysteroscopy during the same period with similar characteristics but without evidence of genital TB (group 2, controls). INTERVENTION Hysteroscopy. MEASUREMENTS AND MAIN RESULTS Difficulties encountered and complications observed were recorded, compared, and analyzed using the χ(2) and Fisher exact tests. Indications for hysteroscopy in the study vs the control group were infertility in 92 patients (92.92%) vs 124 (42.90 %), amenorrhea in 6 (6.66%) vs 12 (4.15%), and postmenopausal bleeding in 1 (1.11%) vs 29 (10.03%). Difficulties and complications were significantly higher in group 1. Inability to distend the cavity was observed in 8 women in group 1 (8.08%) vs 2 in group 2 (0.69%). Excessive bleeding was observed in 5 women in group 1 (5.05%) vs 1 in group 2 (0.35 %). Uterine perforation was observed in 8 women in group 1 (8.08%) vs 5 in group 2 (1.73%), and flare-up of genital TB was observed in 1 woman in group 1. CONCLUSION Hysteroscopy in women with genital TB is associated with difficulty in performing the procedure and with higher rates of complications.

O850 Abdomino-peritoneal tuberculosis masquerading as ovarian cancer: A retrospective study of 26 cases

The association between in vitro fluconazole and nystatin susceptibility with clinical outcome is poorly understood. The purpose of the study was to correlate fluconazole and nystatin susceptibility with clinical outcome for vulvovaginal candidosis (VVC). Two hundred and eighty-three patients with complicated VVC, which included 27 patients with VVC that had been caused by non-albicans species, were investigated at Peking University Shenzhen Hospital between April 2005 and December 2006. In vitro fluconazole and nystatin susceptibility was tested using E test or commercial agar diffusion test. The patients were treated with fluconazole or nystatin. The resistance rate of candida species for fluconazole and nystatin were 0.8% (1/132) and 0 (0/155). The mycological cure rate at day 7–14 and day 30–35 in fluconazole susceptible-dose dependent isolates was lower than that in fluconazole susceptible isolates (42.9% vs 88.7% and 28.6% vs 76.6%, p < 0.05). The mycological cure rate at day 7–14 and day 30–35 in VVC caused by Candida albicans (C. albicans) group and non-albicans species group was 85.6% (219/256) vs 88.9% (24/27) and 79.3% (203/256) vs 81.5% (22/27), p > 0.05. We conclude that fluconazole resistance was rare and both C. albicans and nonalbicans species were susceptible to nystatin. The decrease of fluconazole susceptibility was related with fluconazole therapeutic failure.